Journal ArticleDOI
Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects
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TLDR
Although many questions remain to be answered, it is becoming increasingly apparent that exposure to BPA is ubiquitous and that the effects of this endocrine disruptor are complex and wide-ranging.About:
This article is published in The Journal of Steroid Biochemistry and Molecular Biology.The article was published on 2011-10-01. It has received 1076 citations till now. The article focuses on the topics: Environmental exposure & Endocrine disruptor.read more
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Dissertation
Fate and effects of waterborne contaminants of emerging concern in the soil-plant system : impact of biochar soil amendment to mitigate their plant uptake
TL;DR: In this paper, a metabolomic approach was applied to correlate the presence of CECs with changes in the metabolome and the changes in chlorophyll content and plant morphology.
Journal ArticleDOI
Effects of 17 α-methyltestosterone on the transcriptome, gonadal histology and sex steroid hormones in Pseudorasbora parva.
TL;DR: It is found that 17α-methyltestosterone could inhibit the gonadal development of P. parva, and the growth and development of fish could be delayed by exposure to MT at 200 ng/L, which confirms the suitability of P-parva as a model fish for aquatic toxicological study and provides a multidimensional sight for the disruption effects of MT on fish.
Journal ArticleDOI
Differential methylation of genes in the human placenta associated with bisphenol A exposure.
Xiuxia Song,Ziliang Wang,Zhaofeng Zhang,Maohua Miao,Junwei Liu,Min Luan,Jing Du,Hong Liang,Wei Yuan +8 more
TL;DR: In this paper, the association between prenatal BPA exposure and DNA methylation in the placenta of 146 mother-infant pairs from the Shanghai-Minhang Birth Cohort Study was examined.
Journal ArticleDOI
Effect of inorganic and organic solutes on zero-valent aluminum-activated hydrogen peroxide and persulfate oxidation of bisphenol A
TL;DR: In the absence of the solutes, the PS/Z VA treatment system was superior to the HP/ZVA system in terms of BPA removal rates and kinetics, and the relative Vibrio fischeri photoluminescence inhibition decreased particularly for the PS /ZVA treatment system, which exhibited a higher treatment performance than the HP /Zva treatment system.
Journal ArticleDOI
Exposure to phthalates, phenols, and parabens mixture and alterations in sex steroid hormones among adolescents.
TL;DR: In this paper , the associations of exposure to phthalates (PAEs), phenols, and parabens biomarkers with sex hormones among participants aged 12-19 years old (n = 613).
References
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Journal ArticleDOI
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
George G. J. M. Kuiper,J.G. Lemmen,Bo Carlsson,J. Christopher Corton,Stephen Safe,Paul T. van der Saag,Bart van der Burg,Jan-Åke Gustafsson +7 more
TL;DR: The estrogenic activity of environmental chemicals and phytoestrogens in competition binding assays with ERα or ERβ protein, and in a transient gene expression assay using cells in which an acute estrogenic response is created by cotransfecting cultures with recombinant human ERβ complementary DNA (cDNA) in the presence of an estrogen-dependent reporter plasmid are investigated.
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Human exposure to bisphenol A (BPA).
TL;DR: The reported levels of BPA in human fluids are higher than the BPA concentrations reported to stimulate molecular endpoints in vitro and appear to be within an order of magnitude of the levels needed to induce effects in animal models.
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Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004
TL;DR: Urine concentrations of total BPA differed by race/ethnicity, age, sex, and household income, and these first U.S. population representative concentration data for urinary BPA and tOP should help guide public health research priorities.
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Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption
TL;DR: This review has covered the above-mentioned controversies plus six additional issues that have divided scientists in the field of BPA research, namely: mechanisms of bisphenol-A action; levels of human exposure; 3) routes of human Exposure; 4) pharmacokinetic models of Bpa metabolism; 5) effects of B PA on exposed animals; and 6) links between BPA and cancer.
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Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development.
TL;DR: This paper showed that maternal exposure to bisphenol A (BPA), a high-production-volume chemical used in the manufacture of polycarbonate plastic, is associated with higher body weight, increased breast and prostate cancer, and altered reproductive function.