Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography
Sarah M. Friedewald,Elizabeth A. Rafferty,Stephen L. Rose,Melissa A. Durand,Donna Plecha,Julianne S. Greenberg,Mary Katherine Hayes,Debra S. Copit,Kara L. Carlson,Thomas M. Cink,Lora D. Barke,Linda N. Greer,Dave P. Miller,Emily F. Conant +13 more
TLDR
Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate, and further studies are needed to assess the relationship to clinical outcomes.Abstract:
mammography + tomosynthesis; difference, 1.3 (95% CI, 0.4-2.1; P = .004); for cancer detection, 4.2 (95% CI, 3.8-4.7) with digital mammography vs 5.4 (95% CI, 4.9-6.0) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001); and for invasive cancer detection, 2.9 (95% CI, 2.5-3.2) with digital mammography vs 4.1 (95% CI, 3.7-4.5) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001). The in situ cancer detection rate was 1.4 (95% CI, 1.2-1.6) per 1000 screens with both methods. Adding tomosynthesis was associated with an increase in the positive predictive value for recall from 4.3% to 6.4% (difference, 2.1%; 95% CI, 1.7%-2.5%; P < .001) and for biopsy from 24.2% to 29.2% (difference, 5.0%; 95% CI, 3.0%-7.0%; P < .001). CONCLUSIONS AND RELEVANCE Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate. Further studies are needed to assess the relationship to clinical outcomes.read more
Citations
More filters
Journal ArticleDOI
Breast Cancer Conspicuity on Simultaneously Acquired Digital Mammographic Images versus Digital Breast Tomosynthesis Images
Katrina E. Korhonen,Emily F. Conant,Eric A. Cohen,Marie Synnestvedt,Elizabeth S. McDonald,Susan P. Weinstein +5 more
TL;DR: Cancers were more conspicuous at digital breast tomosynthesis than at digital mammography, and they are more likely to be seen at the craniocaudal view.
Journal ArticleDOI
Implementing Abbreviated MRI Screening Into a Breast Imaging Practice
TL;DR: Steps for implementing abbreviated breast MRI into a breast imaging practice are described to show that MRI performed with an abbreviated protocol for women at average and slightly increased risk depicts mammographically occult biologically significant cancers at early stages.
Journal ArticleDOI
Breast cancer screening: updated recommendations of the Brazilian College of Radiology and Diagnostic Imaging, Brazilian Breast Disease Society, and Brazilian Federation of Gynecological and Obstetrical Associations
Linei A. B. D. Urban,Luciano Fernandes Chala,Selma di Pace Bauab,Marcela Brisighelli Schaefer,Radiá Pereira dos Santos,Norma Medicis de Albuquerque Maranhão,Ana Lucia Kefalas,José Michel Kalaf,Carlos Alberto Pecci Ferreira,Ellyete de Oliveira Canella,João Emílio Peixoto,Heverton Leal Ernesto de Amorim,Hélio Sebastião Amâncio de Camargo Júnior +12 more
TL;DR: The current recommendations for breast cancer screening in Brazil, as devised by the Brazilian College of Radiology and Diagnostic Imaging, the Brazilian Breast Disease Society, and the Brazilian Federation of Gynecological and Obstetrical Associations, are presented.
Journal ArticleDOI
The Potential Impact of Digital Breast Tomosynthesis on the Benign Biopsy Rate in Women Recalled within the UK Breast Screening Programme.
TL;DR: When compared with full-field digital mammography, digital breast tomosynthesis can reduce the benign biopsy rate while maintaining the cancer detection rate.
Journal ArticleDOI
Listening to Women: Expectations and Experiences in Breast Imaging.
TL;DR: This work sought to identify misunderstandings about mammography among women of different racial/ethnic and age groups and identified barriers that keep women from seeking screening mammography and motivators that would propel women toward screening.
References
More filters
Journal ArticleDOI
American Cancer Society Guidelines for Breast Screening with MRI as an Adjunct to Mammography
Debbie Saslow,Carla Boetes,Wylie Burke,Steven E. Harms,Martin O. Leach,Constance D. Lehman,Elizabeth A. Morris,Etta D. Pisano,Mitchell D. Schnall,Stephen F. Sener,Robert A. Smith,Ellen Warner,Martin J. Yaffe,Kimberly S. Andrews,Christy A. Russell +14 more
TL;DR: There are several risk subgroups for which the available data are insufficient to recommend for or against screening, including women with a personal history of breast cancer, carcinoma in situ, atypical hyperplasia, and extremely dense breasts on mammography.
Journal ArticleDOI
Screening for Lung Cancer: U.S. Preventive Services Task Force Recommendation Statement
TL;DR: Although lung cancer screening is not an alternative to smoking cessation, the USPSTF found adequate evidence that annual screening for lung cancer with LDCT in a defined population of high-risk persons can prevent a substantial number of lung cancerrelated deaths.
Journal ArticleDOI
Diagnostic Performance of Digital versus Film Mammography for Breast-Cancer Screening
Etta D. Pisano,Constantine Gatsonis,Edward Hendrick,Martin J. Yaffe,Janet K. Baum,Suddhasatta Acharyya,Emily F. Conant,Laurie L. Fajardo,Lawrence W. Bassett,Roberta A. Jong,Murray Rebner +10 more
TL;DR: The overall diagnostic accuracy of digital and film mammography as a means of screening for breast cancer is similar, but digital mammography is more accurate in women under the age of 50 years, women with radiographically dense breasts, and premenopausal or perimenopausal women.
Journal ArticleDOI
Screening for Breast Cancer: US Preventive Services Task Force Recommendation Statement
Ned Calonge,Diana B. Petitti,Thomas G. DeWitt,Allen J. Dietrich,Kimberly D. Gregory,David C. Grossman,George Isham,Michael L. LeFevre,Rosanne M. Leipzig,Lucy N. Marion,Bernadette Mazurek Melnyk,Virginia A. Moyer,Judith K. Ockene,George F. Sawaya,J. Sanford Schwartz,Timothy J Wilt,US Preventive Serv Task Force +16 more
TL;DR: The USPSTF concludes that the current evidence is insufficient to assess additional benefits and harms of either digital mammography or magnetic resonance imaging instead of film mammography as screening modalities for breast cancer.
Journal ArticleDOI
Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer.
Wendie A. Berg,Jeffrey D. Blume,Jean B. Cormack,Ellen B. Mendelson,Daniel Lehrer,M. Böhm-Vélez,Etta D. Pisano,Roberta A. Jong,W. Phil Evans,Marilyn J. Morton,Mary C. Mahoney,Linda Hovanessian Larsen,Richard G. Barr,Dione M. Farria,Helga S. Marques,Karan Boparai +15 more
TL;DR: The diagnostic yield, sensitivity, specificity, and diagnostic accuracy (assessed by the area under the receiver operating characteristic curve) of combined mammography plus ultrasound vs mammography alone and the positive predictive value of biopsy recommendations for mammographyplus ultrasound vs Mammography alone are compared.