Yutaka Suzuki

TL;DR: Liquid chromatography–tandem mass spectrometry and mRNA sequencing at seven developmental stages shows that the most substantial changes in the proteome take place towards later stages, between the morula and blastocyst, consistent with the cytoplasmic lattice-to-free ribosome transition being a key mediator of developmental regulation.

TL;DR: It is demonstrated that a coupling of localized spins with the zero-point motion of hydrogen atoms, that is, proton fluctuations in a hydrogen-bonded organic Mott insulator provides a different class of quantum spin liquids (QSLs), resulting in a quantum paraelectric (QPE) state.

TL;DR: It is shown that transient expression of centaurin-α1 in COS-7 cells results in specific activation of ERK, and the activation is inhibited by co-expression of a dominant negative form of Ras, which suggests that centaur in- α1 contributes to ERK activation in growth factor signaling, linking the PI3K pathway to the ERK mitogen-activated protein kinase pathway through its ability to interact with PIP3.

TL;DR: This work analyzed the transcriptome, transcription start sites (TSSs) and the chromatin landscape of the BmN4 cell line, which harbors the germ-line piRNA pathway to envision that the euchromatic, opened nature of unique piRNA clusters or piRNA cluster-associated TSSs allows pi RNA clusters to capture new insertions efficiently.

TL;DR: A large-scale collection of full-length cDNAs for several apicomplexa parasites is generated and indicates that the current gene models are likely to still be incomplete and have much room for improvement.