Institution
University of California, Santa Barbara
Education•Santa Barbara, California, United States•
About: University of California, Santa Barbara is a education organization based out in Santa Barbara, California, United States. It is known for research contribution in the topics: Population & Laser. The organization has 30281 authors who have published 80852 publications receiving 4626827 citations. The organization is also known as: UC Santa Barbara & UCSB.
Topics: Population, Laser, Galaxy, Context (language use), Quantum well
Papers published on a yearly basis
Papers
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TL;DR: Defaunation is both a pervasive component of the planet’s sixth mass extinction and also a major driver of global ecological change.
Abstract: We live amid a global wave of anthropogenically driven biodiversity loss: species and population extirpations and, critically, declines in local species abundance. Particularly, human impacts on animal biodiversity are an under-recognized form of global environmental change. Among terrestrial vertebrates, 322 species have become extinct since 1500, and populations of the remaining species show 25% average decline in abundance. Invertebrate patterns are equally dire: 67% of monitored populations show 45% mean abundance decline. Such animal declines will cascade onto ecosystem functioning and human well-being. Much remains unknown about this “Anthropocene defaunation”; these knowledge gaps hinder our capacity to predict and limit defaunation impacts. Clearly, however, defaunation is both a pervasive component of the planet’s sixth mass extinction and also a major driver of global ecological change.
2,697 citations
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TL;DR: This chapter addresses the psychological effects of social stigma by reviewing and organizing recent theory and empirical research within an identity threat model of stigma, which posits that situational cues, collective representations of one's stigma status, and personal beliefs and motives shape appraisals of the significance of stigma-relevant situations for well-being.
Abstract: This chapter addresses the psychological effects of social stigma. Stigma directly affects the stigmatized via mechanisms of discrimination, expectancy confirmation, and automatic stereotype activation, and indirectly via threats to personal and social identity. We review and organize recent theory and empirical research within an identity threat model of stigma. This model posits that situational cues, collective representations of one's stigma status, and personal beliefs and motives shape appraisals of the significance of stigma-relevant situations for well-being. Identity threat results when stigma-relevant stressors are appraised as potentially harmful to one's social identity and as exceeding one's coping resources. Identity threat creates involuntary stress responses and motivates attempts at threat reduction through coping strategies. Stress responses and coping efforts affect important outcomes such as self-esteem, academic achievement, and health. Identity threat perspectives help to explain the...
2,680 citations
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TL;DR: In this article, the grain-size dependence of parameters with coercive force as high as 2,000 Oe in x = 0.6 titanomagnetite was found.
2,657 citations
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TL;DR: It is shown that a bounded, isolated quantum system of many particles in a specific initial state will approach thermal equilibrium if the energy eigenfunctions which are superposed to form that state obey Berry's conjecture, and argued that these results constitute a sound foundation for quantum statistical mechanics.
Abstract: We show that a bounded, isolated quantum system of many particles in a specific initial state will approach thermal equilibrium if the energy eigenfunctions which are superposed to form that state obey Berry's conjecture. Berry's conjecture is expected to hold only if the corresponding classical system is chaotic, and essentially states that the energy eigenfunctions behave as if they were Gaussian random variables. We review the existing evidence, and show that previously neglected effects substantially strengthen the case for Berry's conjecture. We study a rarefied hard-sphere gas as an explicit example of a many-body system which is known to be classically chaotic, and show that an energy eigenstate which obeys Berry's conjecture predicts a Maxwell-Boltzmann, Bose-Einstein, or Fermi-Dirac distribution for the momentum of each constituent particle, depending on whether the wave functions are taken to be nonsymmetric, completely symmetric, or completely antisymmetric functions of the positions of the particles. We call this phenomenon eigenstate thermalization. We show that a generic initial state will approach thermal equilibrium at least as fast as O(\ensuremath{\Elzxh}/\ensuremath{\Delta})${\mathit{t}}^{\mathrm{\ensuremath{-}}1}$, where \ensuremath{\Delta} is the uncertainty in the total energy of the gas. This result holds for an individual initial state; in contrast to the classical theory, no averaging over an ensemble of initial states is needed. We argue that these results constitute a sound foundation for quantum statistical mechanics.
2,649 citations
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TL;DR: Tremendous progress has been made in understanding the molecular basis of the antiviral actions of interferons (IFNs), as well as strategies evolved by viruses to antagonize the actions of IFNs.
Abstract: Tremendous progress has been made in understanding the molecular basis of the antiviral actions of interferons (IFNs), as well as strategies evolved by viruses to antagonize the actions of IFNs. Furthermore, advances made while elucidating the IFN system have contributed significantly to our understanding in multiple areas of virology and molecular cell biology, ranging from pathways of signal transduction to the biochemical mechanisms of transcriptional and translational control to the molecular basis of viral pathogenesis. IFNs are approved therapeutics and have moved from the basic research laboratory to the clinic. Among the IFN-induced proteins important in the antiviral actions of IFNs are the RNA-dependent protein kinase (PKR), the 2',5'-oligoadenylate synthetase (OAS) and RNase L, and the Mx protein GTPases. Double-stranded RNA plays a central role in modulating protein phosphorylation and RNA degradation catalyzed by the IFN-inducible PKR kinase and the 2'-5'-oligoadenylate-dependent RNase L, respectively, and also in RNA editing by the IFN-inducible RNA-specific adenosine deaminase (ADAR1). IFN also induces a form of inducible nitric oxide synthase (iNOS2) and the major histocompatibility complex class I and II proteins, all of which play important roles in immune response to infections. Several additional genes whose expression profiles are altered in response to IFN treatment and virus infection have been identified by microarray analyses. The availability of cDNA and genomic clones for many of the components of the IFN system, including IFN-alpha, IFN-beta, and IFN-gamma, their receptors, Jak and Stat and IRF signal transduction components, and proteins such as PKR, 2',5'-OAS, Mx, and ADAR, whose expression is regulated by IFNs, has permitted the generation of mutant proteins, cells that overexpress different forms of the proteins, and animals in which their expression has been disrupted by targeted gene disruption. The use of these IFN system reagents, both in cell culture and in whole animals, continues to provide important contributions to our understanding of the virus-host interaction and cellular antiviral response.
2,621 citations
Authors
Showing all 30652 results
Name | H-index | Papers | Citations |
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George M. Whitesides | 240 | 1739 | 269833 |
Yi Chen | 217 | 4342 | 293080 |
Simon D. M. White | 189 | 795 | 231645 |
George Efstathiou | 187 | 637 | 156228 |
Peidong Yang | 183 | 562 | 144351 |
David R. Williams | 178 | 2034 | 138789 |
Alan J. Heeger | 171 | 913 | 147492 |
Richard H. Friend | 169 | 1182 | 140032 |
Jiawei Han | 168 | 1233 | 143427 |
Gang Chen | 167 | 3372 | 149819 |
Alexander S. Szalay | 166 | 936 | 145745 |
Omar M. Yaghi | 165 | 459 | 163918 |
Carlos S. Frenk | 165 | 799 | 140345 |
Yang Yang | 164 | 2704 | 144071 |
Carlos Bustamante | 161 | 770 | 106053 |