Institution
University of Bergen
Education•Bergen, Hordaland, Norway•
About: University of Bergen is a education organization based out in Bergen, Hordaland, Norway. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 17106 authors who have published 52492 publications receiving 2009844 citations. The organization is also known as: Universitetet i Bergen & Universitas Bergensis.
Papers published on a yearly basis
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Bergen University College1, University of Bergen2, Sewanee: The University of the South3, COMSATS Institute of Information Technology4, University of Oslo5, GSI Helmholtz Centre for Heavy Ion Research6, Konkuk University7, Lawrence Livermore National Laboratory8, Czech Technical University in Prague9, Academy of Sciences of the Czech Republic10, Yale University11, Panjab University, Chandigarh12, Hungarian Academy of Sciences13, Variable Energy Cyclotron Centre14, Aligarh Muslim University15, Oak Ridge National Laboratory16
TL;DR: In this article, comprehensive results on π±, K±, k0 S, p(p) and ¯ Λ(Λ)¯ production at mid-rapidity (0 < yCMS < 0.5) in p-Pb collisions at √sNN = 5.02 TeV, measured by the ALICE detector at the LHC, are reported.
375 citations
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TL;DR: In this article, the authors measured ACE2 concentrations in 1485 men and 537 women with heart failure (index cohort) and found that the strongest predictor of elevated concentrations of ACE2 in both cohorts was male sex.
Abstract: AIMS: The current pandemic coronavirus SARS-CoV-2 infects a wide age group but predominantly elderly individuals, especially men and those with cardiovascular disease. Recent reports suggest an association with use of renin-angiotensin-aldosterone system (RAAS) inhibitors. Angiotensin-converting enzyme 2 (ACE2) is a functional receptor for coronaviruses. Higher ACE2 concentrations might lead to increased vulnerability to SARS-CoV-2 in patients on RAAS inhibitors. METHODS AND RESULTS: We measured ACE2 concentrations in 1485 men and 537 women with heart failure (index cohort). Results were validated in 1123 men and 575 women (validation cohort).The median age was 69 years for men and 75 years for women. The strongest predictor of elevated concentrations of ACE2 in both cohorts was male sex (estimate = 0.26, P < 0.001; and 0.19, P < 0.001, respectively). In the index cohort, use of ACE inhibitors, angiotensin receptor blockers (ARBs), or mineralocorticoid receptor antagonists (MRAs) was not an independent predictor of plasma ACE2. In the validation cohort, ACE inhibitor (estimate = -0.17, P = 0.002) and ARB use (estimate = -0.15, P = 0.03) were independent predictors of lower plasma ACE2, while use of an MRA (estimate = 0.11, P = 0.04) was an independent predictor of higher plasma ACE2 concentrations. CONCLUSION: In two independent cohorts of patients with heart failure, plasma concentrations of ACE2 were higher in men than in women, but use of neither an ACE inhibitor nor an ARB was associated with higher plasma ACE2 concentrations. These data might explain the higher incidence and fatality rate of COVID-19 in men, but do not support previous reports suggesting that ACE inhibitors or ARBs increase the vulnerability for COVID-19 through increased plasma ACE2 concentrations.
375 citations
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TL;DR: Flexible EEG criteria that employ the SCORE system to assemble a database for determining evidence‐based EEG criteria for NCSE are proposed.
Abstract: The diagnosis of nonconvulsive status epilepticus (NCSE) relies largely on electroencephalography (EEG) findings. The lack of a unified EEG terminology, and of evidence-based EEG criteria, leads to varying criteria for and ability to diagnose NCSE. We propose a unified terminology and classification system for NCSE, using, as a template, the Standardised Computer-based Organised Reporting of EEG (SCORE). This approach integrates the terminology recently proposed for the rhythmic and periodic patterns in critically ill patients, the electroclinical classification of NCSE (type of NCSE) and the context for the pathologic conditions and age-related epilepsy syndromes. We propose flexible EEG criteria that employ the SCORE system to assemble a database for determining evidence-based EEG criteria for NCSE.
374 citations
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TL;DR: Lienert et al. as mentioned in this paper used the HYPOCENTER system to locate earthquakes using data collected by small networks of seismometers, but it suffered from many of the same limitations as its predecessors (HYPO71, HYPOINVERSE, etc.).
Abstract: INTRODUCTION
Since the original version of HYPOCENTER was published (Lienert et al. , 1986), it has been used primarily to locate earthquakes using data collected by small networks of seismometers (e.g., Ambos et al. , 1985). In its original form it suffered from many of the same limitations as its predecessors (HYPO71, HYPOINVERSE, etc.). It could not use azimuth data, was unable to force the calculation of specific phases ( Pn, Pg , etc.) and was limited to locating events at station distances of less than about 500 km, due to a “flat earth” velocity model and coordinate system.
The increasing use of portable three-component seismometers has made it possible to determine the azimuth of a given event in addition to the arrival times of both primary and secondary phases. In principle, this allows single-station locations to be obtained, provided that the location software can use azimuth data. Global location capability is useful in...
374 citations
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TL;DR: It is concluded that adrenergic inputs to the paraventricular nucleus may influence cells that project to the median eminence and to preganglionic autonomic cell groups in the medulla and spinal cord.
Abstract: The distribution of catecholaminergic fibers and cell bodies in the paraventricular and supraoptic nuclei of the hypothalamus was investigated with immunohistochemical methods in the adult albino rat. Sections through the nuclei were stained with antisera to the catecholamine synthesizing enzymes tyrosine hydroxylase (TH), dopamine-beta-hydroxylase (DBH), and phenylethanolamine-N-methyltransferase (PNMT). The results suggest that adrenergic (PNMT-stained) fibers innervate the entire parvocellular division of the paraventricular nucleus, although the highest density of fibers was found in the medial part of the division. Only widely scattered adrenergic fibers are found in the magnocellular division of the nucleus and in the supraoptic nucleus. Noradrenergic fibers appear to innervate the periventricular zone of the paraventricular nucleus and those parts of the paraventricular and supraoptic nuclei that contain predominantly vasopressinergic neurons in both the normal and in the homozygous Brattleboro rat. Significant numbers--somewhat more than 500--of dopaminergic (TH-stained) neurons are found in the paraventricular nucleus; the cells are distributed throughout the nucleus but are concentrated in the medial and periventricular parts of the parvocellular division. Double-labeling experiments with the retrogradely transported tracer true blue indicate that between 4% and 8% of the dopaminergic neurons in the paraventricular nucleus project to the region of the dorsal vagal complex and/or thoracic levels of the spinal cord. It is concluded that adrenergic inputs to the paraventricular nucleus may influence cells that project to the median eminence and to preganglionic autonomic cell groups in the medulla and spinal cord. Noradrenergic inputs to the supraoptic and paraventricular nuclei may influence primarily vasopressinergic cells that project to the posterior lobe of the pituitary, as well as cells in the periventricular part of the paraventricular nucleus that project to the median eminence.
374 citations
Authors
Showing all 17370 results
Name | H-index | Papers | Citations |
---|---|---|---|
Stephen V. Faraone | 188 | 1427 | 140298 |
Patrick O. Brown | 183 | 755 | 200985 |
Anil K. Jain | 183 | 1016 | 192151 |
Marc Weber | 167 | 2716 | 153502 |
Johan Auwerx | 158 | 653 | 95779 |
Leif Groop | 158 | 919 | 136056 |
Charles M. Perou | 156 | 573 | 202951 |
Bart Staels | 152 | 824 | 86638 |
Zhenwei Yang | 150 | 956 | 109344 |
G. Eigen | 148 | 2188 | 117450 |
Thomas Lohse | 148 | 1237 | 101631 |
Marco Costa | 146 | 1458 | 105096 |
Timothy P. Hughes | 145 | 831 | 91357 |
Hermann Kolanoski | 145 | 1279 | 96152 |
Kjell Fuxe | 142 | 1479 | 89846 |