Y
Yutaka Suzuki
Researcher at University of Tokyo
Publications - 875
Citations - 42146
Yutaka Suzuki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 85, co-authored 767 publications receiving 35471 citations. Previous affiliations of Yutaka Suzuki include Japan Agency for Medical Research and Development & Institute for the Physics and Mathematics of the Universe.
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Journal ArticleDOI
Comparative Analysis of Patient-Matched PDOs Revealed a Reduction in OLFM4-Associated Clusters in Metastatic Lesions in Colorectal Cancer.
Takuya Okamoto,David duVerle,Katsuyuki Yaginuma,Yasuko Natsume,Hitomi Yamanaka,Daisuke Kusama,Mayuko Fukuda,Mayuko Yamamoto,Fanny Perraudeau,Upasna Srivastava,Yukie Kashima,Ayako Suzuki,Yuuta Kuze,Yu Takahashi,Masashi Ueno,Yoshiharu Sakai,Tetsuo Noda,Koji Tsuda,Yutaka Suzuki,Satoshi Nagayama,Ryoji Yao +20 more
TL;DR: In this article, the authors investigated the cellular heterogeneity of metastatic colorectal cancer (CRC) and established 72 patient-derived organoids (PDOs) from 21 patients.
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Indoleamine 2,3-dioxygenase 1 is highly expressed in glioma stem cells
Yoshinari Ozawa,Shun Yamamuro,Emiko Sano,Juri Tatsuoka,Yuya Hanashima,Sodai Yoshimura,Koichiro Sumi,Hiroyuki Hara,Tomohiro Nakayama,Yutaka Suzuki,Atsuo Yoshino +10 more
TL;DR: GSCs exhibit treatment resistance with immunosuppression via high expression levels of IDO1, and could represent a novel target for GBM treatment, according to the immune systems of GSCs.
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A Novel Spiro-Heterocyclic Compound Identified by the Silkworm Infection Model Inhibits Transcription in Staphylococcus aureus.
Atmika Paudel,Hiroshi Hamamoto,Suresh Panthee,Keiichi Kaneko,Shigeki Matsunaga,Motomu Kanai,Yutaka Suzuki,Kazuhisa Sekimizu +7 more
TL;DR: It is revealed that GPI0363 could bind to SigA, inhibit promoter-specific transcription in vitro, and prolong the survival of mice infected with methicillin-resistant S. aureus infections.
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From the laboratory to the field: assaying histone methylation at FLOWERING LOCUS C in naturally growing Arabidopsis halleri.
Haruki Nishio,Diana Mihaela Buzas,Atsushi J. Nagano,Atsushi J. Nagano,Atsushi J. Nagano,Yutaka Suzuki,Sumio Sugano,Motomi Ito,Shin-Ichi Morinaga,Hiroshi Kudoh +9 more
TL;DR: The Field ChIP method described here will facilitate comprehensive chromatin analysis of AhgFLC in the future to contribute to the authors' understanding of gene regulation in fluctuating natural environments.
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Single-cell and spatial analyses of cancer cells: toward elucidating the molecular mechanisms of clonal evolution and drug resistance acquisition
TL;DR: In this paper, a new method, collectively called spatial transcriptome (ST) analysis, has been developed and rapidly applied to various clinical specimens, particularly focusing on the latest anti-epidermal growth factor receptor tyrosine kinase inhibitor, osimertinib.