Journal ArticleDOI
A silver-based metal–organic framework material as a ‘reservoir’ of bactericidal metal ions
Mathieu Berchel,Tony Le Gall,Céline Denis,Sophie Le Hir,François Quentel,Catherine Elleouet,Tristan Montier,Jean-Michel Rueff,Jean-Yves Salaün,Jean-Pierre Haelters,Gary B. Hix,Pierre Lehn,Paul-Alain Jaffrès +12 more
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TLDR
In this article, the silver-based MOF material Ag3(3phosphonobenzoate) was evaluated as a bactericidal material and a sustainable release of Ag+, which was quantified by cathodic stripping voltammetry, was responsible for bactericidal activity against the 6 bacterial strains tested.Abstract:
The silver-based MOF material Ag3(3-phosphonobenzoate) was evaluated as a bactericidal material. A sustainable release of Ag+, which was quantified by cathodic stripping voltammetry, was responsible for bactericidal activity against the 6 bacterial strains tested.read more
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Metal-Organic Frameworks for Biomedical Applications.
TL;DR: This work outlines the synthesis and functionalization and the recent advances of MOFs in biomedical fields, including cargo (drugs, nucleic acids, proteins, and dyes) delivery for cancer therapy, bioimaging, antimicrobial, biosensing, and biocatalysis.
Journal ArticleDOI
Metal-organic frameworks: mechanisms of antibacterial action and potential applications.
TL;DR: Metal-organic frameworks are porous, hybrid materials comprising metal ions linked by organic binding ligands that can act as a reservoir of metal ions, providing their gradual release and resulting in a sustained antibacterial action analogous to that proposed for metal/metal oxide nanoparticles but different to that of antibiotics.
Journal ArticleDOI
Silver carboxylate metal-organic frameworks with highly antibacterial activity and biocompatibility.
Xinyi Lu,Junwei Ye,Dekui Zhang,Ruixia Xie,Raji Feyisa Bogale,Yuan Sun,Limei Zhao,Qi Zhao,Guiling Ning +8 more
TL;DR: Hematological study showed that these Ag-based metal-organic frameworks exhibit good biocompatibility in mice and good thermal stability and optical stability under UV-visible and visible light are beneficial for their antibacterial application.
Journal ArticleDOI
Extension of the Universal Force Field to Metal-Organic Frameworks.
TL;DR: This work has extended the UFF parameter set to include transition metal elements Zn, Cu, Ni, Co, Fe, Mn, Cr, V, Ti, Sc, and Al, as they occur in MOFs, and has proposed additional O parameters that provide reliable structures of the metal oxide clusters of the connectors.
Journal ArticleDOI
Metal organic frameworks based on bioactive components.
TL;DR: This review highlights the latest advances in 3D bioMOF structures, from their synthesis to their biorelated activities in differentBiorelated areas including drug delivery, imaging, and sensing, classifying them by the nature of the active component.
References
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Journal ArticleDOI
A mechanistic study of the antibacterial effect of silver ions on Escherichia coli and Staphylococcus aureus.
TL;DR: The existence of elements of silver and sulfur in the electron-dense granules and cytoplasm detected by X-ray microanalysis suggested the antibacterial mechanism of silver: DNA lost its replication ability and the protein became inactivated after Ag(+) treatment.
Journal ArticleDOI
Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging
Patricia Horcajada,Tamim Chalati,Christian Serre,Brigitte Gillet,Catherine Sebrié,Tarek Baati,Jarrod F. Eubank,Daniela Heurtaux,Pascal Clayette,Christine Kreuz,Jong-San Chang,Young Kyu Hwang,Véronique Marsaud,Phuong-Nhi Bories,Luc Cynober,Sophie Gil,Gérard Férey,Patrick Couvreur,Ruxandra Gref +18 more
TL;DR: It is shown that specific non-toxic porous iron(III)-based metal-organic frameworks with engineered cores and surfaces, as well as imaging properties, function as superior nanocarriers for efficient controlled delivery of challenging antitumoural and retroviral drugs against cancer and AIDS.
Journal ArticleDOI
Secondary building units, nets and bonding in the chemistry of metal–organic frameworks
TL;DR: The geometries of 131 SBUs, their connectivity and composition of transition-metal carboxylate clusters which may serve as secondary building units (SBUs) towards construction and synthesis of metal-organic frameworks (MOFs).
Journal ArticleDOI
Whole genome sequencing of meticillin-resistant Staphylococcus aureus
Makoto Kuroda,Toshiko Ohta,Ikuo Uchiyama,Tadashi Baba,Harumi Yuzawa,Ichizo Kobayashi,Longzhu Cui,Akio Oguchi,Ken-ichi Aoki,Yoshimi Nagai,JianQi Lian,Teruyo Ito,Mutsumi Kanamori,Hiroyuki Matsumaru,Atsushi Maruyama,Hiroyuki Murakami,Akira Hosoyama,Yoko Mizutani-Ui,Noriko K. Takahashi,Toshihiko Sawano,Ryu-ichi Inoue,Chikara Kaito,Kazuhisa Sekimizu,Hideki Hirakawa,Satoru Kuhara,Susumu Goto,Junko Yabuzaki,Minoru Kanehisa,Atsushi Yamashita,Kenshiro Oshima,Keiko Furuya,Chie Yoshino,Tadayoshi Shiba,Masahira Hattori,Naotake Ogasawara,Hideo Hayashi,Keiichi Hiramatsu +36 more
TL;DR: Investigation of many newly identified gene products, including the 70 putative virulence factors, will greatly improve the understanding of the biology of staphylococci and the processes of infectious diseases caused by S aureus.
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Silver carboxylate metal-organic frameworks with highly antibacterial activity and biocompatibility.
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Patricia Horcajada,Tamim Chalati,Christian Serre,Brigitte Gillet,Catherine Sebrié,Tarek Baati,Jarrod F. Eubank,Daniela Heurtaux,Pascal Clayette,Christine Kreuz,Jong-San Chang,Young Kyu Hwang,Véronique Marsaud,Phuong-Nhi Bories,Luc Cynober,Sophie Gil,Gérard Férey,Patrick Couvreur,Ruxandra Gref +18 more