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Paule-Joanne Toussaint

Researcher at Montreal Neurological Institute and Hospital

Publications -  13
Citations -  1045

Paule-Joanne Toussaint is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Computer science & Cognitive decline. The author has an hindex of 5, co-authored 8 publications receiving 743 citations. Previous affiliations of Paule-Joanne Toussaint include Pierre-and-Marie-Curie University.

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Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Yasser Iturria-Medina, +314 more
TL;DR: Imaging results suggest that intra-brain vascular dysregulation is an early pathological event during disease development, suggesting early memory deficit associated with the primary disease factors.
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Resting state FDG-PET functional connectivity as an early biomarker of Alzheimer's disease using conjoint univariate and independent component analyses.

TL;DR: Improved early detection and differentiation of typical versus pathological metabolic patterns in the MCI population is achieved, reaching 80% accuracy (85% sensitivity and 75% specificity) when using selected regions.
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Characteristics of the default mode functional connectivity in normal ageing and Alzheimer's disease using resting state fMRI with a combined approach of entropy-based and graph theoretical measurements.

TL;DR: Investigating functional connectivity within the default mode network (DMN) in normal ageing and AD using resting state fMRI found a decrease in antero-posterior interactions, but increased interactions within the frontal and parietal sub-systems in elderly compared to young controls and in AD patients compared to elderly controls.
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The Open Brain Consent: Informing research participants and obtaining consent to share brain imaging data

Elise Bannier, +38 more
- 01 Feb 2021 - 
TL;DR: Open Brain Consent (http://www.readthedocs.io) is an international initiative that aims to provide researchers in the brain imaging community with information about data sharing options and tools.