Institution
Research Triangle Park
Nonprofit•Durham, North Carolina, United States•
About: Research Triangle Park is a nonprofit organization based out in Durham, North Carolina, United States. It is known for research contribution in the topics: Population & Receptor. The organization has 24961 authors who have published 35800 publications receiving 1684504 citations. The organization is also known as: RTP.
Topics: Population, Receptor, Health care, Gene, Environmental exposure
Papers published on a yearly basis
Papers
More filters
TL;DR: CLA is a high affinity ligand and activator of peroxisome proliferator-activated receptor alpha (PPARalpha) and induces accumulation of PPAR-responsive mRNAs in a rat hepatoma cell line and its effects on lipid metabolism may be attributed to transcriptional events associated with this nuclear receptor.
403 citations
TL;DR: It is reported that CAR and PXR activators differentially regulated the expression of several genes, demonstrating that these two nuclear receptors subserve overlapping but distinct biological functions in human hepatocytes.
403 citations
TL;DR: The degree of inequality in the levels of well-being of its citizens tells us a great deal about a society and enables us to judge its social and economic system, identify those citizens with a claim on community compassion, to identify the sources of hardship, and to devise strategies for reducing levels of hardship.
Abstract: The degree of inequality in the levels of well-being of its citizens tells us a great deal about a society It enables us to judge its social and economic system, to identify those citizens with a claim on community compassion, to identify the sources of hardship, and to devise strategies for reducing levels of hardship The value of such information is undoubted But we confront a severe practical problem in first defining, and then measuring, what we mean by well-being It is surely multi-dimensional, and difficult to reduce to a scalar-valued index
403 citations
TL;DR: In this paper, the dissociation rate constants for WT, G48V, and L90M/G48V proteases complexed with saquinavir were 0.019, 0.128, and 0.54 s−1, respectively.
402 citations
TL;DR: In this paper, the authors performed a retrospective medical review of pooled adverse events data from ∼200,000 patients who received abacavir in clinical trials, through expanded-access programs, or by prescription from 1996 through 2000.
402 citations
Authors
Showing all 25006 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Douglas G. Altman | 253 | 1001 | 680344 |
| Lewis C. Cantley | 196 | 748 | 169037 |
| Ronald Klein | 194 | 1305 | 149140 |
| Daniel J. Jacob | 162 | 656 | 76530 |
| Christopher P. Cannon | 151 | 1118 | 108906 |
| James B. Meigs | 147 | 574 | 115899 |
| Lawrence Corey | 146 | 773 | 78105 |
| Jeremy K. Nicholson | 141 | 773 | 80275 |
| Paul M. Matthews | 140 | 617 | 88802 |
| Herbert Y. Meltzer | 137 | 1148 | 81371 |
| Charles J. Yeo | 136 | 672 | 76424 |
| Benjamin F. Cravatt | 131 | 666 | 61932 |
| Timothy R. Billiar | 131 | 838 | 66133 |
| Peter Brown | 129 | 908 | 68853 |
| King K. Holmes | 124 | 606 | 56192 |