Journal ArticleDOI
Biological importance of the indole nucleus in recent years: A comprehensive review
TLDR
Indole has a benzene ring and pyrrole ring sharing one double bond and is a heterocyclic system with 10 electrons from four double bonds and the lone pair from the nitrogen atom as mentioned in this paper.About:
This article is published in Journal of Heterocyclic Chemistry.The article was published on 2010-05-01. It has received 385 citations till now. The article focuses on the topics: Indole test & Ring (chemistry).read more
Citations
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Synthesis and Characterization of Red and Near-Infrared BODIPY-based fluorophores for various Biological Applications
TL;DR: The present study focuses on the application of BODIPY dyes in the context of textiles and investigates the role of nanofiltration in the response of these colours to various materials.
Journal ArticleDOI
Highly selective Diels-Alder and Heck arylation reactions in a divergent synthesis of isoindolo- and pyrrolo-fused polycyclic indoles from 2-formylpyrrole.
Carlos H. Escalante,Eder I. Martínez-Mora,Eder I. Martínez-Mora,Carlos Espinoza-Hicks,Alejandro Camacho-Dávila,Fernando R. Ramos-Morales,Francisco Delgado,Joaquín Tamariz +7 more
TL;DR: A theoretical study on the stereoselective Diels–Alder reactions, carried out by calculating the endo/exo transition states, revealed the assistance of non-covalent interactions in governing theendo stereocontrol.
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Design, Synthesis and Characterization of Novel Isoxazole Tagged Indole Hybrid Compounds
Raed A. Al-Qawasmeh,Raed A. Al-Qawasmeh,Louy A. Al-Nazer,Sarah A. Dawlat-Kari,Luay Abu-Qatouseh,Salim S. Sabri,Murad A. AlDamen,Mutasem Omar Sinnokrot +7 more
TL;DR: In this paper, 16 new isoxazole tagged indole compounds have been synthesized via copper catalyzed click chemistry of the aryl hydroxamoyl chloride and an indole containing alkyne moiety.
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Zinc Chloride Catalyzed Amino Claisen Rearrangement of 1-N-Allylindolines: An Expedient Protocol for the Synthesis of Functionalized 7-Allylindolines
TL;DR: In this article, the rearrangement is influenced by stereoelectronic effects of substituents present in 1-N-allylindolines and ZnCl2 catalyst loading in the reaction system.
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Palladium(II)-catalyzed tandem cyclization of 2-ethynylaniline tethered cinnamyl acetate for the synthesis of indenoindoles
Junjie Chen,Xiuling Han,Xiyan Lu +2 more
TL;DR: A palladium(ii)-catalyzed cyclization of 2-ethynylaniline tethered cinnamyl acetate involving aminopalladation/alkene insertion/β-acetoxy elimination cascade processes was established, providing efficient access to indenoindoles in moderate to good yields under mild conditions.
References
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Journal ArticleDOI
Synthesis and biological evaluation of new 3-substituted indole derivatives as potential anti-inflammatory and analgesic agents.
TL;DR: The newly synthesized compounds were found to possess potential anti-inflammatory and analgesic activities and to be compatible with existing thiazolidin-4-one derivatives.
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Synthesis and structure–antituberculosis activity relationship of 1H-indole-2,3-dione derivatives
Nilgün Karalı,Aysel Gürsoy,Fatma Kandemirli,Nathaly Shvets,F. Betül Kaynak,Süheyla Özbey,Vasyl Kovalishyn,Anatholy Dimoglo,Anatholy Dimoglo +8 more
TL;DR: The antituberculosis activity of molecules with diverse skeletons was investigated by means of the Electronic-Topological Method (ETM) and Artificial Neural Networks were used after the ETM to obtain the algorithmic base for the activity prediction.
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Synthesis and antiinflammatory activity of heterocyclic indole derivatives.
TL;DR: The most active compound, 3-[1-acetyl-5-(p-hydroxyphenyl)-2-pyrazolin-3-yl]indole (7) was found to be most potent, which has shown higher percent of inhibition of oedema, lower ulcerogenic liability and acute toxicity than the standard drug phenylbutazone.
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Antioxidant activity of 5,10-dihydroindeno[1,2-b]indoles containing substituents on dihydroindeno part.
TL;DR: An efficient synthesis of 5,10-dihydroindeno[1,2-b]indoles (3a-t) containing substituents such as methoxy, hydroxyl, and halogen on indeno part showed effective antioxidant power.
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Indole and Isatin Oximes: Synthesis, Reactions, and Biological Activity. (Review)
TL;DR: In this article, data on methods for the production of isatin and indole aldoximes, ketoxime, and amidoximes and their reactions are reviewed, and individual syntheses of new heterocycles from indole and isatin oximes are discussed.