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Sadia Shakoor
Researcher at Aga Khan University
Publications - 120
Citations - 3247
Sadia Shakoor is an academic researcher from Aga Khan University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 19, co-authored 97 publications receiving 2326 citations. Previous affiliations of Sadia Shakoor include The Aga Khan University Hospital & Aga Khan University Hospital.
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Journal ArticleDOI
Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED).
James A Platts-Mills,Sudhir Babji,Ladaporn Bodhidatta,Jean Gratz,Jean Gratz,Rashidul Haque,Alexandre Havt,Benjamin J.J. McCormick,Monica McGrath,Maribel Paredes Olortegui,Amidou Samie,Sadia Shakoor,Dinesh Mondal,Ila Fn Lima,Dinesh Hariraju,Bishnu Bahadur Rayamajhi,Shahida Qureshi,Furqan Kabir,Pablo Peñataro Yori,Brenda Mufamadi,Caroline Amour,J. Daniel Carreon,Stephanie A. Richard,Dennis Lang,Pascal O. Bessong,Esto Mduma,Tahmeed Ahmed,Aldo A. M. Lima,Carl J. Mason,Anita K. M. Zaidi,Zulfiqar A Bhutta,Margaret Kosek,Richard L. Guerrant,Michael Gottlieb,Mark A. Miller,Gagandeep Kang,Eric R. Houpt +36 more
TL;DR: The findings suggest that although single-pathogen strategies have an important role in the reduction of the burden of severe diarrhoea disease, the effect of such interventions on total diarrhoeal incidence at the community level might be limited.
Journal ArticleDOI
Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins.
Elizabeth J. Klemm,Sadia Shakoor,Andrew J. Page,Farah Naz Qamar,Kim Judge,Dania K. Saeed,Vanessa K. Wong,Timothy J. Dallman,Satheesh Nair,Stephen Baker,Stephen Baker,Ghazala Shaheen,Shahida Qureshi,Mohammad Tahir Yousafzai,Muhammad Khalid Saleem,Zahra Hasan,Gordon Dougan,Gordon Dougan,Rumina Hasan +18 more
TL;DR: The first large-scale emergence and spread of a novel extensively drug-resistant S. Typhi clone in Sindh, Pakistan is reported, highlighting the evolving threat of antibiotic resistance in S. typhi and the value of antibiotic susceptibility testing and whole-genome sequencing in understanding emerging infectious diseases.
Journal ArticleDOI
The MAL-ED Study: A Multinational and Multidisciplinary Approach to Understand the Relationship Between Enteric Pathogens, Malnutrition, Gut Physiology, Physical Growth, Cognitive Development, and Immune Responses in Infants and Children Up to 2 Years of Age in Resource-Poor Environments
Angel Mendez Acosta,Cesar Banda Chavez,Julian Torres Flores,Maribel Paredes Olotegui,Silvia Rengifo Pinedo,Dixner Rengifo Trigoso,Angel Orbe Vasquez,Imran Ahmed,Didar Alam,Asad Ali,Zulfiqar A Bhutta,Shahida Qureshi,Sadia Shakoor,Sajid Bashir Soofi,Ali Turab,Aisha K. Yousafzai,Anita K. M. Zaidi,Ladaporn Bodhidatta,Carl J. Mason,Sudhir Babji,Anuradha Bose,Sushil John,Gagandeep Kang,Beena Kurien,Jayaprakash Muliyil,Mohan Venkata Raghava,Anup Ramachandran,Anuradha Rose,William Pan,Ramya Ambikapathi,Danny Carreon,Vivek Charu,Leyfou Dabo,Viyada Doan,Jhanelle Graham,Christel Hoest,Stacey Knobler,Dennis Lang,Benjamin J.J. McCormick,Monica McGrath,Mark A. Miller,Archana Mohale,Gaurvika M. L. Nayyar,Stephanie Psaki,Zeba A Rasmussen,Stephanie A. Richard,Jessica C. Seidman,Vivian Ota Wang,Rebecca Blank,Michael Gottlieb,Karen H. Tountas,Caroline Amour,Estomih Mduma,Tahmeed Ahmed,AM Shamsir Ahmed,Mondol Dinesh,Fahmida Tofail,Rashidul Haque,Iqbal Hossain,M Munirul Islam,Mustafa Mahfuz,Ram Krishna Chandyo,Prakash Shrestha,Rita Shrestha,Manjeswori Ulak,Robert E. Black,Laura E. Caulfield,William Checkley,Ping Chen,Margaret Kosek,Gwenyth O. Lee,Pablo Peñataro Yori,Laura E. Murray-Kolb,Barbara A. Schaefer,Laura L. Pendergast,Cláudia B. Abreu,Alexandre Havt Bindá,H. Costa,Alessandra Di Moura,José Q. Filho,Álvaro M. Leite,Aldo A. M. Lima,Noélia L. Lima,Ila F. N. Lima,Bruna Leal Lima Maciel,Milena Lima de Moraes,Francisco Suetônio Bastos Mota,Reinaldo B. Oriá,Josiane da Silva Quetz,Alberto M. Soares,Erling Svensen,Strand Tor,Crystal L. Patil,Pascal O. Bessong,Cloupas Mahopo,Angelina Mapula,Cebisa Nesamvuni,Emanuel Nyathi,Amidou Samie,Leah J. Barrett,Jean Gratz,Richard Guerrant,Eric R. Houpt,Liz Olmsted,William A. Petri,James A Platts-Mills,Rebecca J. Scharf,Binob Shrestha,Sanjaya K. Shrestha +108 more
TL;DR: The hypothesis is that enteropathogen infection contributes to undernutrition by causing intestinal inflammation and/or by altering intestinal barrier and absorptive function, and it is further postulated that this leads to growth faltering and deficits in cognitive development.
Journal ArticleDOI
Epidemiology and Impact of Campylobacter Infection in Children in 8 Low-Resource Settings: Results From the MAL-ED Study.
Caroline Amour,Jean Gratz,Estomih Mduma,Erling Svensen,Elizabeth T. Rogawski,Monica McGrath,Jessica C. Seidman,Benjamin J.J. McCormick,Sanjaya K. Shrestha,Amidou Samie,Mustafa Mahfuz,Shahida Qureshi,Aneeta Hotwani,Sudhir Babji,Dixner Rengifo Trigoso,Aldo A. M. Lima,Ladaporn Bodhidatta,Pascal O. Bessong,Tahmeed Ahmed,Sadia Shakoor,Gagandeep Kang,Margaret Kosek,Richard L. Guerrant,Dennis Lang,Michael Gottlieb,Eric R. Houpt,James A Platts-Mills +26 more
TL;DR: A association between Campylobacter and linear growth shortfalls and both increased intestinal permeability and intestinal and systemic inflammation is demonstrated and potential interventions are identified.
Journal ArticleDOI
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Stephanie W. Lo,Rebecca A. Gladstone,Andries J. van Tonder,John A. Lees,Mignon du Plessis,Rachel Benisty,Noga Givon-Lavi,Paulina A. Hawkins,Jennifer E. Cornick,Brenda Kwambana-Adams,Brenda Kwambana-Adams,Pierra Y. Law,Pak-Leung Ho,Martin Antonio,Dean Everett,Ron Dagan,Anne von Gottberg,Keith P. Klugman,Lesley McGee,Robert F. Breiman,Stephen D. Bentley,Abdullah Brooks,Alejandra Corso,Alexander Davydov,Alison J. Maguire,Andrew J. Pollard,Anmol M. Kiran,Anna Skoczynska,Benild Moiane,Bernard Beall,Betuel Sigaúque,David M. Aanensen,Deborah Lehmann,Diego Faccone,Ebenezer Foster-Nyarko,Ebrima Bojang,Ekaterina Egorova,Elena Voropaeva,Eric Sampane-Donkor,Ewa Sadowy,Godfrey Bigogo,Helio Mucavele,Houria Belabbès,Idrissa Diawara,Jennifer C. Moïsi,Jennifer R. Verani,Jeremy D. Keenan,Jyothish N Nair Thulasee Bhai,Kedibone M. Ndlangisa,Khalid Zerouali,K L Ravikumar,Leonid Titov,Linda de Gouveia,Maaike Alaerts,Margaret Ip,Maria Cristina de Cunto Brandileone,Hasanuzzaman,Metka Paragi,Michele Nurse-Lucas,Mushal Ali,Naima Elmdaghri,Nicholas J. Croucher,Nicole Wolter,Nurit Porat,Ozgen Koseoglu Eser,Patrick Eberechi Akpaka,Paul Turner,Paula Gagetti,Peggy-Estelle Tientcheu,Philip E. Carter,Rafal Mostowy,Rama Kandasamy,Rebecca Ford,Rebecca Henderson,Roly Malaker,Sadia Shakoor,Samanta Cristine Grassi Almeida,Samir K. Saha,Sanjay Doiphode,Shabir A. Madhi,Shamala Devi Sekaran,Somporn Srifuengfung,Stephen K. Obaro,Stuart C. Clarke,Susan A. Nzenze,Tamara Kastrin,Theresa J. Ochoa,Veeraraghavan Balaji,Waleria Hryniewicz,Yulia Urban +89 more
TL;DR: In this paper, a whole-genome sequenced 3233 invasive pneumococcal disease isolates from laboratory-based surveillance programs in Hong Kong (n=78), Israel, South Africa, Malawi, Nigeria, The Gambia, and USA were collected from children younger than 3 years.