Showing papers by "Universidade Federal de Santa Catarina published in 2016"

A century of trends in adult human height

Abstract: Being taller is associated with enhanced longevity, and higher education and earnings. We reanalysed 1472 population-based studies, with measurement of height on more than 18.6 million participants to estimate mean height for people born between 1896 and 1996 in 200 countries. The largest gain in adult height over the past century has occurred in South Korean women and Iranian men, who became 20.2 cm (95% credible interval 17.5–22.7) and 16.5 cm (13.3–19.7) taller, respectively. In contrast, there was little change in adult height in some sub-Saharan African countries and in South Asia over the century of analysis. The tallest people over these 100 years are men born in the Netherlands in the last quarter of 20th century, whose average heights surpassed 182.5 cm, and the shortest were women born in Guatemala in 1896 (140.3 cm; 135.8–144.8). The height differential between the tallest and shortest populations was 19-20 cm a century ago, and has remained the same for women and increased for men a century later despite substantial changes in the ranking of countries.

Fungal diversity notes 111–252—taxonomic and phylogenetic contributions to fungal taxa

Abstract: Notes on 113 fungal taxa are compiled in this paper, including 11 new genera, 89 new species, one new subspecies, three new combinations and seven reference specimens. A wide geographic and taxonomic range of fungal taxa are detailed. In the Ascomycota the new genera Angustospora (Testudinaceae), Camporesia (Xylariaceae), Clematidis, Crassiparies (Pleosporales genera incertae sedis), Farasanispora, Longiostiolum (Pleosporales genera incertae sedis), Multilocularia (Parabambusicolaceae), Neophaeocryptopus (Dothideaceae), Parameliola (Pleosporales genera incertae sedis), and Towyspora (Lentitheciaceae) are introduced. Newly introduced species are Angustospora nilensis, Aniptodera aquibella, Annulohypoxylon albidiscum, Astrocystis thailandica, Camporesia sambuci, Clematidis italica, Colletotrichum menispermi, C. quinquefoliae, Comoclathris pimpinellae, Crassiparies quadrisporus, Cytospora salicicola, Diatrype thailandica, Dothiorella rhamni, Durotheca macrostroma, Farasanispora avicenniae, Halorosellinia rhizophorae, Humicola koreana, Hypoxylon lilloi, Kirschsteiniothelia tectonae, Lindgomyces okinawaensis, Longiostiolum tectonae, Lophiostoma pseudoarmatisporum, Moelleriella phukhiaoensis, M. pongdueatensis, Mucoharknessia anthoxanthi, Multilocularia bambusae, Multiseptospora thysanolaenae, Neophaeocryptopus cytisi, Ocellularia arachchigei, O. ratnapurensis, Ochronectria thailandica, Ophiocordyceps karstii, Parameliola acaciae, P. dimocarpi, Parastagonospora cumpignensis, Pseudodidymosphaeria phlei, Polyplosphaeria thailandica, Pseudolachnella brevifusiformis, Psiloglonium macrosporum, Rhabdodiscus albodenticulatus, Rosellinia chiangmaiensis, Saccothecium rubi, Seimatosporium pseudocornii, S. pseudorosae, Sigarispora ononidis and Towyspora aestuari. New combinations are provided for Eutiarosporella dactylidis (sexual morph described and illustrated) and Pseudocamarosporium pini. Descriptions, illustrations and / or reference specimens are designated for Aposphaeria corallinolutea, Cryptovalsa ampelina, Dothiorella vidmadera, Ophiocordyceps formosana, Petrakia echinata, Phragmoporthe conformis and Pseudocamarosporium pini. The new species of Basidiomycota are Agaricus coccyginus, A. luteofibrillosus, Amanita atrobrunnea, A. digitosa, A. gleocystidiosa, A. pyriformis, A. strobilipes, Bondarzewia tibetica, Cortinarius albosericeus, C. badioflavidus, C. dentigratus, C. duboisensis, C. fragrantissimus, C. roseobasilis, C. vinaceobrunneus, C. vinaceogrisescens, C. wahkiacus, Cyanoboletus hymenoglutinosus, Fomitiporia atlantica, F. subtilissima, Ganoderma wuzhishanensis, Inonotus shoreicola, Lactifluus armeniacus, L. ramipilosus, Leccinum indoaurantiacum, Musumecia alpina, M. sardoa, Russula amethystina subp. tengii and R. wangii are introduced. Descriptions, illustrations, notes and / or reference specimens are designated for Clarkeinda trachodes, Dentocorticium ussuricum, Galzinia longibasidia, Lentinus stuppeus and Leptocorticium tenellum. The other new genera, species new combinations are Anaeromyces robustus, Neocallimastix californiae and Piromyces finnis from Neocallimastigomycota, Phytophthora estuarina, P. rhizophorae, Salispina, S. intermedia, S. lobata and S. spinosa from Oomycota, and Absidia stercoraria, Gongronella orasabula, Mortierella calciphila, Mucor caatinguensis, M. koreanus, M. merdicola and Rhizopus koreanus in Zygomycota.

Identification and analysis of reverse logistics barriers using fuzzy Delphi method and AHP

Abstract: The environmental consciousness of customers and the emergence of stricter environmental regulations has pushed industries to think about environmental management by means of reverse logistics (RL) implementation. In order to implement RL systems, a careful analysis of barriers that hinder the reverse flow must be taken. However, most existing research on the barriers for RL implementation is focused on developed countries. Among the most important emerging economies, Brazil, the largest Latin America economy, faces challenges such as a deficient logistics infrastructure and the recently enacted National Policy on solid waste. To bridge this gap, this paper identifies and evaluates the barriers for RL in the Brazilian context. An eleven-step research methodology is proposed. First, literature was thoroughly reviewed. fuzzy Delphi method (FDM) was used to obtain the critical list of barriers by experts and industrial managers’ opinions. Then, analytic hierarchy process (AHP) questionnaires were answered by electrical–electronic equipment (EEE) industry sector experts in order to obtain the priority ranking of barriers. This paper contributes with a compilation of the RL barriers from a systematic literature review process, a list of most common RL barriers accepted by Brazilian organizations, and a priority ranking of RL barriers for the electrical-electronic industry sector in Brazil. The “Economic related issues” category of barriers seems to be the first priority. The financial burden of tax and the uncertainty related to economic issues appear to be major obstacles for RL implementation.

Nanomaterials for biocatalyst immobilization – state of the art and future trends

Abstract: Nanotechnology is an area that has been growing over the years, being possible nowadays to find numerous materials constructed at nanoscale In addition, many applications have been attributed to these “new” materials In this review is presented a brief overview of nanoparticles used for the immobilization of enzymes Considering the extensive universe of immobilization in nanoparticles, some were chosen to be exposed here, such as chitosan, graphene, silica, polymers, magnetic, nanoflowers, among others Advantages, disadvantages and limitations of nanoimmobilization also be discussed Some applications of nanoimmobilized enzymes are presented, like as biodiesel, flavor synthesis ester and biosensors The purpose of this paper is to provide an overview of what is being studied in relation to nanoparticles for enzymes immobilization, and some discussions about them, aimed at assisting researchers in future studies and reviews

Carotenoids Functionality, Sources, and Processing by Supercritical Technology: A Review

Abstract: Carotenoid is a group of pigments naturally present in vegetal raw materials that have biological properties. These pigments have been used mainly in food, pharmaceutical, and cosmetic industries. Currently, the industrial production is executed through chemical synthesis, but natural alternatives of carotenoid production/attainment are in development. The carotenoid extraction occurs generally with vegetal oil and organic solvents, but supercritical technology is an alternative technique to the recovery of these compounds, presenting many advantages when compared to conventional process. Brazil has an ample diversity of vegetal sources inadequately investigated and, then, a major development of optimization and validation of carotenoid production/attainment methods is necessary, so that the benefits of these pigments can be delivered to the consumer.

Current developments in reversible solid oxide fuel cells

Abstract: Solid Oxide Fuel Cells (SOFC) and Solid Oxide Electrolyte Cells (SOEC) are often considered precluded mainly by their high cost, even when several technical issues have been continuously tackled over the past decades. Our energetic matrix is essentially based on finite fuel sources, which involve the emission of environmentally hazardous pollutants. Nevertheless, now there are several feasible and profitable benign routes for energy generation through solid oxide cells development, mainly for cells capable to produce energy and store it employing hydrogen as energy carrier. Those cells act reversibly as fuel or electrolyzer systems, which may be integrated in hybrid renewable energy plants and may be referred to as Reversible Solid Oxide Fuel Cells (RSOFC). In this article, the operation principles of SOEC and SOFC and the current state of the electrolyte, fuel and oxygen electrodes has been reviewed and discussed in detail. Each major section is divided into materials families, including manufacturing issues. Novel materials and processing techniques are currently in development and are summarized here. Moreover, key-points are suggested to overcome the known drawbacks and to improve the performance and economic feasibility in order to enhance the commercialization of RSOFC technology.

Sampling: how to select participants in my research study?

Abstract: Background: In this paper, the basic elements related to the selection of participants for a health research are discussed. Sample representativeness, sample frame, types of sampling, as well as the impact that non-respondents may have on results of a study are described. The whole discussion is supported by practical examples to facilitate the reader's understanding. Objective: To introduce readers to issues related to sampling.

Disturbance maintains alternative biome states.

Abstract: Understanding the mechanisms controlling the distribution of biomes remains a challenge. Although tropical biome distribution has traditionally been explained by climate and soil, contrasting vegetation types often occur as mosaics with sharp boundaries under very similar environmental conditions. While evidence suggests that these biomes are alternative states, empirical broad-scale support to this hypothesis is still lacking. Using community-level field data and a novel resource-niche overlap approach, we show that, for a wide range of environmental conditions, fire feedbacks maintain savannas and forests as alternative biome states in both the Neotropics and the Afrotropics. In addition, wooded grasslands and savannas occurred as alternative grassy states in the Afrotropics, depending on the relative importance of fire and herbivory feedbacks. These results are consistent with landscape scale evidence and suggest that disturbance is a general factor driving and maintaining alternative biome states and vegetation mosaics in the tropics.

Smartness that matters: towards a comprehensive and human-centred characterisation of smart cities

Abstract: The term ‘smart cities’ is a widely used, but at the same time a highly fuzzy concept. The fuzziness hinders our understanding on the benefits of its adoption, and explains the existence of many relevant activities with fragmented or distorted views of what a truly smart city is. The aim of this paper is to undertake a comprehensive review of how smart cities are perceived in the literature and in the light of the findings propose a clearer definition. Overview of the key terms, concepts and definitions associated to smart cities, reported in this paper, demonstrates that the definitions found in the academic literature have limited scope, and are overly focused on strategic drivers and specific actions, instead of making explicitly the connection between the concept of smart cities and the creation of environments that promote happiness and wellbeing of their residents—which should be the main function of a city. Following the thorough review on the smart cities literature, the paper proposes a comprehensive, human-centred, and context-free definition for smart cities. This definition brings an endogenous view on smart cities in which the central element is the direct participation of local actors and stakeholders in the process of thinking, defining, planning, and executing social, technological and urban transformations in cities.

Rosmarinic Acid--Pharmaceutical and Clinical Aspects.

Abstract: The biosynthesis and biotechnological production of Rosmarinic acid, a phenolic ester that is widespread in the plant kingdom, has been widely investigated. This compound has shown many remarkable biological and pharmacological activities, which have led to its pharmaceutical and analytical development, as well as clinical studies, which are summarized and analyzed here for the first time. This review compiles data from the Pubmed, Scopus, Scifinder, Web Of Science, and Science Direct databases published between 1990 and 2015, restricting the search to works with the keywords “Rosmarinic acid” in the title. The initial search identified more than 800 articles; after an initial screening and removal of duplicate works, the search was further refined, resulting in approximately 300 articles that were scrutinized and comprise this review. The articles were organized to describe extraction and isolation, analytical methods, pharmaceutical development, and biological and pharmacological activities [divided into nonclinical (in vitro, in vivo) and clinical studies], pharmacokinetic studies, and stability studies.

Depression as a Glial-Based Synaptic Dysfunction

Abstract: Recent studies combining pharmacological, behavioral, electrophysiological and molecular approaches indicate that depression results from maladaptive neuroplastic processes occurring in defined frontolimbic circuits responsible for emotional processing such as the prefrontal cortex, hippocampus, amygdala and ventral striatum. However, the exact mechanisms controlling synaptic plasticity that are disrupted to trigger depressive conditions have not been elucidated. Since glial cells (astrocytes and microglia) tightly and dynamically interact with synapses, engaging a bi-directional communication critical for the processing of synaptic information, we now revisit the role of glial cells in the etiology of depression focusing on a dysfunction of the "quad-partite" synapse. This interest is supported by the observations that depressive-like conditions are associated with a decreased density and hypofunction of astrocytes and with an increased microglia "activation" in frontolimbic regions, which is expected to contribute for the synaptic dysfunction present in depression. Furthermore, the traditional culprits of depression (glucocorticoids, biogenic amines, brain-derived neurotrophic factor, BDNF) affect glia functioning, whereas antidepressant treatments (serotonin-selective reuptake inhibitors, SSRIs, electroshocks, deep brain stimulation) recover glia functioning. In this context of a quad-partite synapse, systems modulating glia-synapse bidirectional communication-such as the purinergic neuromodulation system operated by adenosine 5'-triphosphate (ATP) and adenosine-emerge as promising candidates to "re-normalize" synaptic function by combining direct synaptic effects with an ability to also control astrocyte and microglia function. This proposed triple action of purines to control aberrant synaptic function illustrates the rationale to consider the interference with glia dysfunction as a mechanism of action driving the design of future pharmacological tools to manage depression.

ERICA: prevalences of hypertension and obesity in Brazilian adolescents

Abstract: OBJECTIVE To estimate the prevalence of arterial hypertension and obesity and the population attributable fraction of hypertension that is due to obesity in Brazilian adolescents. METHODS Data from participants in the Brazilian Study of Cardiovascular Risks in Adolescents (ERICA), which was the first national school-based, cross-section study performed in Brazil were evaluated. The sample was divided into 32 geographical strata and clusters from 32 schools and classes, with regional and national representation. Obesity was classified using the body mass index according to age and sex. Arterial hypertension was defined when the average systolic or diastolic blood pressure was greater than or equal to the 95th percentile of the reference curve. Prevalences and 95% confidence intervals (95%CI) of arterial hypertension and obesity, both on a national basis and in the macro-regions of Brazil, were estimated by sex and age group, as were the fractions of hypertension attributable to obesity in the population. RESULTS We evaluated 73,399 students, 55.4% female, with an average age of 14.7 years (SD = 1.6). The prevalence of hypertension was 9.6% (95%CI 9.0-10.3); with the lowest being in the North, 8.4% (95%CI 7.7-9.2) and Northeast regions, 8.4% (95%CI 7.6-9.2), and the highest being in the South, 12.5% (95%CI 11.0-14.2). The prevalence of obesity was 8.4% (95%CI 7.9-8.9), which was lower in the North region and higher in the South region. The prevalences of arterial hypertension and obesity were higher in males. Obese adolescents presented a higher prevalence of hypertension, 28.4% (95%CI 25.5-31.2), than overweight adolescents, 15.4% (95%CI 17.0-13.8), or eutrophic adolescents, 6.3% (95%CI 5.6-7.0). The fraction of hypertension attributable to obesity was 17.8%. CONCLUSIONS ERICA was the first nationally representative Brazilian study providing prevalence estimates of hypertension in adolescents. Regional and sex differences were observed. The study indicates that the control of obesity would lower the prevalence of hypertension among Brazilian adolescents by 1/5.

Regioselective, Solvent- and Metal-Free Chalcogenation of Imidazo[1,2-a]pyridines by Employing I2/DMSO as the Catalytic Oxidation System

Abstract: Highly efficient molecular-iodine-catalyzed chalcogenations (S and Se) of imidazo[1,2-a]pyridines were achieved by using diorganoyl dichalcogenides under solvent-free conditions. This approach afforded the desired products that had been chalcogenated regioselectively at the C3 position in up to 96 % yield by using DMSO as an oxidant, in the absence of a metal catalyst, and under an inert atmosphere. This mild, green approach allowed the preparation of different types of chalcogenated imidazo[1,2-a]pyridines with structural diversity. Furthermore, the current protocol was also extended to other N-heterocyclic cores.

Star formation along the Hubble sequence: Radial structure of the star formation of CALIFA galaxies

Abstract: Spanish Ministerio de Economia y Competitividad AYA2014-57490-P AYA2010-15081 Junta de Andalucia FQ1580 AYA2010-22111-C03-03 AYA2010-10904E AYA2013-42227P RyC-2011-09461 AYA2013-47742-C4-3-P EU SELGIFS exchange program FP7-PEOPLE-2013-IRSES-612701 CONACYT-125180 DGAPA-IA100815 Viabilidad, Diseno, Acceso y Mejora ICTS-2009-10 CAPES CNPq CNPq (Brazil) through Programa Ciencia sem Fronteiras 401452/2012-3 Marie Curie Career Integration Grant 303912

TRPA1 mediates trigeminal neuropathic pain in mice downstream of monocytes/macrophages and oxidative stress.

Abstract: Despite intense investigation, the mechanisms of the different forms of trigeminal neuropathic pain remain substantially unidentified. The transient receptor potential ankyrin 1 channel (encoded by TRPA1 ) has been reported to contribute to allodynia or hyperalgesia in some neuropathic pain models, including those produced by sciatic nerve constriction. However, the role of TRPA1 and the processes that cause trigeminal pain-like behaviours from nerve insult are poorly understood. The role of TRPA1, monocytes and macrophages, and oxidative stress in pain-like behaviour evoked by the constriction of the infraorbital nerve in mice were explored. C57BL/6 and wild-type ( Trpa1+/+ ) mice that underwent constriction of the infraorbital nerve exhibited prolonged (20 days) non-evoked nociceptive behaviour and mechanical, cold and chemical hypersensitivity in comparison to sham-operated mice ( P < 0.05– P < 0.001). Both genetic deletion of Trpa1 ( Trpa1−/− ) and pharmacological blockade (HC-030031 and A-967079) abrogated pain-like behaviours (both P < 0.001), which were abated by the antioxidant, α-lipoic acid, and the nicotinamide adenine dinucleotide phosphate oxidase inhibitor, apocynin (both P < 0.001). Nociception and hypersensitivity evoked by constriction of the infraorbital nerve was associated with intra- and perineural monocytic and macrophagic invasion and increased levels of oxidative stress by-products (hydrogen peroxide and 4-hydroxynonenal). Attenuation of monocyte/macrophage increase by systemic treatment with an antibody against the monocyte chemoattractant chemokine (C-C motif) ligand 2 (CCL2) or the macrophage-depleting agent, clodronate (both P < 0.05), was associated with reduced hydrogen peroxide and 4-hydroxynonenal perineural levels and pain-like behaviours (all P < 0.01), which were abated by perineural administration of HC-030031, α-lipoic acid or the anti-CCL2 antibody (all P < 0.001). The present findings propose that, in the constriction of the infraorbital nerve model of trigeminal neuropathic pain, pain-like behaviours are entirely mediated by the TRPA1 channel, targeted by increased oxidative stress by-products released from monocytes and macrophages clumping at the site of nerve injury. * Abbreviations : 4-HNE = : 4-hydroxynonenal AITC = : allyl isothiocyanate A-967079 = : (1 E ,3 E )-1-(4-Fluorophenyl)-2-methyl-1-penten-3-one oxime CION = : constriction of the infraorbital nerve HC-030031 = : (2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)- N -(4-isopropylphenyl) acetamide) LCL = : liposome-encapsulated clodronate

Remotely sensed resilience of tropical forests

Abstract: Remote sensing of tropical forest activity indicates that temporal autocorrelation—an indicator of slow recovery from stress—rises steeply as precipitation falls sufficiently. This offers some support for a tipping point for forest collapse.