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Biological measurement beyond the quantum limit

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TLDR
In this paper, the authors used squeezed light to track the constituents of yeast cells with a performance that overcomes the quantum noise limit, which allows for the utilization of low optical power, which helps to minimize cell damage.
Abstract
Researchers use squeezed light to track the constituents of yeast cells with a performance that overcomes the quantum noise limit. This approach allows for the utilization of low optical power, which helps to minimize cell damage.

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Roadmap for optical tweezers

TL;DR: Optical tweezers are tools made of light that enable contactless pushing, trapping, and manipulation of objects, ranging from atoms to space light sails as discussed by the authors , and have been employed in a broad range of applications in the life sciences, physics, and engineering.
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An integrated quantum photonic sensor based on Hong-Ou-Mandel interference

TL;DR: A novel integrated Fock state optical sensor architecture that can be used for force, refractive index and possibly local temperature detection is proposed and found that linear optical quantum photonic architectures can achieve comparable sensor performance to semiclassical devices.
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Quantum Enhanced Precision Estimation of Transmission with Bright Squeezed Light

TL;DR: In this article, the authors demonstrate simultaneous enhancement of precision and sensitivity to beyond the quantum noise limit for estimating modulated transmission with a squeezed amplitude probe of $0.2$ mW average power, which is 8 orders of magnitude above the power limitations of previous sub-QNL precision measurements of transmission.
Journal ArticleDOI

Optimizing phase to enhance optical trap stiffness.

TL;DR: This work describes the achievable in-crease in trap stiffness and its dependence on particle size, refractive index, and optical polarization, and shows that phase-only control can achieve almost all of the enhancement possible with full wavefront shaping.
Journal ArticleDOI

Optical implementation of spin squeezing

TL;DR: In this paper, a model of optical spin-squeezing, which uses post-selection and photon subtraction from the state generated using a parametric downconversion photon source, was investigated.
References
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Journal ArticleDOI

Quantum-enhanced measurements: beating the standard quantum limit.

TL;DR: This work has shown that conventional bounds to the precision of measurements such as the shot noise limit or the standard quantum limit are not as fundamental as the Heisenberg limits and can be beaten using quantum strategies that employ “quantum tricks” such as squeezing and entanglement.
Journal ArticleDOI

Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy

TL;DR: These techniques are described and illustrated with examples highlighting current capabilities and limitations of single-molecule force spectroscopy.
Journal ArticleDOI

Optical Trapping and Manipulation of Viruses and Bacteria

Arthur Ashkin, +1 more
- 20 Mar 1987 - 
TL;DR: Trapping and manipulation of single live motile bacteria and Escherichia coli bacteria were demonstrated in a high-resolution microscope at powers of a few milliwatts.
Journal ArticleDOI

Direct observation of kinesin stepping by optical trapping interferometry

TL;DR: It is found that kinesin moves with 8-nm steps, similar to biological motors that move with regular steps.
Journal ArticleDOI

Single myosin molecule mechanics: piconewton forces and nanometre steps

TL;DR: A new in vitro assay using a feedback enhanced laser trap system allows direct measurement of force and displacement that results from the interaction of a single myosin molecule with a single suspended actin filament.
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