Showing papers by "National Institute of Standards and Technology published in 2003"

Face recognition: A literature survey

Abstract: As one of the most successful applications of image analysis and understanding, face recognition has recently received significant attention, especially during the past several years. At least two reasons account for this trend: the first is the wide range of commercial and law enforcement applications, and the second is the availability of feasible technologies after 30 years of research. Even though current machine recognition systems have reached a certain level of maturity, their success is limited by the conditions imposed by many real applications. For example, recognition of face images acquired in an outdoor environment with changes in illumination and/or pose remains a largely unsolved problem. In other words, current systems are still far away from the capability of the human perception system.This paper provides an up-to-date critical survey of still- and video-based face recognition research. There are two underlying motivations for us to write this survey paper: the first is to provide an up-to-date review of the existing literature, and the second is to offer some insights into the studies of machine recognition of faces. To provide a comprehensive survey, we not only categorize existing recognition techniques but also present detailed descriptions of representative methods within each category. In addition, relevant topics such as psychophysical studies, system evaluation, and issues of illumination and pose variation are covered.

Oxidative DNA damage: mechanisms, mutation, and disease

Abstract: Oxidative DNA damage is an inevitable consequence of cellular metabolism, with a propensity for increased levels following toxic insult. Although more than 20 base lesions have been identified, only a fraction of these have received appreciable study, most notably 8-oxo-2'deoxyguanosine. This lesion has been the focus of intense research interest and been ascribed much importance, largely to the detriment of other lesions. The present work reviews the basis for the biological significance of oxidative DNA damage, drawing attention to the multiplicity of proteins with repair activities along with a number of poorly considered effects of damage. Given the plethora of (often contradictory) reports describing pathological conditions in which levels of oxidative DNA damage have been measured, this review critically addresses the extent to which the in vitro significance of such damage has relevance for the pathogenesis of disease. It is suggested that some shortcomings associated with biomarkers, along with gaps in our knowledge, may be responsible for the failure to produce consistent and definitive results when applied to understanding the role of DNA damage in disease, highlighting the need for further studies.

Quantum dynamics of single trapped ions

Abstract: Single trapped ions represent elementary quantum systems that are well isolated from the environment. They can be brought nearly to rest by laser cooling, and both their internal electronic states and external motion can be coupled to and manipulated by light fields. This makes them ideally suited for quantum-optical and quantum-dynamical studies under well-controlled conditions. Theoretical and experimental work on these topics is reviewed in the paper, with a focus on ions trapped in radio-frequency (Paul) traps.

The HITRAN molecular spectroscopic database: edition of 2000 including updates through 2001

Abstract: This paper describes the status circa 2001, of the HITRAN compilation that comprises the public edition available through 2001. The HITRAN compilation consists of several components useful for radiative transfer calculation codes: high-resolution spectroscopic parameters of molecules in the gas phase, absorption cross-sections for molecules with very dense spectral features, aerosol refractive indices, ultraviolet line-by-line parameters and absorption cross-sections, and associated database management software. The line-by-line portion of the database contains spectroscopic parameters for 38 molecules and their isotopologues and isotopomers suitable for calculating atmospheric transmission and radiance properties. Many more molecular species are presented in the infrared cross-section data than in the previous edition, especially the chlorofluorocarbons and their replacement gases. There is now sufficient representation so that quasi-quantitative simulations can be obtained with the standard radiance codes. In addition to the description and justification of new or modified data that have been incorporated since the last edition of HITRAN (1996), future modifications are indicated for cases considered to have a significant impact on remote-sensing experiments. (C) 2003 Elsevier Ltd. All rights reserved.

Optical properties of gold nanorings

Abstract: The optical response of ring-shaped gold nanoparticles prepared by colloidal lithography is investigated. Compared to solid gold particles of similar size, nanorings exhibit a redshifted localized surface plasmon that can be tuned over an extended wavelength range by varying the ratio of the ring thickness to its radius. The measured wavelength variation is well reproduced by numerical calculations and interpreted as originating from coupling of dipolar modes at the inner and outer surfaces of the nanorings. The electric field associated with these plasmons exhibits uniform enhancement and polarization in the ring cavity, suggesting applications in near-infrared surface-enhanced spectroscopy and sensing.

Colloquium: Femtosecond optical frequency combs

Abstract: Recently there has been a remarkable synergy between the technologies of precision laser stabilization and mode-locked ultrafast lasers. This has resulted in control of the frequency spectrum produced by mode-locked lasers, which consists of a regular comb of sharp lines. Thus such a controlled mode-locked laser is a ``femtosecond optical frequency comb generator.'' For a sufficiently broad comb, it is possible to determine the absolute frequencies of all of the comb lines. This ability has revolutionized optical frequency metrology and synthesis. It has also served as the basis for the recent demonstrations of atomic clocks that utilize an optical frequency transition. In addition, it is having an impact on time-domain applications, including synthesis of a single pulse from two independent lasers. In this Colloquium, we first review the frequency-domain description of a mode-locked laser and the connection between the pulse phase and the frequency spectrum in order to provide a basis for understanding how the absolute frequencies can be determined and controlled. Using this understanding, applications in optical frequency metrology and synthesis and optical atomic clocks are discussed. This is followed by a brief overview of how the comb technology is affecting and will affect time-domain experiments.

Emergence of a molecular Bose–Einstein condensate from a Fermi gas

Abstract: The realization of superfluidity in a dilute gas of fermionic atoms, analogous to superconductivity in metals, represents a long-standing goal of ultracold gas research. In such a fermionic superfluid, it should be possible to adjust the interaction strength and tune the system continuously between two limits: a Bardeen–Cooper–Schrieffer (BCS)-type superfluid (involving correlated atom pairs in momentum space) and a Bose–Einstein condensate (BEC), in which spatially local pairs of atoms are bound together. This crossover between BCS-type superfluidity and the BEC limit has long been of theoretical interest, motivated in part by the discovery of high-temperature superconductors1,2,3,4,5,6,7,8,9,10. In atomic Fermi gas experiments superfluidity has not yet been demonstrated; however, long-lived molecules consisting of locally paired fermions have been reversibly created11,12,13,14,13. Here we report the direct observation of a molecular Bose–Einstein condensate created solely by adjusting the interaction strength in an ultracold Fermi gas of atoms. This state of matter represents one extreme of the predicted BCS–BEC continuum.

Experimental demonstration of a robust, high-fidelity geometric two ion-qubit phase gate

Abstract: Universal logic gates for two quantum bits (qubits) form an essential ingredient of quantum computation. Dynamical gates have been proposed in the context of trapped ions; however, geometric phase gates (which change only the phase of the physical qubits) offer potential practical advantages because they have higher intrinsic resistance to certain small errors and might enable faster gate implementation. Here we demonstrate a universal geometric pi-phase gate between two beryllium ion-qubits, based on coherent displacements induced by an optical dipole force. The displacements depend on the internal atomic states; the motional state of the ions is unimportant provided that they remain in the regime in which the force can be considered constant over the extent of each ion's wave packet. By combining the gate with single-qubit rotations, we have prepared ions in an entangled Bell state with 97% fidelity-about six times better than in a previous experiment demonstrating a universal gate between two ion-qubits. The particular properties of the gate make it attractive for a multiplexed trap architecture that would enable scaling to large numbers of ion-qubits.

Experimental demonstration of a robust, high-fidelity geometric two ion-qubit phase gate*

Abstract: Universal logic gates for two quantum bits (qubits) form an essential ingredient of quantum computation. Dynamical gates have been proposed in the context of trapped ions; however, geometric phase gates (which change only the phase of the physical qubits) offer potential practical advantages because they have higher intrinsic resistance to certain small errors and might enable faster gate implementation. Here we demonstrate a universal geometric pi-phase gate between two beryllium ion-qubits, based on coherent displacements induced by an optical dipole force. The displacements depend on the internal atomic states; the motional state of the ions is unimportant provided that they remain in the regime in which the force can be considered constant over the extent of each ion's wave packet. By combining the gate with single-qubit rotations, we have prepared ions in an entangled Bell state with 97% fidelity-about six times better than in a previous experiment demonstrating a universal gate between two ion-qubits. The particular properties of the gate make it attractive for a multiplexed trap architecture that would enable scaling to large numbers of ion-qubits.

Update of the AAPM task group no. 43 report - a revised AAPM protocol for brachytherapy dose calculations

Abstract: Since publication of the American Association of Physicists in Medicine (AAPM) Task Group No. 43 Report in 1995 (TG-43), both the utilization of permanent source implantation and the number of low-energy interstitial brachytherapy source models commercially available have dramatically increased. In addition, the National Institute of Standards and Technology has introduced a new primary standard of air-kerma strength, and the brachytherapy dosimetry literature has grown substantially, documenting both improved dosimetry methodologies and dosimetric characterization of particular source models. In response to these advances, the AAPM Low-energy Interstitial Brachytherapy Dosimetry subcommittee (LIBD) herein presents an update of the TG-43 protocol for calculation of dose-rate distributions around photon-emitting brachytherapy sources. The updated protocol (TG-43U1) includes (a) a revised definition of air-kerma strength; (b) elimination of apparent activity for specification of source strength; (c) elimination of the anisotropy constant in favor of the distance-dependent one-dimensional anisotropy function; (d) guidance on extrapolating tabulated TG-43 parameters to longer and shorter distances; and (e) correction for minor inconsistencies and omissions in the original protocol and its implementation. Among the corrections are consistent guidelines for use of point- and line-source geometry functions. In addition, this report recommends a unified approach to comparing reference dose distributions derived from different investigators to develop a single critically evaluated consensus dataset as well as guidelines for performing and describing future theoretical and experimental single-source dosimetry studies. Finally, the report includes consensus datasets, in the form of dose-rate constants, radial dose functions, and one-dimensional (1D) and two-dimensional (2D) anisotropy functions, for all low-energy brachytherapy source models that met the AAPM dosimetric prerequisites [Med. Phys. 25, 2269 (1998)] as of July 15, 2001. These include the following 125I sources: Amersham Health models 6702 and 6711, Best Medical model 2301, North American Scientific Inc. (NASI) model MED3631-A/M, Bebig/Theragenics model I25.S06, and the Imagyn Medical Technologies Inc. isostar model IS-12501. The 103Pd sources included are the Theragenics Corporation model 200 and NASI model MED3633. The AAPM recommends that the revised dose-calculation protocol and revised source-specific dose-rate distributions be adopted by all end users for clinical treatment planning of low energy brachytherapy interstitial sources. Depending upon the dose-calculation protocol and parameters currently used by individual physicists, adoption of this protocol may result in changes to patient dose calculations. These changes should be carefully evaluated and reviewed with the radiation oncologist preceding implementation of the current protocol.

Creation of ultracold molecules from a Fermi gas of atoms

Abstract: Following the realization of Bose–Einstein condensates in atomic gases, an experimental challenge is the production of molecular gases in the quantum regime. A promising approach is to create the molecular gas directly from an ultracold atomic gas; for example, bosonic atoms in a Bose-Einstein condensate have been coupled to electronic ground-state molecules through photoassociation1 or a magnetic field Feshbach resonance2. The availability of atomic Fermi gases offers the prospect of coupling fermionic atoms to bosonic molecules, thus altering the quantum statistics of the system. Such a coupling would be closely related to the pairing mechanism in a fermionic superfluid, predicted to occur near a Feshbach resonance3,4. Here we report the creation and quantitative characterization of ultracold 40K2 molecules. Starting with a quantum degenerate Fermi gas of atoms at a temperature of less than 150 nK, we scan the system over a Feshbach resonance to create adiabatically more than 250,000 trapped molecules; these can be converted back to atoms by reversing the scan. The small binding energy of the molecules is controlled by detuning the magnetic field away from the Feshbach resonance, and can be varied over a wide range. We directly detect these weakly bound molecules through their radio-frequency photodissociation spectra; these probe the molecular wavefunction, and yield binding energies that are consistent with theory.

Averaged transition conditions for electromagnetic fields at a metafilm

Abstract: This paper derives generalized sheet transition conditions (GSTCs) for the average electromagnetic fields across a surface distribution of electrically small scatterers characterized by electric and magnetic polarization densities. We call such an arrangement of scatterers a metafilm-the two-dimensional (2-D) equivalent of a metamaterial. The derivation is based on a replacement of the discrete distribution of scatterers by a continuous one, resulting in a continuous distribution of electric and magnetic polarization densities in the surface. This is done in a manner analogous to the Clausius-Mossotti-Lorenz-Lorentz procedure for determining the dielectric constant of a volume distribution of small scatterers. The result contains as special cases many particular ones found throughout the literature. The GSTCs are expected to have wide application to the design and analysis of antennas, reflectors, and other devices where controllable scatterers are used to form a "smart" surface.

Characterization of Polymer-Layered Silicate (Clay) Nanocomposites by Transmission Electron Microscopy and X-Ray Diffraction: A Comparative Study

Abstract: Several polymer-layered silicate (clay) nano- composites (PLSNs) were analyzed by transmission electron microscopy (TEM) and wide-angle X-ray diffraction (XRD) in an effort to characterize the nanoscale dispersion of the layered silicate. The PLSNs investigated included thermoset (cyanate esters) and thermoplastic polymers (polystyrene, nylon 6, and polypropylene-g-maleic anhydride). The re- sults of this study reveal that the overall nanoscale disper- sion of the clay in the polymer is best described by TEM, especially when mixed morphologies are present. XRD is useful for the measurement of d-spacings in intercalated systems but cannot always observe low clay loadings (5%) or be used as a method to identify an exfoliated nanocom- posite where no XRD peaks are present (constituting a neg- ative result). Most importantly, the study showed that XRD is not a stand-alone technique, and it should be used in conjunction with TEM. Our studies suggest that new defi- nitions, or a clarification of existing definitions, are needed to properly describe the diversity of PLSN nanostructures seen in various materials. © 2002 Wiley Periodicals, Inc.* J Appl Polym Sci 87: 1329 -1338, 2003

Nanoscale effects leading to non-Einstein-like decrease in viscosity

Abstract: Nanoparticles have been shown to influence mechanical properties; however, transport properties such as viscosity have not been adequately studied. This might be due to the common observation that particle addition to liquids produces an increase in viscosity, even in polymeric liquids, as predicted by Einstein nearly a century ago. But confinement and surface effects provided by nanoparticles have been shown to produce conformational changes to polymer molecules, so it is expected that nanoparticles will affect the macroscopic viscosity. To minimize extraneous enthalpic or other effects, we blended organic nanoparticles, synthesized by intramolecular crosslinking of single polystyrene chains, with linear polystyrene macromolecules. Remarkably, the blend viscosity was found to decrease and scale with the change in free volume introduced by the nanoparticles and not with the decrease in entanglement. Indeed, the entanglements did not seem to be affected at all, suggesting unusual polymer dynamics.

NIST Net: a Linux-based network emulation tool

Abstract: Testing of network protocols and distributed applications has become increasingly complex, as the diversity of networks and underlying technologies increase, and the adaptive behavior of applications becomes more sophisticated. In this paper, we present NIST Net, a tool to facilitate testing and experimentation with network code through emulation. NIST Net enables experimenters to model and effect arbitrary performance dynamics (packet delay, jitter, bandwidth limitations, congestion, packet loss and duplication) on live IP packets passing through a commodity Linux-based PC router. We describe the emulation capabilities of NIST Net; examine its architecture; and discuss some of the implementation challenges encountered in building such a tool to operate at very high network data rates while imposing minimal processing overhead. Calibration results are provided to quantify the fidelity and performance of NIST Net over a wide range of offered loads (up to 1 Gbps), and a diverse set of emulated performance dynamics.

X-ray transition energies: new approach to a comprehensive evaluation

Abstract: The authors combine modern theoretical calculations with evaluated selected experimental data to produce a comprehensive data resource of K- and L-x-ray transition and absorption edge energies for all of the elements from neon to fermium. The theoretical and experimental components of this work are the result of programs of parallel development extending over more than 20 years. At each of several progressively more refined comparisons, it was possible to identify theoretical components whose systematic improvement then led to the next level of refinement in comparisons with an increasingly robust experimental reference data set. We have now reached a certain practical limit in what can be undertaken with reasonable levels of theoretical effort. This limit is not very different from the practical level of accuracy that can be meaningfully associated with the experimental data. For the more prominent diagram lines, experiment and theory are concordant with a zero-centered distribution of residuals whose statistical metrics allow the uncertainties to be estimated. For the light elements $(Zl20)$ and the very heavy elements $(Zg90)$ there are significant difficulties, as is also the case for a few isolated elements and transitions for $20lZl90.$ Overall, the results reported here represent improvements over previously available data compilations not only because of their scope but also because of their attempt to offer internal metrics of the database accuracy. The identified regions of difficulty are areas where further experimental work may be directed to see if there may remain theoretical issues that are still unresolved.

The development of reduced size STR amplicons as tools for analysis of degraded DNA.

Abstract: New multiplex PCR sets of commonly used short tandem repeat (STR) markers have been developed to produce PCR products that are reduced in size when compared to standard commercial STR kits. The reduction in size of these amplicons can facilitate the examination and analysis of degraded DNA evidence by improving amplification efficiency. This "miniSTR" approach will permit current forensic practitioners to use STR markers and instrumentation already present in their laboratories and to generate genotyping data that is directly comparable to reference samples and searchable through the FBI's Combined DNA Index System (CODIS) databases. This paper discusses the development of these new primer sets and presents some initial results in the analysis of degraded and aged DNA samples. A method for removal of problematic fluorescent dye artifacts is also described. Comparison studies in over 100 samples have verified that these miniSTR primers can provide fully concordant results to commercial STR kits and can provide improved signal from degraded DNA specimens. These miniplex sets should prove valuable in the analysis of samples where allele dropout and reduced sensitivity of larger STR alleles occurs.

NIST Digital Library of Mathematical Functions

Abstract: The National Institute of Standards and Technology is preparing a Digital Library of Mathematical Functions (DLMF) to provide useful data about special functions for a wide audience. The initial products will be a published handbook and companion Web site, both scheduled for completion in 2003. More than 50 mathematicians, physicists and computer scientists from around the world are participating in the work. The data to be covered include mathematical formulas, graphs, references, methods of computation, and links to software. Special features of the Web site include 3D interactive graphics and an equation search capability. The information technology tools that are being used are, of necessity, ones that are widely available now, even though better tools are in active development. For example, LaTeX files are being used as the common source for both the handbook and the Web site. This is the technology of choice for presentation of mathematics in print but it is not well suited to equation search, for example, or for input to computer algebra systems. These and other problems, and some partially successful work-arounds, are discussed in this paper and in the companion paper by Miller and Youssef.

Base-dependent competitive adsorption of single-stranded DNA on gold.

Abstract: We characterize the room-temperature adsorption of single-stranded DNA homo-oligonucleotides from solution onto polycrystalline Au films, including competitive adsorption between all possible pairs of unmodified oligomers. Fourier transform infrared (FTIR) and X-ray photoelectron (XPS) spectroscopy analysis of the resulting films shows that oligonucleotides adsorb with a strongly base-dependent affinity, adenine (A) > cytosine (C) ≥ guanine (G) > thymine (T). In competitive adsorption experiments on Au, oligo(dA) strongly dominates over the other oligonucleotides. The relative adsorption affinity of oligo(dA) is so great that it competes effectively against adsorption of thiolated oligomers and even causes hybridized oligo(dA)·oligo(dT) duplexes to denature in the presence of Au.

Review of Instrumented Indentation

Abstract: Instrumented indentation, also known as depth-sensing indentation or nanoindentation, is increasingly being used to probe the mechanical response of materials from metals and ceramics to polymeric and biological materials. The additional levels of control, sensitivity, and data acquisition offered by instrumented indentation systems have resulted in numerous advances in materials science, particularly regarding fundamental mechanisms of mechanical behavior at micrometer and even sub-micrometer length scales. Continued improvements of instrumented indentation testing towards absolute quantification of a wide range of material properties and behavior will require advances in instrument calibration, measurement protocols, and analysis tools and techniques. In this paper, an overview of instrumented indentation is given with regard to current instrument technology and analysis methods. Research efforts at the National Institute of Standards and Technology (NIST) aimed at improving the related measurement science are discussed.

Durability Gap Analysis for Fiber-Reinforced Polymer Composites in Civil Infrastructure

Abstract: The lack of a comprehensive, validated, and easily accessible data base for the durability of fiber-reinforced polymer (FRP) composites as related to civil infrastructure applications has been identified as a critical barrier to widespread acceptance of these materials by structural designers and civil engineers. This concern is emphasized since the structures of interest are primarily load bearing and are expected to remain in service over extended periods of time without significant inspection or maintenance. This paper presents a synopsis of a gap analysis study undertaken under the aegis of the Civil Engineering Research Foundation and the Federal Highway Administration to identify and prioritize critical gaps in durability data. The study focuses on the use of FRP in internal reinforcement, external strengthening, seismic retrofit, bridge decks, structural profiles, and panels. Environments of interest are moisture/solution, alkalinity, creep/relaxation, fatigue, fire, thermal effects (including free...

A double negative (DNG) composite medium composed of magnetodielectric spherical particles embedded in a matrix

Abstract: We study a composite medium consisting of insulating magnetodielectric spherical particles embedded in a background matrix. Using results from the literature going back as far as Lewin (1947), we show that the effective permeability and permittivity of the mixture can be simultaneously negative for wavelengths where the spherical inclusions are resonant and that the medium results in an effective "double negative (DNG) media". Materials of this type are also called negative-index materials, backward media (BW), and left-handed materials. This type of material belongs to a more general class of metamaterials. The theoretical results presented here show that composite media having much simpler structure than those reported in the literature can exhibit negative permeability and permittivity over significant bandwidths.

Face recognition vendor test 2002

Abstract: Summary form only given. The face recognition vendor test (FRVT) 2002 is an independently administered technology evaluation of mature face recognition systems. FRVT 2002 provides performance measures for assessing the capability of face recognition systems to meet requirements for large-scale, real-world applications. Participation in FRVT 2002 was open to commercial and mature prototype systems from universities, research institutes, and companies. Ten companies submitted either commercial or prototype systems. FRVT 2002 computed performance statistics on an extremely large data set-121,589 operational facial images of 37,437 individuals. FRVT 2002 1) characterized identification and watch list performance as a function of database size, 2) estimated the variability in performance for different groups of people, 3) characterized performance as a function of elapsed time between enrolled and new images of a person, and 4) investigated the effect of demographics on performance. FRVT 2002 showed that recognition from indoor images has made substantial progress since FRVT 2000. Demographic results show that males are easier to recognize than females and that older people are easier to recognize than younger people. FRVT 2002 also assessed the impact of three new techniques for improving face recognition: three-dimensional morphable models, normalization of similarity scores, and face recognition from video sequences. Results show that three-dimensional morphable models and normalization increase performance and that face recognition from video sequences offers only a limited increase in performance over still images. A new XML-based evaluation protocol was developed for FRVT 2002. This protocol is flexible and supports evaluations of biometrics in general The FRVT 2002 reports can be found at http://www.frvt.org.

Spatially heterogeneous dynamics investigated via a time-dependent four-point density correlation function

Abstract: Relaxation in supercooled liquids above their glass transition and below the onset temperature of “slow” dynamics involves the correlated motion of neighboring particles This correlated motion results in the appearance of spatially heterogeneous dynamics or “dynamical heterogeneity” Traditional two-point time-dependent density correlation functions, while providing information about the transient “caging” of particles on cooling, are unable to provide sufficiently detailed information about correlated motion and dynamical heterogeneity Here, we study a four-point, time-dependent density correlation function g4(r,t) and corresponding “structure factor” S4(q,t) which measure the spatial correlations between the local liquid density at two points in space, each at two different times, and so are sensitive to dynamical heterogeneity We study g4(r,t) and S4(q,t) via molecular dynamics simulations of a binary Lennard-Jones mixture approaching the mode coupling temperature from above We find that the correl

Stability of Interrupted Cutting by Temporal Finite Element Analysis

Abstract: Chatter in milling and other interrupted cutting operations occurs at different combinations of speed and depth of cut from chatter in continuous cutting. Prediction of stability in interrupted cutting is complicated by two facts: (1) the equation of motion when cutting is not the same as the equation when the tool is free; (2) no exact analytical solution is known when the tool is in the cut. These problems are overcome by matching the free response with an approximate solution that is valid white the tool is cutting. An approximate solution, not restricted to small times in the cut, is obtained by the application of finite elements in time. The complete, combined solution is cast in the form of a discrete map that relates position and velocity at the beginning and end of each element to the corresponding values one period earlier. The eigenvalues of the linearized map are used to determine stability. This method can be used to predict stability for arbitrary times in the cut; the current method is applicable only to a single degree of freedom. Predictions of stability for a 1-degree of freedom case are confirmed by experiment.

Fundamental noise limitations to supercontinuum generation in microstructure fiber.

Abstract: Broadband noise on supercontinuum spectra generated in microstructure fiber is shown to lead to amplitude fluctuations as large as 50% for certain input laser pulse parameters. We study this noise using both experimental measurements and numerical simulations with a generalized stochastic nonlinear Schrodinger equation, finding good quantitative agreement over a range of input-pulse energies and chirp values. This noise is shown to arise from nonlinear amplification of two quantum noise inputs: the input-pulse shot noise and the spontaneous Raman scattering down the fiber.

Quantitative Analysis and Characterization of DNA Immobilized on Gold

Abstract: We describe the complementary use of X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FTIR) spectroscopy to quantitatively characterize the immobilization of thiolated (dT)(25) single-stranded DNA (ssDNA) on gold. When electron attenuation effects are accurately accounted for in the XPS analysis, the relative coverage values obtained by the two methods are in excellent agreement, and the absolute coverage can be calculated on the basis of the XPS data. The evolution of chemically specific spectral signatures during immobilization indicates that at lower coverages much of the DNA lies flat on the surface, with a substantial fraction of the thymine bases chemisorbed. At higher immobilization densities, the (dT)(25) film consists of randomly coiled ssDNA molecules each anchored via the thiol group and at possibly one or two other bases. We use two examples to demonstrate how the quantitative analysis can be applied to practical problems: the effects of different buffer salts on the immobilization efficiency; the immobilization kinetics. Buffers with divalent salts dramatically increase the efficiency of immobilization and result in very high surface densities (>5 x 10(13)/ cm(2)), densities that may only be possible if the divalent counterions induce strong attractive intermolecular interactions. In contrast with previous reports of alkanethiol adsorption kinetics on gold, ssDNA immobilization in 1 M phosphate buffer does not occur with Langmuir kinetics, a result attributable to rearrangement within the film that follows the initial adsorption.

Calculation of electron inelastic mean free paths (IMFPs) VII. Reliability of the TPP-2M IMFP predictive equation †

Abstract: from the two sources and for which optical data were available for the IMFP calculations. The average of the root-mean-square (RMS) deviations for the ten materials between IMFPs from the TPP-2M equation with our Nv values and the reference IMFPs was 11.0%, whereas the corresponding average with the Seah et al. Nv values was 20.2%. The larger average in the latter comparison was mainly due to large (>20%) RMS deviations for four materials (K, Hf, Ta and KBr). For the other six materials, the RMS deviations with the Seah et al .v alues ofNv were similar to those with our values of Nv. Based on the comparisons for these ten materials, we believe that it is preferable to use our values of Nv in the TPP-2M equation. Copyright  2003 John Wiley & Sons, Ltd.