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Journal ArticleDOI

Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects

Beverly S. Rubin
- 01 Oct 2011 - 
- Vol. 127, Iss: 1, pp 27-34
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TLDR
Although many questions remain to be answered, it is becoming increasingly apparent that exposure to BPA is ubiquitous and that the effects of this endocrine disruptor are complex and wide-ranging.
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This article is published in The Journal of Steroid Biochemistry and Molecular Biology.The article was published on 2011-10-01. It has received 1076 citations till now. The article focuses on the topics: Environmental exposure & Endocrine disruptor.

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Citations
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A post-genomic view of behavioral development and adaptation to the environment

TL;DR: The review is organized with respect to four basic processes by which phenotypes adapt to environmental challenges, with an emphasis on the data for humans: developmental plasticity, epigenetic mechanisms, genotype-environment correlations, and gene × environment interactions.
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Electrochemical switching with a DNA aptamer-based electrochemical sensor

TL;DR: The results revealed that BPA could be detected in a wide linear range from 1 to 600nM with a low detection limit down to 300pM, indicating that the present strategy was promising for broad potential application in clinic assay.
Journal ArticleDOI

Green approaches in the synthesis of furan-based diepoxy monomers

TL;DR: In this article, two eco-respectful, one-step synthetic routes for the preparation of a bio-based epoxy monomer derived from furan precursors are developed.
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Biobased Epoxy Resin by Electrochemical Modification of Tall Oil Fatty Acids

TL;DR: In this paper, a biobased epoxy resin was prepared from tall oil fatty acids (TOFAs), a byproduct of the pulping industry, and it was subjected to non-Kolbe decarboxylation to give alkenes upon loss of CO2.
References
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Journal ArticleDOI

Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.

TL;DR: The estrogenic activity of environmental chemicals and phytoestrogens in competition binding assays with ERα or ERβ protein, and in a transient gene expression assay using cells in which an acute estrogenic response is created by cotransfecting cultures with recombinant human ERβ complementary DNA (cDNA) in the presence of an estrogen-dependent reporter plasmid are investigated.
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Human exposure to bisphenol A (BPA).

TL;DR: The reported levels of BPA in human fluids are higher than the BPA concentrations reported to stimulate molecular endpoints in vitro and appear to be within an order of magnitude of the levels needed to induce effects in animal models.
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Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003-2004

TL;DR: Urine concentrations of total BPA differed by race/ethnicity, age, sex, and household income, and these first U.S. population representative concentration data for urinary BPA and tOP should help guide public health research priorities.
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Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption

TL;DR: This review has covered the above-mentioned controversies plus six additional issues that have divided scientists in the field of BPA research, namely: mechanisms of bisphenol-A action; levels of human exposure; 3) routes of human Exposure; 4) pharmacokinetic models of Bpa metabolism; 5) effects of B PA on exposed animals; and 6) links between BPA and cancer.
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Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development.

TL;DR: This paper showed that maternal exposure to bisphenol A (BPA), a high-production-volume chemical used in the manufacture of polycarbonate plastic, is associated with higher body weight, increased breast and prostate cancer, and altered reproductive function.
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