Y
Yutaka Suzuki
Researcher at University of Tokyo
Publications - 875
Citations - 42146
Yutaka Suzuki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 85, co-authored 767 publications receiving 35471 citations. Previous affiliations of Yutaka Suzuki include Japan Agency for Medical Research and Development & Institute for the Physics and Mathematics of the Universe.
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Journal ArticleDOI
Single-cell RNA sequencing unravels heterogeneity of skeletal progenitors and cell–cell interactions underlying the bone repair process
Mikako Nakayama,Hiroyuki Okada,Masahide Seki,Yutaka Suzuki,Ung-il Chung,Shinsuke Ohba,Hironori Hojo +6 more
TL;DR: In this paper , the authors performed a combinatorial analysis consisting of lineage tracing for skeletal progenitors using the Sox9-CreERT2;R26RtdTomato mouse line followed by single-cell RNA sequencing (scRNA-seq) analysis using a mouse model of calvarial bone repair.
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Characterization of Aldosterone-producing Cell Cluster (APCC) at Single-cell Resolution
Norifusa Iwahashi,Hironobu Umakoshi,Tsugio Seki,Celso E. Gomez-Sanchez,Kuniaki Mukai,Makoto Suematsu,Yuta Umezawa,Mototsugu Oya,Takeo Kosaka,Masahide Seki,Yutaka Suzuki,Yutaka Horiuchi,Yoshihiro Ogawa,Koshiro Nishimoto +13 more
TL;DR: The scRNA-seq results revealed the gene expression characteristics of APCC at single-cell resolution and show that some ZG cells remodel to APCC, and inferred the developmental trajectory.
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Characterization and purification of human β-galactosidase overexpressed in recombinant baculovirus-infectedSpodoptera frugiperda cells
TL;DR: Recently, an abundant expression of a full-length fl-galactosidase cDNA was achieved using a recombinant baculovirus expression vector and a catalytically active 84-kD precursor with post-translationally modified oligosaccharides was purified and further characterized.
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Transcriptome analysis reveals a role for the endothelial ANP-GC-A signaling in interfering with pre-metastatic niche formation by solid cancers
Takashi Nojiri,Miki Arai,Yutaka Suzuki,Motofumi Kumazoe,Takeshi Tokudome,Koichi Miura,Jun Hino,Hiroshi Hosoda,Mikiya Miyazato,Meinoshin Okumura,Shinpei Kawaoka,Kenji Kangawa +11 more
TL;DR: It is shown that the atrial natriuretic peptide (ANP), an endogenous hormone produced by the heart, inhibits pre-metastatic niche formation and metastasis of murine solid cancer models when pharmacologically supplied in vivo.
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Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity and Molecular Features of Ductal Carcinoma In Situ.
Momoko Tokura,Jun-ichi Nakayama,Marta Prieto-Vila,Sho Shiino,Masayuki Yoshida,Tomofumi Yamamoto,Naoaki Watanabe,Shinichi Takayama,Yutaka Suzuki,Koji Okamoto,Takahiro Ochiya,Takashi Kohno,Yasushi Yatabe,Akihiko Suto,Yusuke Yamamoto +14 more
TL;DR: Single-cell transcriptomic profiling of DCIS and invasive ductal carcinoma (IDC) provided novel insight into the intratumoral heterogeneity and molecular features ofDCIS, which exhibit properties similar to IDC.