Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography
Sarah M. Friedewald,Elizabeth A. Rafferty,Stephen L. Rose,Melissa A. Durand,Donna Plecha,Julianne S. Greenberg,Mary Katherine Hayes,Debra S. Copit,Kara L. Carlson,Thomas M. Cink,Lora D. Barke,Linda N. Greer,Dave P. Miller,Emily F. Conant +13 more
TLDR
Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate, and further studies are needed to assess the relationship to clinical outcomes.Abstract:
mammography + tomosynthesis; difference, 1.3 (95% CI, 0.4-2.1; P = .004); for cancer detection, 4.2 (95% CI, 3.8-4.7) with digital mammography vs 5.4 (95% CI, 4.9-6.0) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001); and for invasive cancer detection, 2.9 (95% CI, 2.5-3.2) with digital mammography vs 4.1 (95% CI, 3.7-4.5) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001). The in situ cancer detection rate was 1.4 (95% CI, 1.2-1.6) per 1000 screens with both methods. Adding tomosynthesis was associated with an increase in the positive predictive value for recall from 4.3% to 6.4% (difference, 2.1%; 95% CI, 1.7%-2.5%; P < .001) and for biopsy from 24.2% to 29.2% (difference, 5.0%; 95% CI, 3.0%-7.0%; P < .001). CONCLUSIONS AND RELEVANCE Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate. Further studies are needed to assess the relationship to clinical outcomes.read more
Citations
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Multimodality Imaging of Breast Parenchymal Density and Correlation with Risk Assessment
Georg Wengert,Thomas H. Helbich,Doris Leithner,Elizabeth A. Morris,Pascal A. T. Baltzer,Katja Pinker,Katja Pinker +6 more
TL;DR: Standardized breast density assessment using automated volumetric quantitative methods has the potential to be used for risk prediction and stratification and in determining the best screening plan for each woman.
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Mammographic Surveillance After Breast-Conserving Therapy: Impact of Digital Breast Tomosynthesis and Artificial Intelligence-Based Computer-Aided Detection.
TL;DR: In this paper, Gartner Roth discusses this article and discusses the importance of the podcast associated with this article, and recommends one of the following: iTunes, Google Play, or di...
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Mammographic Screening in Older Women: When Is It Time to Stop?
Reni Butler,Liane E. Philpotts +1 more
TL;DR: Observational data support a survival benefit from regular screening in older women with no severe comorbidities, and early studies of digital breast tomosynthesis in Older women suggest that performance metrics are further improved with DBT screening.
Journal ArticleDOI
Characterization of invisible breast cancers in digital mammography and tomosynthesis: radio-pathological correlation.
P. M. Aguilar Angulo,C. Romero Castellano,J. Ruiz Martín,M.P. Sánchez-Camacho González-Carrato,L.M. Cruz Hernández +4 more
TL;DR: In this article, radio-pathologic features of symptomatic breast cancers not detected at digital mammography (DM) and digital breast tomosynthesis (DBT) were reviewed.
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Benefits of digital breast tomosynthesis: A lesion-level analysis.
Tali Amir,Emily B. Ambinder,Susan C. Harvey,Eniola Oluyemi,Mary Kate Jones,Evan L Honig,Matthew D. Alvin,Lisa A. Mullen +7 more
TL;DR: In this article, the authors compare outcome metrics of digital breast tomosynthesis (DBT) breast cancer screening with full-field digital mammogram (FFDM), specifically, to compare recall rates by the type of reca...
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