Breast Cancer Screening Using Tomosynthesis in Combination With Digital Mammography
Sarah M. Friedewald,Elizabeth A. Rafferty,Stephen L. Rose,Melissa A. Durand,Donna Plecha,Julianne S. Greenberg,Mary Katherine Hayes,Debra S. Copit,Kara L. Carlson,Thomas M. Cink,Lora D. Barke,Linda N. Greer,Dave P. Miller,Emily F. Conant +13 more
TLDR
Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate, and further studies are needed to assess the relationship to clinical outcomes.Abstract:
mammography + tomosynthesis; difference, 1.3 (95% CI, 0.4-2.1; P = .004); for cancer detection, 4.2 (95% CI, 3.8-4.7) with digital mammography vs 5.4 (95% CI, 4.9-6.0) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001); and for invasive cancer detection, 2.9 (95% CI, 2.5-3.2) with digital mammography vs 4.1 (95% CI, 3.7-4.5) with digital mammography + tomosynthesis; difference, 1.2 (95% CI, 0.8-1.6; P < .001). The in situ cancer detection rate was 1.4 (95% CI, 1.2-1.6) per 1000 screens with both methods. Adding tomosynthesis was associated with an increase in the positive predictive value for recall from 4.3% to 6.4% (difference, 2.1%; 95% CI, 1.7%-2.5%; P < .001) and for biopsy from 24.2% to 29.2% (difference, 5.0%; 95% CI, 3.0%-7.0%; P < .001). CONCLUSIONS AND RELEVANCE Addition of tomosynthesis to digital mammography was associated with a decrease in recall rate and an increase in cancer detection rate. Further studies are needed to assess the relationship to clinical outcomes.read more
Citations
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Digital breast tomosynthesis at screening assessment: are two views always necessary?
Rabea Haq,Yit Yoong Lim,Anthony J. Maxwell,Emma Hurley,Ursula Beetles,Sara Bundred,Mary E. Wilson,Susan M. Astley,Fiona J. Gilbert +8 more
TL;DR: One-view DBT may not be necessary when used for further assessment of possible screen-detected soft-tissue abnormalities seen only on one FFDM view, and larger studies should be undertaken to investigate this further.
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Detection of noncalcified breast cancer in patients with extremely dense breasts using digital breast tomosynthesis compared with full-field digital mammography.
TL;DR: Addition of DBT to FFDM showed no significant increase in the tumour visibility and diagnostic performance in patients with noncalcified T1 cancer in extremely dense breasts.
Journal ArticleDOI
Progress in diagnosis of breast cancer: Advances in radiology technology.
TL;DR: Use of technological advancements in digital breast tomosynthesis, magnetic resonance imaging, and ultrasound in breast cancer diagnosis will be presented andvantages and disadvantages of these diagnostic interventions when compared to older, traditional X-ray films will be discussed.
Journal ArticleDOI
A randomised trial of screening with digital breast tomosynthesis plus conventional digital 2D mammography versus 2D mammography alone in younger higher risk women.
Anthony J. Maxwell,Michael J Michell,Yit Yoong Lim,Susan M. Astley,Mary E. Wilson,Emma Hurley,D. Gareth Evans,Anthony Howell,Asif Iqbal,John Kotre,Stephen W. Duffy,Julie Morris +11 more
TL;DR: The addition of DBT to 2D mammography in incident screening did not lead to a significant reduction in recall rate, and DBT may increase reader uncertainty until DBT screening experience is acquired.
Journal ArticleDOI
ACR Appropriateness Criteria® Imaging After Mastectomy and Breast Reconstruction.
Samantha L. Heller,Ana Lourenço,Bethany L. Niell,Nicolas Ajkay,Ann L. Brown,Elizabeth H. Dibble,Aarati Didwania,Maxine S. Jochelson,Katherine A. Klein,Tejas S. Mehta,Helen A Pass,Ashley R Stuckey,Mary E Swain,Daymen S Tuscano,Linda Moy +14 more
TL;DR: This review of imaging in the setting of mastectomy with or without reconstruction summarizes the literature and makes recommendations based on available evidence.
References
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TL;DR: The USPSTF concludes that the current evidence is insufficient to assess additional benefits and harms of either digital mammography or magnetic resonance imaging instead of film mammography as screening modalities for breast cancer.
Journal ArticleDOI
Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer.
Wendie A. Berg,Jeffrey D. Blume,Jean B. Cormack,Ellen B. Mendelson,Daniel Lehrer,M. Böhm-Vélez,Etta D. Pisano,Roberta A. Jong,W. Phil Evans,Marilyn J. Morton,Mary C. Mahoney,Linda Hovanessian Larsen,Richard G. Barr,Dione M. Farria,Helga S. Marques,Karan Boparai +15 more
TL;DR: The diagnostic yield, sensitivity, specificity, and diagnostic accuracy (assessed by the area under the receiver operating characteristic curve) of combined mammography plus ultrasound vs mammography alone and the positive predictive value of biopsy recommendations for mammographyplus ultrasound vs Mammography alone are compared.