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Biological measurement beyond the quantum limit

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TLDR
In this paper, the authors used squeezed light to track the constituents of yeast cells with a performance that overcomes the quantum noise limit, which allows for the utilization of low optical power, which helps to minimize cell damage.
Abstract
Researchers use squeezed light to track the constituents of yeast cells with a performance that overcomes the quantum noise limit. This approach allows for the utilization of low optical power, which helps to minimize cell damage.

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Citations
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Higher order mode entanglement in a type II optical parametric oscillator.

TL;DR: The relation between pump modes and entanglement of first-order Hermite Gauss modes (HG10 entangled states) in a type II OPO is experimentally demonstrated and it is shown that the maximum entangled states can be obtained by optimizing the pump spatial mode.
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Number-unconstrained quantum sensing

TL;DR: In this paper, the authors develop the theory of particle-number-unconstrained quantum sensing, and describe how optimal particle numbers emerge from the competition of particleenvironment and particleparticle interactions.
Journal ArticleDOI

Squeezing in the quantum Rabi model with parametric nonlinearity

TL;DR: In this paper, the authors studied the squeezing effect arising in the interacting qubit-oscillator system with the presence of a parametric oscillator in the Rabi model and employed the generalized rotating wave approximation which works well in a wide range of coupling strength as well as detuning.
Posted Content

Quantum correlations overcome the photodamage limits of light microscopy

TL;DR: In this paper, a coherent Raman microscopy was used to image molecular bonds within a cell with both quantumenhanced contrast and sub-wavelength resolution. But the performance of the coherent microscopy is limited by photodamage.
Journal ArticleDOI

A computational tool to characterize particle tracking measurements in optical tweezers

TL;DR: In this paper, the authors present a computational tool for optical tweezers which calculates the particle tracking signal measured with a quadrant detector and the shot-noise limit to position resolution.
References
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Journal ArticleDOI

Quantum-enhanced measurements: beating the standard quantum limit.

TL;DR: This work has shown that conventional bounds to the precision of measurements such as the shot noise limit or the standard quantum limit are not as fundamental as the Heisenberg limits and can be beaten using quantum strategies that employ “quantum tricks” such as squeezing and entanglement.
Journal ArticleDOI

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

TL;DR: These techniques are described and illustrated with examples highlighting current capabilities and limitations of single-molecule force spectroscopy.
Journal ArticleDOI

Optical Trapping and Manipulation of Viruses and Bacteria

Arthur Ashkin, +1 more
- 20 Mar 1987 - 
TL;DR: Trapping and manipulation of single live motile bacteria and Escherichia coli bacteria were demonstrated in a high-resolution microscope at powers of a few milliwatts.
Journal ArticleDOI

Direct observation of kinesin stepping by optical trapping interferometry

TL;DR: It is found that kinesin moves with 8-nm steps, similar to biological motors that move with regular steps.
Journal ArticleDOI

Single myosin molecule mechanics: piconewton forces and nanometre steps

TL;DR: A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results from the interaction of a single myosin molecule with a single suspended actin filament.
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