Open University of Catalonia

About: Open University of Catalonia is a education organization based out in Barcelona, Spain. It is known for research contribution in the topics: Context (language use) & Higher education. The organization has 1943 authors who have published 4646 publications receiving 64200 citations. The organization is also known as: Universitat Oberta de Catalunya & UOC.

Teletrabajo y vida cotidiana: Ventajas y dificultades para la conciliación de la vida laboral, personal y familiar

Abstract: In this article we discuss whether telework constitutes a useful work-life balance strategy for women teleworkers with dependants. From our analysis we show that the discourse of the women interviewed about telework is not homogeneous, compact or linear, but includes plenty of contradictions, paradoxes and tensions. This fact reinforces telework’s enormous polysemy: it liberates and enslaves, it is a trap and an opportunity, it fulfills and can mean self-sacrifice. But, despite this rich complexity, our women informants agree on one particular matter: telework’s risks and possibly pernicious effects cannot hide either its advantages for work-life balance or the benefits it brings, at least in some cases, to one's personal life.

When sustainable may not mean just: a critical interpretation of urban water consumption decline in Barcelona

Abstract: In this paper, we document and analyse the recent decline (2007–2013) in domestic water consumption in Barcelona. The postulates of ecological modernisation and market environmentalism celebrate these declines as an example of sustainable development, thanks to the combination of more efficient technologies and economic incentives. However, these interpretations ignore the new framework of social relations introduced by technologies and markets and take environmental improvements as homogeneous and universal regardless of distributional issues. Therefore, it would be perfectly possible to achieve optimal environmental situations in the context of deteriorating social conditions, particularly in terms of access to basic resources by the most disadvantaged. We explored the relationships between declining domestic water consumption and the uneven impact of the economic crisis on Barcelona’s urban geography. We found that the alleged increase in environmental sustainability that follows decline in res...

Understanding the response to endurance exercise using a systems biology approach: combining blood metabolomics, transcriptomics and miRNomics in horses.

Abstract: Endurance exercise in horses requires adaptive processes involving physiological, biochemical, and cognitive-behavioral responses in an attempt to regain homeostasis. We hypothesized that the identification of the relationships between blood metabolome, transcriptome, and miRNome during endurance exercise in horses could provide significant insights into the molecular response to endurance exercise. For this reason, the serum metabolome and whole-blood transcriptome and miRNome data were obtained from ten horses before and after a 160 km endurance competition. We obtained a global regulatory network based on 11 unique metabolites, 263 metabolic genes and 5 miRNAs whose expression was significantly altered at T1 (post- endurance competition) relative to T0 (baseline, pre-endurance competition). This network provided new insights into the cross talk between the distinct molecular pathways (e.g. energy and oxygen sensing, oxidative stress, and inflammation) that were not detectable when analyzing single metabolites or transcripts alone. Single metabolites and transcripts were carrying out multiple roles and thus sharing several biochemical pathways. Using a regulatory impact factor metric analysis, this regulatory network was further confirmed at the transcription factor and miRNA levels. In an extended cohort of 31 independent animals, multiple factor analysis confirmed the strong associations between lactate, methylene derivatives, miR-21-5p, miR-16-5p, let-7 family and genes that coded proteins involved in metabolic reactions primarily related to energy, ubiquitin proteasome and lipopolysaccharide immune responses after the endurance competition. Multiple factor analysis also identified potential biomarkers at T0 for an increased likelihood for failure to finish an endurance competition. To the best of our knowledge, the present study is the first to provide a comprehensive and integrated overview of the metabolome, transcriptome, and miRNome co-regulatory networks that may have a key role in regulating the metabolic and immune response to endurance exercise in horses.