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Showing papers in "New Journal of Physics in 2013"


Journal ArticleDOI
TL;DR: In this article, a deep multi-task artificial neural network is used to predict multiple electronic ground and excited-state properties, such as atomization energy, polarizability, frontier orbital eigenvalues, ionization potential, electron affinity and excitation energies.
Abstract: The combination of modern scientific computing with electronic structure theory can lead to an unprecedented amount of data amenable to intelligent data analysis for the identification of meaningful, novel and predictive structure?property relationships. Such relationships enable high-throughput screening for relevant properties in an exponentially growing pool of virtual compounds that are synthetically accessible. Here, we present a machine learning model, trained on a database of ab initio calculation results for thousands of organic molecules, that simultaneously predicts multiple electronic ground- and excited-state properties. The properties include atomization energy, polarizability, frontier orbital eigenvalues, ionization potential, electron affinity and excitation energies. The machine learning model is based on a deep multi-task artificial neural network, exploiting the underlying correlations between various molecular properties. The input is identical to ab initio methods, i.e.?nuclear charges and Cartesian coordinates of all atoms. For small organic molecules, the accuracy of such a ?quantum machine? is similar, and sometimes superior, to modern quantum-chemical methods?at negligible computational cost.

488 citations


Journal ArticleDOI
TL;DR: In this article, the ionization dynamics of single nitrogen-vacancy center (NV) in bulk diamond at room temperature during illumination and its dependence on the excitation wavelength and power were investigated.
Abstract: The nitrogen–vacancy centre (NV) has drawn much attention for over a decade, yet detailed knowledge of the photophysics needs to be established. Under typical conditions, the NV can have two stable charge states, negative (NV−) or neutral (NV0), with photo-induced interconversion of these two states. Here, we present detailed studies of the ionization dynamics of single NV centres in bulk diamond at room temperature during illumination and its dependence on the excitation wavelength and power. We apply a recent method which allows us to directly measure the charge state of a single NV centre, and observe its temporal evolution. We find that the steady-state NV− population is always ⩽75% for 450–610 nm excitation wavelength. In combination with saturation measurements, we show that the optimal excitation wavelength is around 510–540 nm. Furthermore, the relative absorption cross-section of NV− is determined for 540–610 nm, revealing a double-peak structure. Finally, the energy of the NV− ground state of 2.6 eV below the conduction band is measured. These results reveal new insights into the charge state dynamics of the NV centre.

335 citations


Journal ArticleDOI
TL;DR: The dual symmetry between electric and magnetic fields is an important intrinsic property of Maxwell equations in free space as mentioned in this paper, which underlies the conservation of optical helicity and is closely related to the separation of spin and orbital degrees of freedom of light.
Abstract: The dual symmetry between electric and magnetic fields is an important intrinsic property of Maxwell equations in free space. This symmetry underlies the conservation of optical helicity and, as we show here, is closely related to the separation of spin and orbital degrees of freedom of light (the helicity flux coincides with the spin angular momentum). However, in the standard field-theory formulation of electromagnetism, the field Lagrangian is not dual symmetric. This leads to problematic dual-asymmetric forms of the canonical energy–momentum, spin and orbital angular-momentum tensors. Moreover, we show that the components of these tensors conflict with the helicity and energy conservation laws. To resolve this discrepancy between the symmetries of the Lagrangian and Maxwell equations, we put forward a dual-symmetric Lagrangian formulation of classical electromagnetism. This dual electromagnetism preserves the form of Maxwell equations, yields meaningful canonical energy–momentum and angular-momentum tensors, and ensures a self-consistent separation of the spin and orbital degrees of freedom. This provides a rigorous derivation of the results suggested in other recent approaches. We make the Noether analysis of the dual symmetry and all the Poincare symmetries, examine both local and integral conserved quantities and show that only the dual electromagnetism naturally produces a complete self-consistent set of conservation laws. We also discuss the observability of physical quantities distinguishing the standard and dual theories, as well as relations to quantum weak measurements and various optical experiments.

329 citations


Journal ArticleDOI
Jie Zhao1, Qiang Cheng, Chen Jie1, Mei Qing Qi1, Wei Xiang Jiang1, Tie Jun Cui 
TL;DR: In this article, a polarization-insensitive tunable tunable metamaterial absorber with varactor diodes embedded between metammaterial units is presented. But the design, analysis and measurements of the tunability of the absorber are not discussed.
Abstract: We present the design, analysis and measurements of a polarization-insensitive tunable metamaterial absorber with varactor diodes embedded between metamaterial units. The basic unit shows excellent absorptivity in the designed frequency band over a wide range of incident angles. By regulating the reverse bias voltage on the varactor diode, the absorption frequency of the designed unit can be controlled continuously. The absorption mechanism is interpreted using the electromagnetic-wave interference theory. When the metamaterial units are placed along two orthogonal directions, the absorber is insensitive to the polarization of incident waves. The tunability of the absorber has been verified by experimental results with the measured bandwidth of 1.5?GHz (or relative bandwidth of 30%).

290 citations


Journal ArticleDOI
TL;DR: In this paper, a small-scale quantum information processor based on a string of 40Ca+ ions confined in a macroscopic linear Paul trap is presented, which includes non-coherent operations allowing us to realize arbitrary Markovian processes.
Abstract: Quantum computers hold the promise to solve certain problems exponentially faster than their classical counterparts. Trapped atomic ions are among the physical systems in which building such a computing device seems viable. In this work we present a small-scale quantum information processor based on a string of 40Ca+ ions confined in a macroscopic linear Paul trap. We review our set of operations which includes non-coherent operations allowing us to realize arbitrary Markovian processes. In order to build a larger quantum information processor it is mandatory to reduce the error rate of the available operations which is only possible if the physics of the noise processes is well understood. We identify the dominant noise sources in our system and discuss their effects on different algorithms. Finally we demonstrate how our entire set of operations can be used to facilitate the implementation of algorithms by examples of the quantum Fourier transform and the quantum order finding algorithm.

283 citations


Journal ArticleDOI
TL;DR: A beamline for the X-ray free electron laser (XFEL) of SPring-8 Angstrom Compact free electron LAser (SACLA) provides hard x-ray pulses in the range 4.5-19.5 keV as mentioned in this paper.
Abstract: A beamline for the x-ray free electron laser (XFEL) of SPring-8 Angstrom Compact free electron LAser (SACLA) provides hard x-ray pulses in the range 4.5–19.5 keV. Its optical system in an optics hutch delivers a pink beam below 15 keV with either of two double-mirror systems or a monochromatic beam with a double-crystal monochromator. These XFEL beams are used for various types of measurement at experimental stations, e.g. x-ray diffraction, coherent diffraction imaging, x-ray spectroscopy and pump-and-probe measurement. The experimental stations consist of experimental hutches and control stations, and a femtosecond optical laser which is synchronized with XFEL pulses. Photon diagnostics have been performed for measuring radiation parameters in a shot-by-shot manner.

237 citations


Journal ArticleDOI
TL;DR: In this article, the authors demonstrate the non-ergodicity of a simple Markovian stochastic process with space-dependent diffusion coefficient D(x), which yields anomalous diffusion of the form hx 2 (t)i't 2/(2 ).
Abstract: We demonstrate the non-ergodicity of a simple Markovian stochastic process with space-dependent diffusion coefficient D(x). For power-law forms D(x) ' |x| , this process yields anomalous diffusion of the form hx 2 (t)i ' t 2/(2 ) . Interestingly, in both the sub- and superdiffusive regimes we observe weak ergodicity breaking: the scaling of the time-averaged mean-squared displacement 2 (1) remains linear in the lag time 1 and thus differs from the corresponding ensemble average hx 2 (t)i. We analyse the non-ergodic behaviour of this process in terms of the time-averaged mean-squared displacement 2 and its random features, i.e. the statistical distribution of 2 and the ergodicity breaking parameters. The heterogeneous diffusion model represents an alternative approach to non-ergodic, anomalous diffusion that might be particularly relevant for diffusion in heterogeneous media.

223 citations


Journal ArticleDOI
TL;DR: In this article, the authors developed a thorough numerical simulation using realistic simulated orbits and incorporating the effects of pointing error, diffraction, atmosphere and telescope design, to obtain estimates of the loss and background noise which a satellite-based system would experience.
Abstract: Optical quantum communication utilizing satellite platforms has the potential to extend the reach of quantum key distribution (QKD) from terrestrial limits of ?200?km to global scales. We have developed a thorough numerical simulation using realistic simulated orbits and incorporating the effects of pointing error, diffraction, atmosphere and telescope design, to obtain estimates of the loss and background noise which a satellite-based system would experience. Combining with quantum optics simulations of sources and detection, we determine the length of secure key for QKD, as well as entanglement visibility and achievable distances for fundamental experiments. We analyse the performance of a low Earth orbit satellite for downlink and uplink scenarios of the quantum optical signals. We argue that the advantages of locating the quantum source on the ground justify a greater scientific interest in an uplink as compared to a downlink. An uplink with a ground transmitter of at least 25?cm diameter and a 30?cm receiver telescope on the satellite could be used to successfully perform QKD multiple times per week with either an entangled photon source or with a weak coherent pulse source, as well as perform long-distance Bell tests and quantum teleportation. Our model helps to resolve important design considerations such as operating wavelength, type and specifications of sources and detectors, telescope designs, specific orbits and ground station locations, in view of anticipated overall system performance.

216 citations


Journal ArticleDOI
TL;DR: In this article, a power-law relaxation over several decades in time to the thermal plateau value under the confinement of the harmonic tweezer potential was shown. But the authors did not consider the effect of the size of the tracer beads.
Abstract: We report the results of single tracer particle tracking by optical tweezers and video microscopy in micellar solutions. From careful analysis in terms of different stochastic models, we show that the polystyrene tracer beads of size 0.52-2.5µm after short-time normal diffusion turn over to perform anomalous diffusion of the form hr 2 (t)i ' t with 0.3. This free anomalous diffusion is ergodic and consistent with a description in terms of the generalized Langevin equation with a power-law memory kernel. With optical tweezers tracking, we unveil a power-law relaxation over several decades in time to the thermal plateau value under the confinement of the harmonic tweezer potential, as predicted previously (Phys. Rev. E 85 021147 (2012)). After the subdiffusive motion in the millisecond range, the motion becomes faster and turns either back to normal Brownian diffusion or to even faster superdiffusion, depending on the size of the tracer beads.

213 citations


Journal ArticleDOI
TL;DR: In this article, the concept of topological order has been explored in the context of dissipative dynamics for fermionic systems, where the spectrum and the state of the system are not as tightly related as in the Hamiltonian context.
Abstract: Topological states of fermionic matter can be induced by means of a suitably engineered dissipative dynamics. Dissipation then does not occur as a perturbation, but rather as the main resource for many-body dynamics, providing a targeted cooling into topological phases starting from arbitrary initial states. We explore the concept of topological order in this setting, developing and applying a general theoretical framework based on the system density matrix that replaces the wave function appropriate for the discussion of Hamiltonian ground-state physics. We identify key analogies and differences to the more conventional Hamiltonian scenario. Differences essentially arise from the fact that the properties of the spectrum and of the state of the system are not as tightly related as in the Hamiltonian context. We provide a symmetry-based topological classification of bulk steady states and identify the classes that are achievable by means of quasi-local dissipative processes driving into superfluid paired states. We also explore the fate of the bulk-edge correspondence in the dissipative setting and demonstrate the emergence of Majorana edge modes. We illustrate ourfindings in one- and two-dimensional models that are experimentally realistic in the context of cold atoms.

211 citations


Journal ArticleDOI
TL;DR: In this paper, an improved theory for the renormalization in narrow gap semiconductors is proposed, which is fit using an n 1/3 scaling law which reflects an electron-electron exchange interaction.
Abstract: Optical absorption edge measurements are performed on I doped PbTe using diffuse reflectance infrared Fourier transform spectroscopy. The Burstein-Moss shift, an increase in the absorption edge (optical band gap) with increasing doping level, is explored. The optical gap increases on the order of 0.1eV for doping levels ranging from 3◊10 18 to 2◊10 20 cm 3 , relevant doping levels for good thermoelectric materials. Chemical potential is estimated from transport measurements—specifically, Hall effect and Seebeck coefficient—using a single band Kane model. In heavily doped semiconductors, it is well-known that the band gap shrinks with increasing doping level. This effect, known as band gap renormalization, is fit here using an n 1/3 scaling law which reflects an electron-electron exchange interaction. The renormalization effect in these samples is shown to be more than 0.1eV, on the same order of magnitude as the band gap itself. Existing models do not explain such large relative changes in band gap and are not entirely self-consistent. An improved theory for the renormalization in narrow gap semiconductors is required.

Journal ArticleDOI
TL;DR: In this paper, it was shown that the asymmetry properties of a pure state relative to the symmetry group G are completely specified by the characteristic function of the state, defined as χψ(g) ≡ 〈ψ|U(g)|ψ〉 where g∈G and U is the unitary representation of interest.
Abstract: If a system undergoes symmetric dynamics, then the final state of the system can only break the symmetry in ways in which it was broken by the initial state, and its measure of asymmetry can be no greater than that of the initial state. It follows that for the purpose of understanding the consequences of symmetries of dynamics, in particular, complicated and open-system dynamics, it is useful to introduce the notion of a state's asymmetry properties, which includes the type and measure of its asymmetry. We demonstrate and exploit the fact that the asymmetry properties of a state can also be understood in terms of information-theoretic concepts, for instance in terms of the state's ability to encode information about an element of the symmetry group. We show that the asymmetry properties of a pure state ψ relative to the symmetry group G are completely specified by the characteristic function of the state, defined as χψ(g) ≡ 〈ψ|U(g)|ψ〉 where g∈G and U is the unitary representation of interest. For a symmetry described by a compact Lie group G, we show that two pure states can be reversibly interconverted one to the other by symmetric operations if and only if their characteristic functions are equal up to a one-dimensional representation of the group. Characteristic functions also allow us to easily identify the conditions for one pure state to be converted to another by symmetric operations (in general irreversibly) for the various paradigms of single-copy transformations: deterministic, state-to-ensemble, stochastic and catalyzed.

Journal ArticleDOI
TL;DR: In this paper, the authors investigated the temperature-dependent fine structure of the zero-phonon line (ZPL) of the SiV centres in chemical vapour deposition (CVD) nanodiamonds on iridium and an ensemble of SiV centers in a high-quality, low-stress CVD diamond film.
Abstract: We study single silicon vacancy (SiV) centres in chemical vapour deposition (CVD) nanodiamonds on iridium as well as an ensemble of SiV centres in a high-quality, low-stress CVD diamond film by using temperature-dependent luminescence spectroscopy in the temperature range 5?295?K. We investigate in detail the temperature-dependent fine structure of the zero-phonon line (ZPL) of the SiV centres. The ZPL transition is affected by inhomogeneous as well as temperature-dependent homogeneous broadening and blue shifts by about 20?cm?1 upon cooling from room temperature to 5?K. We employ excitation power-dependent g(2) measurements to explore the temperature-dependent internal population dynamics of single SiV centres and infer mostly temperature-independent dynamics.

Journal ArticleDOI
TL;DR: In this article, a one-atom-thick mantle cloak is realized by means of a patterned metasurface comprised of a periodic array of graphene patches, whose surface impedance can be modeled with a simple yet accurate analytical expression.
Abstract: We propose and analyze a graphene-based cloaking metasurface aimed at achieving widely tunable scattering cancelation in the terahertz (THz) spectrum. This ‘one-atom-thick’ mantle cloak is realized by means of a patterned metasurface comprised of a periodic array of graphene patches, whose surface impedance can be modeled with a simple yet accurate analytical expression. By adjusting the geometry and Fermi energy of graphene nanopatches, the metasurface reactance may be tuned from inductive to capacitive, as a function of the relative kinetic inductance and the geometric patch capacitance, enabling the possibility of effectively cloaking both dielectric and conducting objects at THz frequencies with the same metasurface. We envision applications for low-observable nanostructures and efficient THz sensing, routing and detection.

Journal ArticleDOI
Georges Aad1, Alexander Kupco2, Paolo Laurelli, Stephen Sekula3  +2959 moreInstitutions (200)
TL;DR: In this paper, the production of W bosons in association with two jets in proton-proton collisions at a center-of-mass energy of root s = 7 TeV has been analyzed for the presence of double-parton interactions using data corresponding to an integrated luminosity of 36 pb(-1), collected with the ATLAS detector at the Large Hadron Collider.
Abstract: The production of W bosons in association with two jets in proton-proton collisions at a centre-of-mass energy of root s = 7 TeV has been analysed for the presence of double-parton interactions using data corresponding to an integrated luminosity of 36 pb(-1), collected with the ATLAS detector at the Large Hadron Collider. The fraction of events arising from double-parton interactions, f(DP)((D)), has been measured through the p(T) balance between the two jets and amounts to f(DP)((D)) = 0.08 +/- 0.01 (stat.) +/- 0.02 (sys.) for jets with transverse momentum p(T) > 20 GeV and rapidity vertical bar y vertical bar < 2.8. This corresponds to a measurement of the effective area parameter for hard double-parton interactions of sigma(eff) = 15 +/- 3 (stat.)(-3)(+5) (sys.) mb.

Journal ArticleDOI
TL;DR: In this paper, the authors demonstrate the full realization of Feynman's famous thought experiment by placing a movable mask in front of a double-slit to control the transmission through the individual slits.
Abstract: Double-slit diffraction is a corner stone of quantum mechanics. It illustrates key features of quantum mechanics: interference and the particle-wave duality of matter. In 1965, Richard Feynman presented a thought experiment to show these features. Here we demonstrate the full realization of his famous thought experiment. By placing a movable mask in front of a double-slit to control the transmission through the individual slits, probability distributions for single- and double-slit arrangements were observed. Also, by recording single electron detection events diffracting through a double-slit, a diffraction pattern was built up from individual events.

Journal ArticleDOI
TL;DR: In this article, a class of multiqubit quantum states which generalize graph states was introduced, which correspond to an underlying mathematical hypergraph, i.e. a graph where edges connecting more than two vertices are considered.
Abstract: We introduce a class of multiqubit quantum states which generalizes graph states. These states correspond to an underlying mathematical hypergraph, i.e. a graph where edges connecting more than two vertices are considered. We derive a generalized stabilizer formalism to describe this class of states. We introduce the notion of k-uniformity and show that this gives rise to classes of states which are inequivalent under the action of the local Pauli group. Finally we disclose a one-to-one correspondence with states employed in quantum algorithms, such as Deutsch–Jozsa's and Grover's.

Journal ArticleDOI
TL;DR: In this article, the optical forces and torques exerted on a chiral dipole by chiral light fields and reveal genuine chiral forces in combining the chiral contents of both light field and dipolar matter.
Abstract: We calculate optical forces and torques exerted on a chiral dipole by chiral light fields and reveal genuine chiral forces in combining the chiral contents of both light field and dipolar matter. Here, the optical chirality is characterized in a general way through the definition of optical chirality density and chirality flow. We show, in particular, that both terms have mechanical effects associated, respectively, with reactive and dissipative components of the chiral forces. Remarkably, these chiral force components are directly related to standard observables: optical rotation for the reactive component and circular dichroism for the dissipative one. As a consequence, the resulting forces and torques are dependent on the enantiomeric form of the chiral dipole. This suggests promising strategies for using chiral light forces to mechanically separate chiral objects according to their enantiomeric form.

Journal ArticleDOI
TL;DR: In this article, the macroscopic effect in filamentation that governs terahertz (THz) output energy yields and radiation profiles in the far field has been investigated in two-color laser filamentation using terawatt (TW) lasers.
Abstract: We investigate high-power terahertz (THz) generation in two-color laser filamentation using terawatt (TW) lasers including a 0.5?TW, 1?kHz system, as well as 2 and 30?TW systems both operating at 10?Hz. With these lasers, we study the macroscopic effect in filamentation that governs THz output energy yields and radiation profiles in the far field. We also characterize the radiation spectra at a broad range of frequencies covering radio?micro-waves to infrared frequencies. In particular, our 1?kHz THz source can provide high-energy (>1??J), high average power (>1?mW), intense (>1?MV?cm?1) and broadband (0.01?60?THz) THz radiation via two-color filamentation in air. Based on our scaling law, an ?30?TW laser can produce >0.1?mJ of THz radiation with multi-gigawatt peak power in ?1.5?m long filamentation.

Journal ArticleDOI
TL;DR: Using the Perdew-Burke-Ernzerhof (PBE), PBE+vdW (van der Waals) and the recently developed PBE +vdW surf (density-functional theory with vdW interactions that include the collective electronic response of the substrate) methods, this article calculated the structures and energy properties for benzene on transition-metal surfaces: Cu, Ag, Au, Pd, Pt, Rh and Ir.
Abstract: The adsorption of benzene on metal surfaces is an important bench- mark system for hybrid inorganic/organic interfaces. The reliable determination of the interface geometry and binding energy presents a significant challenge for both theory and experiment. Using the Perdew-Burke-Ernzerhof (PBE), PBE+vdW (van der Waals) and the recently developed PBE+vdW surf (density- functional theory with vdW interactions that include the collective electronic response of the substrate) methods, we calculated the structures and energet- ics for benzene on transition-metal surfaces: Cu, Ag, Au, Pd, Pt, Rh and Ir. Our calculations demonstrate that vdW interactions increase the binding en- ergy by more than 0.70eV for physisorbed systems (Cu, Ag and Au) and by an even larger amount for strongly bound systems (Pd, Pt, Rh and Ir). The collective response of the substrate electrons captured via the vdW surf method plays a significant role for most substrates, shortening the equilibrium dis- tance by 0.25A for Cu and decreasing the binding energy by 0.27eV for Rh. The reliability of our results is assessed by comparison with calculations using the random-phase approximation including renormalized single excitations,

Journal ArticleDOI
TL;DR: In this article, a particle-conditioned fluid velocity field is computed for turbulent open channel flow over a smooth horizontal wall in the presence of finite-size, heavy particles, where the particles preferentially reside in the low-speed streaks, leading to the observed apparent lag.
Abstract: We have performed direct numerical simulation of turbulent open channel flow over a smooth horizontal wall in the presence of finite-size, heavy particles. The spherical particles have a diameter of approximately 7 wall units, a density of 1.7 times the fluid density and a solid volume fraction of 5◊10 4 . The value of the Galileo number is set to 16.5, while the Shields parameter measures approximately 0.2. Under these conditions, the particles are predominantly located in the vicinity of the bottom wall, where they exhibit strong preferential concentration which we quantify by means of Voronoi analysis and by computing the particle-conditioned concentration field. As observed in previous studies with similar parameter values, the mean streamwise particle velocity is smaller than that of the fluid. We propose a new definition of the fluid velocity 'seen' by finite-size particles based on an average over a spherical surface segment, from which we deduce in the present case that the particles are instantaneously lagging the fluid only by a small amount. The particle-conditioned fluid velocity field shows that the particles preferentially reside in the low-speed streaks, leading to the observed apparent lag. Finally, a vortex eduction study reveals that spanwise particle motion is significantly correlated with the presence of vortices with the corresponding sense of rotation which are located in the immediate vicinity of the near-wall particles.

Journal ArticleDOI
TL;DR: In this article, a quantum Cheshire Cat is found in one place and its grin in another, and the Cat is a photon, while the grin is its circular polarization, in a pre-and post-selected experiment.
Abstract: In this paper we present a quantum Cheshire Cat. In a pre- and post-selected experiment we find the Cat in one place, and its grin in another. The Cat is a photon, while the grin is its circular polarization.

Journal ArticleDOI
TL;DR: In this article, an environment for 87Rb Bose-Einstein condensates where the constituent atoms behaved like relativistic particles subject to the one-dimensional Dirac equation was studied.
Abstract: Zitterbewegung, a force-free trembling motion first predicted for relativistic fermions like electrons, was an unexpected consequence of the Dirac equation's unification of quantum mechanics and special relativity. Though the oscillatory motion's large frequency and small amplitude have precluded its measurement with electrons, zitterbewegung is observable via quantum simulation. We engineered an environment for 87Rb Bose–Einstein condensates where the constituent atoms behaved like relativistic particles subject to the one-dimensional Dirac equation. With direct imaging, we observed the sub-micrometre trembling motion of these clouds, demonstrating the utility of neutral ultracold quantum gases for simulating Dirac particles.

Journal ArticleDOI
TL;DR: A way is shown to extend the techniques originally proposed in Demkowicz-Dobrza?ski et?al, so that they can be efficiently applied not only in the asymptotic but also in the finite number of particles regime, where quantum enhancement amounts to a constant factor improvement.
Abstract: Quantum metrology offers enhanced performance in experiments on topics such as gravitational wave-detection, magnetometry or atomic clock frequency calibration. The enhancement, however, requires a delicate tuning of relevant quantum features, such as entanglement or squeezing. For any practical application, the inevitable impact of decoherence needs to be taken into account in order to correctly quantify the ultimate attainable gain in precision. We compare the applicability and the effectiveness of various methods of calculating the ultimate precision bounds resulting from the presence of decoherence. This allows us to place a number of seemingly unrelated concepts into a common framework and arrive at an explicit hierarchy of quantum metrological methods in terms of the tightness of the bounds they provide. In particular, we show a way to extend the techniques originally proposed in Demkowicz-Dobrza?ski et?al (2012 Nature Commun. 3 1063), so that they can be efficiently applied not only in the asymptotic but also in the finite number of particles regime. As a result, we obtain a simple and direct method, yielding bounds that interpolate between the quantum enhanced scaling characteristic for a small number of particles and the asymptotic regime, where quantum enhancement amounts to a constant factor improvement. Methods are applied to numerous models, including noisy phase and frequency estimation, as well as the estimation of the decoherence strength itself.

Journal ArticleDOI
TL;DR: Results suggest that physiological fluid shear force can modulate receptor-mediated apoptosis of cancer cells in the presence of apoptotic agents.
Abstract: Cancer metastasis, the process of cancer cell migration from a primary to distal location, typically leads to a poor patient prognosis. Hematogenous metastasis is initiated by intravasation of circulating tumor cells (CTCs) into the bloodstream, which are then believed to adhere to the luminal surface of the endothelium and extravasate into distal locations. Apoptotic agents such as tumor necrosis factor (TNF) apoptosis-inducing ligand (TRAIL), whether in soluble ligand form or expressed on the surface of natural killer (NK) cells, have shown promise in treating CTCs to reduce the probability of metastasis. The role of hemodynamic shear forces in altering the cancer cell response to receptor-mediated apoptosis has not been previously investigated. Here, we report that human colon cancer COLO 205 and prostate cancer PC-3 cells exposed to a uniform fluid shear stress in a cone-and-plate viscometer become sensitized to TRAIL-induced apoptosis. Shear-induced sensitization directly correlated with the application of fluid shear stress, and TRAIL-induced apoptosis increased in a fluid shear stress force- and time-dependent manner. In contrast, TRAIL-induced necrosis was not affected by the application fluid shear stress. Interestingly, fluid shear stress did not sensitize cancer cells to apoptosis when treated with doxorubicin, which also induces apoptosis in cancer cells. Caspase inhibition experiments revealed that shear stress-induced sensitization to TRAIL occurs via caspase-dependent apoptosis. These results suggest that physiological fluid shear force can modulate receptor-mediated apoptosis of cancer cells in the presence of apoptotic agents.

Journal ArticleDOI
TL;DR: The unique fluctuation-dissipation theorem for equilibrium stands in contrast with a wide variety of nonequilibrium linear response formulae as discussed by the authors, which, in the absence of detailed balance, introduces the logarithm of the stationary probability density as observable.
Abstract: The unique fluctuation–dissipation theorem for equilibrium stands in contrast with the wide variety of nonequilibrium linear response formulae. Their most traditional approach is ‘analytic’, which, in the absence of detailed balance, introduces the logarithm of the stationary probability density as observable. The theory of dynamical systems offers an alternative with a formula that continues to work even when the stationary distribution is not smooth. We show that this method works equally well for stochastic dynamics, and we illustrate it with a numerical example for the perturbation of circadian cycles. A second ‘probabilistic’ approach starts from dynamical ensembles and expands the probability weights on path space. This line suggests new physical questions, as we meet the frenetic contribution to linear response, and the relevance of the change in dynamical activity in the relaxation to a (new) nonequilibrium condition.

Journal ArticleDOI
TL;DR: In this paper, a classification of topologically stable Fermi surfaces in (semi-)metals and nodal lines in superconductors is derived using K-theory.
Abstract: We systematically study gapless topological phases of (semi-)metals and nodal superconductors described by Bloch and Bogoliubov–de Gennes Hamiltonians. Using K-theory, a classification of topologically stable Fermi surfaces in (semi-)metals and nodal lines in superconductors is derived. We discuss a generalized bulk–boundary correspondence that relates the topological features of the Fermi surfaces and superconducting nodal lines to the presence of protected zero-energy states at the boundary of the system. Depending on the case, the boundary states are either linearly dispersing (i.e. Dirac or Majorana states) or dispersionless, forming two-dimensional surface flat bands or one-dimensional arc surface states. We study examples of gapless topological phases in symmetry classes AIII and DIII, focusing in particular on nodal superconductors, such as nodal noncentrosymmetric superconductors. For some cases we explicitly compute the surface spectrum and examine the signatures of the topological boundary states in the surface density of states. We also discuss the robustness of the surface states against disorder.

Journal ArticleDOI
TL;DR: Using the random phase approximation with both real space and discrete electron-hole (e-h) pair basis sets, the broadening of surface plasmons in metal structures of reduced dimensionality was studied in this paper.
Abstract: Using the random phase approximation with both real space and discrete electron–hole (e–h) pair basis sets, we study the broadening of surface plasmons in metal structures of reduced dimensionality, where Landau damping is the dominant dissipation channel and presents an intrinsic limitation to plasmonics technology We show that for every prototypical class of systems considered, including zero-dimensional nanoshells, one-dimensional coaxial nanotubes and two-dimensional ultrathin films, Landau damping can be drastically tuned due to energy quantization of the individual electron levels and e–h pairs Both the generic trend and oscillatory nature of the tunability are in stark contrast with the expectations of the semiclassical surface scattering picture Our approach also allows to vividly depict the evolution of the plasmons from the quantum to the classical regime, and to elucidate the underlying physical origin of hybridization broadening of nearly degenerate plasmon modes These findings may serve as a guide in the future design of plasmonic nanostructures of desirable functionalities

Journal ArticleDOI
TL;DR: A quantum algorithm and a scalable quantum circuit design which approximates the solution of the Poisson equation on a grid with error e and produces a quantum state encoding the solution.
Abstract: The Poisson equation occurs in many areas of science and engineering. Here we focus on its numerical solution for an equation in d dimensions. In particular we present a quantum algorithm and a scalable quantum circuit design which approximates the solution of the Poisson equation on a grid with error e. We assume we are given a superposition of function evaluations of the right-hand side of the Poisson equation. The algorithm produces a quantum state encoding the solution. The number of quantum operations and the number of qubits used by the circuit is almost linear in d and polylog in e−1. We present quantum circuit modules together with performance guarantees which can also be used for other problems.

Journal ArticleDOI
TL;DR: It is found that MDI-QKD is highly practical and thus can be easily implemented with standard optical devices, and a simple analytical method with only two decoy states for the finite decoy-state analysis is presented.
Abstract: A novel protocol, measurement-device-independent quantum key distribution (MDI-QKD), removes all attacks from the detection system, the most vulnerable part in QKD implementations. In this paper, we present an analysis for practical aspects of MDI-QKD. To evaluate its performance, we study various error sources by developing a general system model. We find that MDI-QKD is highly practical and thus can be easily implemented with standard optical devices. Moreover, we present a simple analytical method with only two (general) decoy states for the finite decoy-state analysis. This method can be used directly by experimentalists to demonstrate MDI-QKD. By combining the system model with the finite decoy-state method, we present a general framework for the optimal choice of the intensities of the signal and decoy states. Furthermore, we consider a common situation, namely asymmetric MDI-QKD, in which the two quantum channels have different transmittances. We investigate its properties and discuss how to optimize its performance. Our work is of interest not only to experiments demonstrating MDI-QKD but also to other non-QKD experiments involving quantum interference.