Y
Yutaka Suzuki
Researcher at University of Tokyo
Publications - 875
Citations - 42146
Yutaka Suzuki is an academic researcher from University of Tokyo. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 85, co-authored 767 publications receiving 35471 citations. Previous affiliations of Yutaka Suzuki include Japan Agency for Medical Research and Development & Institute for the Physics and Mathematics of the Universe.
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Journal ArticleDOI
TRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
Lamia’a Bahnassawy,Lamia’a Bahnassawy,Thanneer M. Perumal,Thanneer M. Perumal,Laura Gonzalez-Cano,Anna-Lena Hillje,Leila Taher,Wojciech Makalowski,Yutaka Suzuki,Georg Fuellen,Antonio del Sol,Jens Christian Schwamborn,Jens Christian Schwamborn +12 more
TL;DR: The data presented here reveal that TRIM32 directly regulates at least two of the four Yamanaka Factors, cMyc and Oct4, to modulate cell fate transitions, to regulate somatic cell reprogramming.
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Profiling ascidian promoters as the primordial type of vertebrate promoter
Kohji Okamura,Kohji Okamura,Riu Yamashita,Noriko Takimoto,Koki Nishitsuji,Koki Nishitsuji,Yutaka Suzuki,Takehiro Kusakabe,Kenta Nakai +8 more
TL;DR: It is inferred that CpG islands are not sufficiently ancient to be found in invertebrates, and probably appeared early in vertebrate evolution via some active mechanism and have since been maintained as part of vertebrate promoters.
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Novel Nucleoside Diphosphatase Contributes to Staphylococcus aureus Virulence.
Kenta Imae,Yuki Saito,Hayato Kizaki,Hiroki Ryuno,Han Mao,Atsushi Miyashita,Yutaka Suzuki,Kazuhisa Sekimizu,Chikara Kaito +8 more
TL;DR: RNA sequence analysis revealed that SA1684 is required for the expression of the virulence regulatory genes agr, sarZ, and sarX, as well as metabolic genes involved in glycolysis and fermentation pathways, which suggest that the novel nucleoside diphosphatase SA 1684 links metabolic pathways and virulence gene expression and plays an important role in S. aureus virulence.
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Cost-effective sequencing of full-length cDNA clones powered by a de novo-reference hybrid assembly.
Reginaldo Massanobu Kuroshu,Junichi Watanabe,Sumio Sugano,Shinichi Morishita,Yutaka Suzuki,Masahiro Kasahara +5 more
TL;DR: A program that assembles millions of short (36-nucleotide) reads collected from a single flow cell lane of Illumina Genome Analyzer to shotgun-sequence ∼800 human full-length cDNA clones, demonstrating a significant advantage over previous approaches.
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Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation.
Alexis Vandenbon,Alexis Vandenbon,Yutaro Kumagai,Yutaro Kumagai,Mengjie Lin,Yutaka Suzuki,Kenta Nakai +6 more
TL;DR: The timing of short-term changes of some histone modifications coincides with changes in transcriptional activity, but this is not the case for others, and dynamics in modifications more likely reflect strict regulation by stimulus-induced TFs and their interactions with chromatin modifiers.