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Open AccessJournal ArticleDOI

Administrative Coding in Electronic Health Care Record-Based Research of NAFLD: An Expert Panel Consensus Statement

TLDR
The lack of consensus on which International Classification of Disease (ICD) codes should be used as exposures and outcomes limits comparability and generalizability of results across studies as discussed by the authors.
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This article is published in Hepatology.The article was published on 2021-01-23 and is currently open access. It has received 60 citations till now.

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Journal ArticleDOI

Advancing the global public health agenda for NAFLD: a consensus statement.

TL;DR: In this paper, a global Delphi study, a multidisciplinary group of experts developed consensus statements and recommendations, which a larger group of collaborators reviewed over three rounds until consensus was achieved.
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The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality

TL;DR: The European Association for the Study of the Liver (EASL) proposed a framework for the principal actions required to improve liver health in Europe as mentioned in this paper , which can serve as a powerful mechanism for improving liver care in Europe.
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Angiotensin‐converting enzyme inhibitors prevent liver‐related events in nonalcoholic fatty liver disease

TL;DR: In this article , the authors evaluated the impact of ACEI/ARB use on the risk of liver cancer and cirrhosis complications in patients with NAFLD and found that ACEI treatment was associated with a lower risk of LREs.
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Glucagon-Like Peptide 1 Receptor Agonists and Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Nonalcoholic Fatty Liver Disease Among Patients With Type 2 Diabetes.

TL;DR: SGLT-2 inhibitors, and possibly GLP-1 RA, may be associated with a decreased incidence of NAFLD and hepatic transaminase elevation among patients with type 2 diabetes.
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Risk of cardiovascular disease and loss in life expectancy in NAFLD

TL;DR: Examination of CVD risk and life expectancy in patients with NAFLD compared with the general population found no change in either risk or life expectancy.
References
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EASL-EASD-EASO Clinical Practice Guidelines for the Management of Non-Alcoholic Fatty Liver Disease

TL;DR: The final purpose is to improve patient care and awareness of the importance of NAFLD, and to assist stakeholders in the decision-making process by providing evidence-based data, which also takes into consideration the burden of clinical management for the healthcare system.
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Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up.

TL;DR: NAFLD patients have increased risk of death, with a high risk ofdeath from cardiovascular disease and liver‐related disease, and the NAS was not able to predict overall mortality, whereas fibrosis stage predicted both overall and disease‐specific mortality.
Journal ArticleDOI

Defining consensus: A systematic review recommends methodologic criteria for reporting of Delphi studies

TL;DR: Investigation of how consensus is operationalized in Delphi studies and the role of consensus in determining the results of these studies finds definitions of consensus vary widely and are poorly reported.
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