Georgetown University

About: Georgetown University is a education organization based out in Washington D.C., District of Columbia, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 23377 authors who have published 43718 publications receiving 1748598 citations. The organization is also known as: GU & Georgetown.

EDA: Easy Data Augmentation Techniques for Boosting Performance on Text Classification Tasks

Abstract: We present EDA: easy data augmentation techniques for boosting performance on text classification tasks. EDA consists of four simple but powerful operations: synonym replacement, random insertion, random swap, and random deletion. On five text classification tasks, we show that EDA improves performance for both convolutional and recurrent neural networks. EDA demonstrates particularly strong results for smaller datasets; on average, across five datasets, training with EDA while using only 50% of the available training set achieved the same accuracy as normal training with all available data. We also performed extensive ablation studies and suggest parameters for practical use.

An African primate lentivirus (SIVsm) closely related to HIV-2

Abstract: THE ancestors of the human immunodeficiency viruses (HIV-1 and HIV-2) may have evolved from a reservoir of African non-human primate lentiviruses, termed simian immunodeficiency viruses (SIV)1. None of the SIV strains characterized so far are closely related to HIV-12–6. HIV-2, however, is closely related to SIV (SIVmac) isolated from captive rhesus macaques (Macaca mulatta)7. SIV infection of feral Asian macaques has not been demonstrated by serological surveys8,9. Thus, macaques may have acquired SIV in captivity by cross-species transmission from an SIV-infected African primate. Sooty mangabeys (Cercocebm atys), an African primate species indigenous to West Africa, however, are infected with SIV (SIVsm) both in captivity9–11and in the wild (P. Fultz, personal communication). We have molecularly cloned and sequenced SIVsm and report here that it is closely related to SIVmac and HIV-2. These results suggest that SIVsm has infected macaques in captivity and humans in West Africa and evolved as SIVmac and HIV-2, respectively.

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Abstract: Multifactorial mechanisms underlying late-onset Alzheimer's disease (LOAD) are poorly characterized from an integrative perspective. Here spatiotemporal alterations in brain amyloid-β deposition, metabolism, vascular, functional activity at rest, structural properties, cognitive integrity and peripheral proteins levels are characterized in relation to LOAD progression. We analyse over 7,700 brain images and tens of plasma and cerebrospinal fluid biomarkers from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Through a multifactorial data-driven analysis, we obtain dynamic LOAD-abnormality indices for all biomarkers, and a tentative temporal ordering of disease progression. Imaging results suggest that intra-brain vascular dysregulation is an early pathological event during disease development. Cognitive decline is noticeable from initial LOAD stages, suggesting early memory deficit associated with the primary disease factors. High abnormality levels are also observed for specific proteins associated with the vascular system's integrity. Although still subjected to the sensitivity of the algorithms and biomarkers employed, our results might contribute to the development of preventive therapeutic interventions.

International Migration: A Panel Data Analysis of the Determinants of Bilateral Flows

Abstract: In this paper I empirically investigate the determinants of migration inflows into fourteen OECD countries by country of origin, between 1980 and 1995. I analyze the effect on migration of average income and income dispersion in destination and origin countries. I also examine the impact of geographical, cultural, and demographic factors as well as the role played by changes in destination countries' migration policies. My analysis both delivers estimates consistent with the predictions of the international migration model and generates empirical puzzles.