Yutaka Suzuki

TL;DR: It is demonstrated that the tumorigenic subpopulation of mouse LGR5+ cells exists in a slow-cycling state and a unique 22-gene signature that characterizes these slow-Cycling CSC is identified, suggesting that inhibition of slow-cycle CSC by targeting the TCF1–PROX1–CDKN1C pathway is an effective strategy to combat refractory colon cancer in combination with conventional chemotherapy.

TL;DR: A trans-omic network of insulin action in FAO hepatoma cells is constructed using transcriptomic data, western blotting analysis of signaling proteins, and metabolomic data to gain molecular insight into how liver cells interpret physiological insulin signals to regulate cellular functions.

TL;DR: Two polyclonal antibodies against synthetic oligopeptides comprising amino acid sequences in the human lysosomal protective protein recognized the precursor and the N-terminal sequence of the 32-kDa mature protein subunit, and in normal fibroblasts.

TL;DR: Using the oligo-capping method, a full-length-enriched cDNA library from erythrocytic stage parasites is produced and led to detection of three new gene candidates that were not previously known.

TL;DR: This update of H-DBAS correlated RNA-Seq tag information to the AS exons and splice junctions, and presented a new comparative genomics viewer so that users can empirically understand the evolutionary turnover of AS.