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Institution

University of Maine

EducationOrono, Maine, United States
About: University of Maine is a education organization based out in Orono, Maine, United States. It is known for research contribution in the topics: Population & Ice sheet. The organization has 8637 authors who have published 16932 publications receiving 590124 citations. The organization is also known as: University of Maine at Orono.


Papers
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Journal ArticleDOI
TL;DR: A role for calpains in both the degenerative and regenerative aspects of mdx dystrophy is supported, with findings show that total calpain concentration is elevated in both 4-week and 14-week mdx mice.

215 citations

Journal ArticleDOI
TL;DR: Its very high sorption capacity and relatively low production cost make chitosan an attractive sorbent for the removal of heavy metals from waste streams.

215 citations

Journal ArticleDOI
TL;DR: This study demonstrates that ultrahigh resolution mass spectrometry and multivariate methods can be used to identify marker components to gain a molecular-scale description and understanding of C dynamics.
Abstract: The chemical properties of organic matter affect important soil processes such as speciation, solubilization, and transport of plant nutrients and metals. This work uses ultrahigh resolution electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry to determine the molecular composition of three organic matter fractions of soils and aqueous extracts of crop biomass. Comparison of the van Krevelen plots allowed tracking the changes in organic matter with increasing humification. Aqueous plant biomass extracts contain a diverse mixture of lipids, proteins, and lignins. Soil aqueous extracts were marked by increases in lignin and carbohydrate components and decrease in the protein component as compared to the plant extract. Refractory humic acid fractions were marked by decrease in the lignin component and increases in the lipid and condensed aromatic components. The multivariate indicator species analysis was used to identify marker components of the four organic matter types inves...

214 citations

Journal ArticleDOI
TL;DR: Consuming a WB drink for 6 weeks significantly reduced the levels of oxidized DNA bases and increased the resistance to oxidatively induced DNA damage, and no significant differences were detected for markers of endothelial function and the other variables under study.
Abstract: Wild blueberries (WB) (Vaccinium angustifolium) are rich sources of polyphenols, such as flavonols, phenolic acids and anthocyanins (ACNs), reported to decrease the risk of cardiovascular and degenerative diseases. This study investigated the effect of regular consumption of a WB or a placebo (PL) drink on markers of oxidative stress, inflammation and endothelial function in subjects with risk factors for cardiovascular disease. Eighteen male volunteers (ages 47.8 ± 9.7 years; body mass index 24.8 ± 2.6 kg/m2) received according to a cross-over design, a WB (25 g freeze-dried powder, providing 375 mg of ACNs) or a PL drink for 6 weeks, spaced by a 6-week wash-out. Endogenous and oxidatively induced DNA damage in blood mononuclear cells, serum interleukin levels, reactive hyperemia index, nitric oxide, soluble vascular adhesion molecule concentration and other variables were analyzed. Wild blueberry drink intake significantly reduced the levels of endogenously oxidized DNA bases (from 12.5 ± 5.6 % to 9.6 ± 3.5 %, p ≤ 0.01) and the levels of H2O2-induced DNA damage (from 45.8 ± 7.9 % to 37.2 ± 9.1 %, p ≤ 0.01), while no effect was found after the PL drink. No significant differences were detected for markers of endothelial function and the other variables under study. In conclusion, the consumption of the WB drink for 6 weeks significantly reduced the levels of oxidized DNA bases and increased the resistance to oxidatively induced DNA damage. Future studies should address in greater detail the role of WB in endothelial function. This study was registered at www.isrctn.org as ISRCTN47732406.

214 citations


Authors

Showing all 8729 results

NameH-indexPapersCitations
Clifford J. Rosen11165547881
Juan S. Bonifacino10830346554
John D. Aber10720448500
Surendra P. Shah9971032832
Charles T. Driscoll9755437355
Samuel Madden9538846424
Lihua Xiao9349532721
Patrick G. Hatcher9140127519
Pedro J. J. Alvarez8937834837
George R. Pettit8984831759
James R. Wilson89127137470
Steven Girvin8636638963
Peter Marler8117422070
Garry R. Buettner8030429273
Paul Andrew Mayewski8042029356
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202332
2022134
2021834
2020756
2019738
2018725