Biological measurement beyond the quantum limit
Michael A. Taylor,Jiri Janousek,Vincent Ricardo Daria,Joachim Knittel,Boris Hage,Hans-A. Bachor,Warwick P. Bowen +6 more
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In this paper, the authors used squeezed light to track the constituents of yeast cells with a performance that overcomes the quantum noise limit, which allows for the utilization of low optical power, which helps to minimize cell damage.Abstract:
Researchers use squeezed light to track the constituents of yeast cells with a performance that overcomes the quantum noise limit. This approach allows for the utilization of low optical power, which helps to minimize cell damage.read more
Citations
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Fundamental constraints on particle tracking with optical tweezers
TL;DR: In this paper, a general quantum limit to the sensitivity of particle position measurements is derived following the simple principle of the Heisenberg microscope, and the value of this limit is calculated for particles in the Rayleigh and Mie scattering regimes, and with parameters which are relevant to optical tweezers experiments.
Journal ArticleDOI
Geometry controlled anomalous diffusion in random fractal geometries: looking beyond the infinite cluster.
TL;DR: In this article, the ergodic properties of a random walker performing (anomalous) diffusion on a random fractal geometry were investigated, and the convergence scaling law to ergodicity, which is known to be inversely proportional to the observation time T, was shown to follow a power-law ∼T−h with h < 1.
Journal ArticleDOI
Thermally induced micro-motion by inflection in optical potential.
TL;DR: An experimental set-up of holographic optical tweezers is exploited to experimentally investigate Brownian motion of a micro-particle near the inflection point of the cubic optical potential to evaluate specific statistical moment ratios demonstrating strongly non-linear stochastic dynamics.
Journal ArticleDOI
Efficient photon triplet generation in integrated nanophotonic waveguides.
Moebius Michael G,Felipe Herrera,Sarah Griesse-Nascimento,Orad Reshef,Christopher C. Evans,Gian Giacomo Guerreschi,Alán Aspuru-Guzik,Eric Mazur +7 more
TL;DR: The use of integrated nanophotonics to enhance nonlinear interactions and protocols to design multimode waveguides that enable sustained phase-matching for third-order spontaneous parametric down-conversion (TOSPDC) are developed.
Journal ArticleDOI
Anomalous transport of subdiffusing cargos by single kinesin motors: the role of mechano-chemical coupling and anharmonicity of tether.
TL;DR: In this paper, the authors generalize their previous model of molecular motors trafficking subdiffusing cargos in viscoelastic cytosol by taking into account the anharmonicity of the tether between the motor and the cargo (its maximally possible extension length).
References
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Quantum-enhanced measurements: beating the standard quantum limit.
TL;DR: This work has shown that conventional bounds to the precision of measurements such as the shot noise limit or the standard quantum limit are not as fundamental as the Heisenberg limits and can be beaten using quantum strategies that employ “quantum tricks” such as squeezing and entanglement.
Journal ArticleDOI
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy
Keir C. Neuman,Attila Nagy +1 more
TL;DR: These techniques are described and illustrated with examples highlighting current capabilities and limitations of single-molecule force spectroscopy.
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Optical Trapping and Manipulation of Viruses and Bacteria
Arthur Ashkin,J. M. Dziedzic +1 more
TL;DR: Trapping and manipulation of single live motile bacteria and Escherichia coli bacteria were demonstrated in a high-resolution microscope at powers of a few milliwatts.
Journal ArticleDOI
Direct observation of kinesin stepping by optical trapping interferometry
TL;DR: It is found that kinesin moves with 8-nm steps, similar to biological motors that move with regular steps.
Journal ArticleDOI
Single myosin molecule mechanics: piconewton forces and nanometre steps
TL;DR: A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results from the interaction of a single myosin molecule with a single suspended actin filament.
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Puncken,V. Quetschke,E. A. Quintero,R. Quitzow-James,F. J. Raab,H. Radkins,P. Raffai,S. Raja,Malik Rakhmanov,C. R. Ramet,V. Raymond,C. M. Reed,T. Reed,Stuart Reid,D. H. Reitze,R. Riesen,K. Riles,Mallory S. E. Roberts,N. A. Robertson,N. A. Robertson,Emma L. Robinson,S. Roddy,Carl L. Rodriguez,L. Rodriguez,M. Rodruck,J. G. Rollins,J. H. Romie,Christian Röver,Christian Röver,Sheila Rowan,Albrecht Rüdiger,Albrecht Rüdiger,Kris Ryan,Francesco Salemi,Francesco Salemi,L. Sammut,V. Sandberg,J. R. Sanders,S. Sankar,Virginio Sannibale,Lucía Santamaría,I. Santiago-Prieto,G. Santostasi,Bangalore Suryanarayana Sathyaprakash,Peter R. Saulson,R. L. Savage,Roland Schilling,Roland Schilling,Roman Schnabel,Roman Schnabel,R. M. S. Schofield,D. Schuette,D. Schuette,Bastian Schulz,Bastian Schulz,Bernard F. Schutz,Bernard F. Schutz,P. Schwinberg,John D. Scott,Susan M. Scott,F. Seifert,D. Sellers,A. S. Sengupta,A. M. Sergeev,Daniel A. Shaddock,M. S. Shahriar,M. Shaltev,M. Shaltev,Z. Shao,B. Shapiro,P. Shawhan,David H. Shoemaker,Trevor Sidery,Xavier Siemens,D. Sigg,D. Simakov,D. Simakov,A. Singer,Leo Singer,Alicia M. Sintes,G. R. Skelton,B. J. J. Slagmolen,Jacob Slutsky,Jacob Slutsky,J. R. Smith,M. R. Smith,R. J.E. Smith,N. D. Smith-Lefebvre,Edwin J. Son,B. Sorazu,Tarun Souradeep,M. Stefszky,E. Steinert,Jessica Steinlechner,Jessica Steinlechner,Sebastian Steinlechner,Sebastian Steinlechner,S. Steplewski,Douglas E. Stevens,A. Stochino,Robert Stone,Kenneth A. Strain,S. E. Strigin,A. S. Stroeer,A. L. Stuver,T. Z. Summerscales,Sunil Susmithan,Patrick J. Sutton,G. Szeifert,D. Talukder,David B. Tanner,S. P. Tarabrin,S. P. Tarabrin,R. Taylor,Michael Thomas,P. Thomas,K. A. Thorne,Kip S. Thorne,Eric Thrane,Vaibhav Tiwari,K. V. Tokmakov,C. Tomlinson,C. V. Torres,C. I. Torrie,C. I. Torrie,G. Traylor,M. Tse,D. Ugolini,C. S. Unnikrishnan,H. Vahlbruch,H. Vahlbruch,Michele Vallisneri,M. V. van der Sluys,A. A. van Veggel,S. Vass,Ruslan Vaulin,Alberto Vecchio,P. J. Veitch,John Veitch,K. 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