Hélène Blanché

TL;DR: It is shown that interbreeding, albeit of low magnitude, occurred among many hominin groups in the Late Pleistocene and a definitive list of substitutions that became fixed in modern humans after their separation from the ancestors of Neanderthals and Denisovans is established.

TL;DR: The results show that the processes underlyingccRCC tumorigenesis may vary in different populations and suggest that AA may be an important ccRCC carcinogen in Romania, a finding with major public health implications.

TL;DR: An original NF1 investigation strategy is presented and a comprehensive mutation analysis of 565 unrelated patients from the NF‐France Network is reported, pointing out the need to perform an exhaustive NF1 screening in the case of molecular discordant‐related patients.

TL;DR: This paper conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry.

TL;DR: The results strongly suggest that the longevity-related differences in the poly(ADP-ribosyl)ation capacity of human lymphoblastoid cell lines cannot be explained by genetic polymorphisms in the PARP-1 coding sequence and that other mechanisms have to be considered as potential regulators of specific poly( ADP- ribosyl]ation capacity.