University of Cyprus

About: University of Cyprus is a education organization based out in Nicosia, Cyprus. It is known for research contribution in the topics: Large Hadron Collider & Context (language use). The organization has 3624 authors who have published 15157 publications receiving 412135 citations.

Neurodegeneration and Inflammation-An Interesting Interplay in Parkinson's Disease.

Abstract: Parkinson’s disease (PD) is a neurodegenerative disorder, caused by, so far, unknown pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated mechanisms are pivotal to the pathogenicity and progression of the disease. In this review, we highlight the binary role of microglia activation in the pathophysiology of the disorder, both neuroprotective and neuromodulatory. We present how the expression of several cytokines implicated in dopaminergic neurons (DA) degeneration could be used as biomarkers for PD. Viral infections have been studied and correlated to the disease progression, usually operating as trigger factors for the inflammatory process. The gut–brain axis and the possible contribution of the peripheral bowel inflammation to neuronal death, mainly dopaminergic neurons, seems to be a main contributor of brain neuroinflammation. The role of the immune system has also been analyzed implicating a-synuclein in the activation of innate and adaptive immunity. We also discuss therapeutic approaches concerning PD and neuroinflammation, which have been studied in experimental and in vitro models and data stemming from epidemiological studies.

Search for narrow resonances in dilepton mass spectra in pp collisions at s=7TeV

Abstract: A search for narrow, high-mass resonances decaying to electron or muon pairs has been performed using pp collision data collected at sqrt(s)=7 TeV by the CMS experiment in 2011. The data sample corresponds to an integrated luminosity of approximately 5 inverse femtobarns. The event yields observed in the signal regions are consistent with predictions of the standard model backgrounds, and upper limits on the cross section times branching fraction for a resonance decaying to dileptons are extracted from a shape analysis of the dilepton invariant mass distribution. The resulting mass limits at 95% confidence level are 2330 GeV for the Z' in the Sequential Standard Model, 2000 GeV for the superstring-inspired Z'(psi) resonance, 890 (540) GeV for the Stueckelberg extension Z'(St) with the mass parameter epsilon=0.06 (0.04), and 2140 (1810) GeV for Kaluza--Klein gravitons with the coupling parameter k/Mbar(Pl) of 0.10 (0.05). These limits are the most stringent to date.

The gender imbalance in participation in Canadian universities (1977-2005)

Abstract: More females than males have been attending Canadian universities over the past decade and this gender imbalance in university participation has been increasing. We use the Linear Probability and Logit models to investigate the determinants of attending university and explore the reasons for the increasing gender imbalance. We find that, in gender-specific equations, the values of the coefficients attached to variables and the values of the variables themselves are both important in explaining the rising level of the university participation rate for women and men. The important variables include a time trend to capture the evolving societal norms, the dynamic influence of parental education, the earnings premium for a university degree, tuition fees and real income. The increasing gap between the female and male participation rates (15 percentage points by 2005) can be accounted for equally by differences in the coefficients in female and male participation equations and the widening gap in the university premium for women and men.