Y
Yutaka Suzuki
Researcher at University of Tokyo
Publications - 875
Citations - 42146
Yutaka Suzuki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 85, co-authored 767 publications receiving 35471 citations. Previous affiliations of Yutaka Suzuki include Japan Agency for Medical Research and Development & Institute for the Physics and Mathematics of the Universe.
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Journal ArticleDOI
Essential Role of the Crk Family-Dosage in DiGeorge-like Anomaly and Metabolic Homeostasis
Akira Imamoto,Sewon Ki,Leiming Li,Kazunari Iwamoto,Venkat Maruthamuthu,John Devany,Ocean Lu,Tomomi Kanazawa,Suxiang Zhang,Takuji Yamada,Akiyoshi Hirayama,Shinji Fukuda,Yutaka Suzuki,Mariko Okada +13 more
TL;DR: It is shown that a 50% reduction of the family-combined dosage generates developmental defects, including aspects of DiGeorge/del22q11 syndrome in mice, and Crk/Crkl-shared pathways orchestrate metabolic homeostasis and cell behavior through widespread epigenetic controls.
Posted ContentDOI
Identification of physical interactions between genomic regions by enChIP-Seq
TL;DR: The data suggest that enChIP-Seq is a potentially useful tool for detecting physical interactions between genomic regions in a non-biased manner, which would facilitate elucidation of the molecular mechanisms underlying regulation of genome functions.
Posted ContentDOI
In utero gene transfer system for embryos before neural tube closure reveals a role for Hmga2 in the onset of neurogenesis
Naohiro Kuwayama,Yusuke Kishi,Yurie Maeda,Yurie Nishiumi,Yutaka Suzuki,Haruhiko Koseki,Yusuke Hirabayashi,Yukiko Gotoh +7 more
TL;DR: A novel method for manipulating genes in the early stage of mouse ectodermal and endodermal organogenesis is established and a key molecule that gives rise to neurogenic progenitors in the developing mouse neocortex is uncovered.
Posted ContentDOI
A functional RNA structure in the influenza A virus ribonucleoprotein complex for segment bundling
Naoki Takizawa,Koichi Higashi,Risa Kawaguchi,Yasuhiro Gotoh,Yutaka Suzuki,Tetsuya Hayashi,Ken Kurokawa +6 more
TL;DR: The global intersegment interactions and the secondary structure of the vRNA in virion were revealed and it was demonstrated that a pseudoknot structure was formed on a segment in the virion and the impairment of replication and packaging of the other specific segment was observed in cells infected with recombinant virus which had mutations in the pseudok not structure.
Journal ArticleDOI
β-Galactosidase-neuraminidase deficiency. Deficiency of a freeze-labile neuraminidase in leukocytes and fibroblasts
TL;DR: 4-Methylumbelliferyl neuraminidase activity was studied in fibroblasts, leukocytes, and frozen tissues from adult patients with β-galactosidase-neuraminidases deficiency and specific clinical manifestations.