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Institution

Research Triangle Park

NonprofitDurham, North Carolina, United States
About: Research Triangle Park is a nonprofit organization based out in Durham, North Carolina, United States. It is known for research contribution in the topics: Population & Receptor. The organization has 24961 authors who have published 35800 publications receiving 1684504 citations. The organization is also known as: RTP.


Papers
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Journal ArticleDOI
TL;DR: The GSK solvent selection guide has been further enhanced by as discussed by the authors, with more than doubling the number of solvents in the guide, to a total of 110 from the initial 47.

842 citations

Journal ArticleDOI
TL;DR: To determine a standard for infants delivered at about sea level the 10th, 25th, 50th, 75th, and 90th percentiles of fetal weight for each menstrual week of gestation were calculated from 430 fetuses at 8 to 20 menstrual weeks' gestation aborted with prostaglandins.

835 citations

Journal ArticleDOI
TL;DR: A DNA sequence database that includes a 500–base pair region of the HBV polymerase gene from 20 patients with clinical manifestations of lamivudine resistance is reported, revealing two patterns of amino acid substitutions in the tyrosine, methionine, as partate, aspartate (YMDD) nucleotide‐binding locus of theHBV polymerases.

827 citations

Journal ArticleDOI
TL;DR: This work has shown thatgenic animals suggest a complex role for NF-κB family members in immunity and development and interacts with multiple transcription factors and transcriptional co-factors.
Abstract: I. Introduction II. Nuclear Factor-κB (NF-κB) A. Introduction B. NF-κB is a dimeric transcription factor C. The regulatory subunit IκB is an inhibitor of NF-κB D. Activation and function of NF-κB E. The transcription factor NF-κB interacts with multiple transcription factors and transcriptional co-factors F. Transgenic animals suggest a complex role for NF-κB family members in immunity and development III. Steroid Hormones/Receptors: Glucocorticoids and the Glucocorticoid Receptor (GR) A. General background B. Glucocorticoid mechanism of action: the GR C. Glucocorticoid physiology D. GR/NF-κB interactions E. GR interacts with other transcription factors and transcriptional cofactors IV. NF-κB and GR Antagonism: Physiological Significance? V. Interactions Between NF-κB and Other Steroid Hormone Receptors A. Androgen receptor (AR) B. Estrogen receptor (ER) C. Progesterone receptor (PR) VI. Summary/Conclusions

826 citations

Journal ArticleDOI
TL;DR: The potency and selectivity of 1400W inhibition of iNOS both in vitro and in vivo were far greater than of any previously described iN OS inhibitor.

825 citations


Authors

Showing all 25006 results

NameH-indexPapersCitations
Douglas G. Altman2531001680344
Lewis C. Cantley196748169037
Ronald Klein1941305149140
Daniel J. Jacob16265676530
Christopher P. Cannon1511118108906
James B. Meigs147574115899
Lawrence Corey14677378105
Jeremy K. Nicholson14177380275
Paul M. Matthews14061788802
Herbert Y. Meltzer137114881371
Charles J. Yeo13667276424
Benjamin F. Cravatt13166661932
Timothy R. Billiar13183866133
Peter Brown12990868853
King K. Holmes12460656192
Network Information
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202317
202277
2021988
20201,001
20191,035
20181,051