Journal ArticleDOI
Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects
Reads0
Chats0
TLDR
Although many questions remain to be answered, it is becoming increasingly apparent that exposure to BPA is ubiquitous and that the effects of this endocrine disruptor are complex and wide-ranging.About:
This article is published in The Journal of Steroid Biochemistry and Molecular Biology.The article was published on 2011-10-01. It has received 1076 citations till now. The article focuses on the topics: Environmental exposure & Endocrine disruptor.read more
Citations
More filters
Journal ArticleDOI
Adsorption performance of modified agricultural waste materials for removal of emerging micro-contaminant bisphenol A: A comprehensive review.
TL;DR: The adsorption performance of different green adsorbents derived from agricultural waste materials (AWMs) that were used for the elimination of bisphenol A (BPA) from aqueous matrices is assessed.
Journal ArticleDOI
Impact of low-dose chronic exposure to bisphenol A and its analogue bisphenol B, bisphenol F and bisphenol S on hypothalamo-pituitary-testicular activities in adult rats: A focus on the possible hormonal mode of action.
Asad Ullah,Madeeha Pirzada,Sarwat Jahan,Hizb Ullah,Naheed Turi,Waheed Ullah,Mariyam Fatima Siddiqui,Muhammad Zakria,Kinza Zafar Lodhi,Muhammad Munir Khan +9 more
TL;DR: Exposure to BPA and its analogues for chronic duration can induce structural changes in testicular tissue and endocrine alterations in the male reproductive system, showing a significant alteration in the gonadosomatic index (GSI) and relative reproductive organs weights.
Journal ArticleDOI
Consortium-based science: the NIEHS's multipronged, collaborative approach to assessing the health effects of bisphenol A.
Linda S. Birnbaum,John R. Bucher,Gwen W. Collman,Darryl C. Zeldin,Anne F. Johnson,Thaddeus T. Schug,Jerrold J. Heindel +6 more
TL;DR: The NIEHS’s new consortium-based approach has led to more integrated, collaborative efforts and should improve the ability to resolve controversies over the potential human health effects of exposures to low levels of endocrine-active agents.
Journal ArticleDOI
Fetal growth in environmental epidemiology: mechanisms, limitations, and a review of associations with biomarkers of non-persistent chemical exposures during pregnancy.
TL;DR: To improve understanding of how everyday chemical exposures affect fetal growth, and ultimately lifelong health outcomes, mechanisms of toxicant action should be considered alongside improved study designs for future hypothesis-driven research.
Journal ArticleDOI
Effect of triclosan, triclocarban, 2,2′,4,4′-tetrabromodiphenyl ether, and bisphenol A on the iodide uptake, thyroid peroxidase activity, and expression of genes involved in thyroid hormone synthesis ☆
TL;DR: It is shown that triclosan, triclocarban, BDE-47, and BPA inhibited iodide uptake, but had differential effects on the expression of TH synthesis-related genes and the activity of TPO.
References
More filters
Journal ArticleDOI
Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.
George G. J. M. Kuiper,J.G. Lemmen,Bo Carlsson,J. Christopher Corton,Stephen Safe,Paul T. van der Saag,Bart van der Burg,Jan-Åke Gustafsson +7 more
TL;DR: The estrogenic activity of environmental chemicals and phytoestrogens in competition binding assays with ERα or ERβ protein, and in a transient gene expression assay using cells in which an acute estrogenic response is created by cotransfecting cultures with recombinant human ERβ complementary DNA (cDNA) in the presence of an estrogen-dependent reporter plasmid are investigated.
Journal ArticleDOI
Human exposure to bisphenol A (BPA).
TL;DR: The reported levels of BPA in human fluids are higher than the BPA concentrations reported to stimulate molecular endpoints in vitro and appear to be within an order of magnitude of the levels needed to induce effects in animal models.
Journal ArticleDOI
Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004
TL;DR: Urine concentrations of total BPA differed by race/ethnicity, age, sex, and household income, and these first U.S. population representative concentration data for urinary BPA and tOP should help guide public health research priorities.
Journal ArticleDOI
Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption
TL;DR: This review has covered the above-mentioned controversies plus six additional issues that have divided scientists in the field of BPA research, namely: mechanisms of bisphenol-A action; levels of human exposure; 3) routes of human Exposure; 4) pharmacokinetic models of Bpa metabolism; 5) effects of B PA on exposed animals; and 6) links between BPA and cancer.
Journal ArticleDOI
Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development.
TL;DR: This paper showed that maternal exposure to bisphenol A (BPA), a high-production-volume chemical used in the manufacture of polycarbonate plastic, is associated with higher body weight, increased breast and prostate cancer, and altered reproductive function.