Y
Yutaka Suzuki
Researcher at University of Tokyo
Publications - 875
Citations - 42146
Yutaka Suzuki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 85, co-authored 767 publications receiving 35471 citations. Previous affiliations of Yutaka Suzuki include Japan Agency for Medical Research and Development & Institute for the Physics and Mathematics of the Universe.
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Journal ArticleDOI
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1–associated myelopathy/tropical spastic paraparesis
Misako Nagasaka,Makoto Yamagishi,Naoko Yagishita,Natsumi Araya,Seiichiro Kobayashi,Junya Makiyama,Miyuki Kubokawa,Junji Yamauchi,Daisuke Hasegawa,Ariella Coler-Reilly,Shuntaro Tsutsumi,Yu Uemura,Ayako Arai,Ayako Takata,Eisuke Inoue,Yasuhiro Hasegawa,Toshiki Watanabe,Yutaka Suzuki,Kaoru Uchimaru,Tomoo Sato,Yoshihisa Yamano +20 more
TL;DR: The increased mortality in patients with HAM/TSP and a significant effect of ATLL on their prognosis are demonstrated and genomic changes occurring in HAM/ TSP patients at the actual time of their ATLL transformation are described.
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Long-read sequencing for non-small-cell lung cancer genomes.
Yoshitaka Sakamoto,Liu Xu,Masahide Seki,Toshiyuki T. Yokoyama,Masahiro Kasahara,Yukie Kashima,Akihiro Ohashi,Yoko Shimada,Noriko Motoi,Katsuya Tsuchihara,Susumu Kobayashi,Takashi Kohno,Yuichi Shiraishi,Ayako Suzuki,Yutaka Suzuki +14 more
TL;DR: The application of a long-read sequencer, PromethION, for analyzing human cancer genomes is reported, finding that it is possible to genotype known cancerous mutations, such as point mutations, and that long- read sequencing is particularly useful for precisely identifying and characterizing structural aberrations.
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Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells
Tomohiro Miyai,Junichiro Takano,Takaho A. Endo,Eiryo Kawakami,Yasutoshi Agata,Yasutaka Motomura,Masato Kubo,Yukie Kashima,Yutaka Suzuki,Hiroshi Kawamoto,Tomokatsu Ikawa +10 more
TL;DR: RNA-seq analysis of lymphoid progenitors in bone marrow strongly supported the three-step TF network model during specification of multipotent progenitor toward B-cell lineage in vivo, and will provide a blueprint for studying the normal and neoplastic development of B lymphocytes.
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The First Nationwide Survey and Genetic Analyses of Bardet-Biedl Syndrome in Japan
Makito Hirano,Wataru Satake,Kenji Ihara,Ikuya Tsuge,Shuji Kondo,Ken Saida,Hiroyuki Betsui,Kazuhiro Okubo,Hikaru Sakamoto,Shuichi Ueno,Yasushi Ikuno,Ryu Ishihara,Hiromi Iwahashi,Mitsuru Ohishi,Toshiyuki Mano,Toshihide Yamashita,Yutaka Suzuki,Yusaku Nakamura,Susumu Kusunoki,Tatsushi Toda +19 more
TL;DR: The first nationwide survey of BBS in Japan is conducted by sending questionnaires to 2,166 clinical departments with board-certified specialists and found 7 patients with clinically definite BBS, and this is the first study to identify genetic alterations in Japanese patients with BBS.
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The histone modification H3 lysine 27 tri-methylation has conserved gene regulatory roles in the triplicated genome of Brassica rapa L
Ayasha Akter,Satoshi Takahashi,Weiwei Deng,Daniel J. Shea,Etsuko Itabashi,Motoki Shimizu,Naomi Miyaji,Kenji Osabe,Namiko Nishida,Yutaka Suzuki,Chris A. Helliwell,Motoaki Seki,William James Peacock,William James Peacock,Elizabeth S. Dennis,Elizabeth S. Dennis,Ryo Fujimoto +16 more
TL;DR: Investigation of the distribution of the histone mark tri-methylation of H3K27 (H3K 27me3) in B. rapa and its role in the control of gene expression at two stages of development and among paralogs in the triplicated genome found it to have a similar distribution in two inbred lines.