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Vanessa Kiyomi Ota

Researcher at Federal University of São Paulo

Publications -  87
Citations -  2043

Vanessa Kiyomi Ota is an academic researcher from Federal University of São Paulo. The author has contributed to research in topics: Schizophrenia & Psychosis. The author has an hindex of 18, co-authored 74 publications receiving 1186 citations. Previous affiliations of Vanessa Kiyomi Ota include McGill University & Douglas Mental Health University Institute.

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Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Vassily Trubetskoy, +432 more
- 08 Apr 2022 - 
TL;DR: In this article , a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals was conducted, and the authors reported common variant associations at 287 distinct genomic loci.
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Early life adversity, genomic plasticity, and psychopathology

TL;DR: Assessment of emerging data for the role of epigenetic mechanisms in stress-related psychiatric disorders with a focus on future research is assessed.
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Effects of risperidone on cytokine profile in drug-naïve first-episode psychosis.

TL;DR: The results show a specific cytokine profile in FEP patients (monocytic and regulatory T-cell activation) and suggest immunoregulatory effects of risperidone treatment, characterized by suppressant effects on monocytic, Th2, and T-regulatory functions.
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High predictive value of immune-inflammatory biomarkers for schizophrenia diagnosis and association with treatment resistance.

TL;DR: The findings of this study reinforce that SCZ is associated with a pro-inflammatory profile and suggest that some immune mediators may be used as reliable biomarkers for the diagnosis of SCZ and treatment resistance.
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Activation of the immune-inflammatory response system and the compensatory immune-regulatory system in antipsychotic naive first episode psychosis.

TL;DR: The findings indicate that (a) FEP patients are prone to the detrimental effects of M1, Th-1,Th-17 and Th-2 cells, which may contribute to long-lasting abnormalities in brain circuitry; and (b) in FEP, the CIRS might contribute to recovery from the acute phase of illness.