Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography
Sarah M. Friedewald,Elizabeth A. Rafferty,Stephen L. Rose,Melissa A. Durand,Donna Plecha,Julianne S. Greenberg,Mary Katherine Hayes,Debra S. Copit,Kara L. Carlson,Thomas M. Cink,Lora D. Barke,Linda N. Greer,Dave P. Miller,Emily F. Conant +13 more
TLDR
Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate, and further studies are needed to assess the relationship to clinical outcomes.Abstract:
mammography + tomosynthesis; difference, 1.3 (95% CI, 0.4-2.1; P = .004); for cancer detection, 4.2 (95% CI, 3.8-4.7) with digital mammography vs 5.4 (95% CI, 4.9-6.0) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001); and for invasive cancer detection, 2.9 (95% CI, 2.5-3.2) with digital mammography vs 4.1 (95% CI, 3.7-4.5) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001). The in situ cancer detection rate was 1.4 (95% CI, 1.2-1.6) per 1000 screens with both methods. Adding tomosynthesis was associated with an increase in the positive predictive value for recall from 4.3% to 6.4% (difference, 2.1%; 95% CI, 1.7%-2.5%; P < .001) and for biopsy from 24.2% to 29.2% (difference, 5.0%; 95% CI, 3.0%-7.0%; P < .001). CONCLUSIONS AND RELEVANCE Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate. Further studies are needed to assess the relationship to clinical outcomes.read more
Citations
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Journal ArticleDOI
Digital Breast Tomosynthesis: Physics, Artifacts, and Quality Control Considerations
TL;DR: Digital breast tomosynthesis is considered a new imaging modality; therefore, breast imaging facilities are required to obtain a separate certification in addition to that in FFDM, and all personnel are mandated to complete initial DBT training and maintain appropriate continuing medical education credits.
Journal ArticleDOI
Breast Cancer Screening and Prevention
TL;DR: This study estimated that modifiable risk factors (such as postmenopausal obesity, exercise, and alcohol use) account for an additional 40% of cases, and a statistical model, the Breast Cancer Risk Assessment Tool (BRCAT), is the first widely used breast cancer calculator designed for the general population of women.
Journal ArticleDOI
Comparing Diagnostic Performance of Digital Breast Tomosynthesis and Full-Field Digital Mammography in a Hybrid Screening Environment
Catherine S. Giess,Sarvenaz Pourjabbar,Sarvenaz Pourjabbar,Ivan K. Ip,Ronilda Lacson,Emily C. Alper,Ramin Khorasani +6 more
TL;DR: Female patients undergoing screening DBT or FFDM at an academic medical center and outpatient imaging facility between October 2012 and May 2015 were compared to compare the diagnostic performance of screening digital breast tomosynthesis to that of full-field digital mammography in a mixed DBT and FFDM imaging environment.
Proceedings ArticleDOI
Breast cancer detection using synthetic mammograms from generative adversarial networks in convolutional neural networks
Shuyue Guan,Murray H. Loew +1 more
TL;DR: To classify the normal ROIs and abnormal ROIs from DDSM, adding GAN-generated ROIs to the training data can reduce overfitting of the classifier and GAN could be an optional augmentation approach.
Journal ArticleDOI
Digital breast tomosynthesis versus digital mammography: integration of image modalities enhances deep learning-based breast mass classification
TL;DR: Transfer learning facilitates mass classification for both DBT and FFDM, and DBT outperforms FFDM when equipped with transfer learning, and the DBT-based DCNN outperforms the FFDM-basedDCNN when equippedwith transfer learning.
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TL;DR: The overall diagnostic accuracy of digital and film mammography as a means of screening for breast cancer is similar, but digital mammography is more accurate in women under the age of 50 years, women with radiographically dense breasts, and premenopausal or perimenopausal women.
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TL;DR: The USPSTF concludes that the current evidence is insufficient to assess additional benefits and harms of either digital mammography or magnetic resonance imaging instead of film mammography as screening modalities for breast cancer.
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TL;DR: The diagnostic yield, sensitivity, specificity, and diagnostic accuracy (assessed by the area under the receiver operating characteristic curve) of combined mammography plus ultrasound vs mammography alone and the positive predictive value of biopsy recommendations for mammographyplus ultrasound vs Mammography alone are compared.