Institution
Research Triangle Park
Nonprofit•Durham, North Carolina, United States•
About: Research Triangle Park is a nonprofit organization based out in Durham, North Carolina, United States. It is known for research contribution in the topics: Population & Receptor. The organization has 24961 authors who have published 35800 publications receiving 1684504 citations. The organization is also known as: RTP.
Topics: Population, Receptor, Health care, Gene, Environmental exposure
Papers published on a yearly basis
Papers
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TL;DR: A novel synthetic chemical, benzo(1,2,3)thiadiazole-7-carbothioic acid S-methyl ester (BTH), was shown to induce acquired resistance in wheat and was the most potent inducer of both resistance and gene induction.
Abstract: Systemic acquired resistance is an important component of the disease resistance repertoire of plants. In this study, a novel synthetic chemical, benzo(1,2,3)thiadiazole-7-carbothioic acid S-methyl ester (BTH), was shown to induce acquired resistance in wheat. BTH protected wheat systemically against powdery mildew infection by affecting multiple steps in the life cycle of the pathogen. The onset of resistance was accompanied by the induction of a number of newly described wheat chemically induced (WCI) genes, including genes encoding a lipoxygenase and a sulfur-rich protein. With respect to both timing and effectiveness, a tight correlation existed between the onset of resistance and the induction of the WCI genes. Compared with other plant activators, such as 2,6-dichloroisonicotinic acid and salicylic acid, BTH was the most potent inducer of both resistance and gene induction. BTH is being developed commercially as a novel type of plant protection compound that works by inducing the plant's inherent disease resistance mechanisms.
1,120 citations
TL;DR: Chronic pain, experienced by about a third of the population, was correlated with indicators of poorer socioeconomic status and low household income and unemployment as significant socioeconomic correlates of chronic pain.
1,119 citations
TL;DR: The authors used a regression framework and nationally representative data to compute aggregate overweight- and obesity-attributable medical spending for the United States and for select payers, and found that such expenditures accounted for 9.1 percent of total annual U.S. medical expenditures in 1998 and may have been as high as dollar 78.5 billion (dollar 92.6 billion in 2002 dollars).
Abstract: We use a regression framework and nationally representative data to compute aggregate overweight- and obesity-attributable medical spending for the United States and for select payers. Combined, such expenditures accounted for 9.1 percent of total annual U.S. medical expenditures in 1998 and may have been as high as dollar 78.5 billion (dollar 92.6 billion in 2002 dollars). Medicare and Medicaid finance approximately half of these costs.
1,118 citations
TL;DR: The peroxisome proliferator-activated receptors (PPARs) are nuclear receptors for fatty acids (FAs) that regulate glucose and lipid homeostasis as mentioned in this paper.
1,110 citations
TL;DR: Subgroup analyses suggest the risk may be greater in African Americans compared with Caucasian subjects and whether this risk is due to factors including but not limited to a physiologic treatment effect, genetic factors, or patient behaviors leading to poor outcomes remains unknown.
1,108 citations
Authors
Showing all 25006 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Douglas G. Altman | 253 | 1001 | 680344 |
| Lewis C. Cantley | 196 | 748 | 169037 |
| Ronald Klein | 194 | 1305 | 149140 |
| Daniel J. Jacob | 162 | 656 | 76530 |
| Christopher P. Cannon | 151 | 1118 | 108906 |
| James B. Meigs | 147 | 574 | 115899 |
| Lawrence Corey | 146 | 773 | 78105 |
| Jeremy K. Nicholson | 141 | 773 | 80275 |
| Paul M. Matthews | 140 | 617 | 88802 |
| Herbert Y. Meltzer | 137 | 1148 | 81371 |
| Charles J. Yeo | 136 | 672 | 76424 |
| Benjamin F. Cravatt | 131 | 666 | 61932 |
| Timothy R. Billiar | 131 | 838 | 66133 |
| Peter Brown | 129 | 908 | 68853 |
| King K. Holmes | 124 | 606 | 56192 |