Journal ArticleDOI
Chemically defined media for commercial fermentations
J. Zhang,Randolph Greasham +1 more
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In this paper, the authors focus on the application, development, and practical considerations of fermentations in chemically defined media in an industrial environment and present a review of the application and process economics of such media.Abstract:
The use of chemically defined media is gaining popularity in some commercial fermentations, particularly for the preparation of biological products. Although these media are still not frequently developed for industrial processes, they do exhibit favorable characteristics at large scale that are not observed with traditional complex media. This review focuses on the application, development, and practical considerations, especially process economics, of fermentations in chemically defined media in an industrial environment.read more
Citations
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Journal ArticleDOI
Development of a Cost-Effective Process for the Heterologous Production of SARS-CoV-2 Spike Receptor Binding Domain Using Pichia pastoris in Stirred-Tank Bioreactor
Diego Gabriel Noseda,Cecilia D'Alessio,Javier Santos,Tommy Idrovo Hidalgo,Florencia Pignataro,Diana E. Wetzler,H. G. Gentili,Alejandro D. Nadra,Ernesto A. Roman,Carlos Humberto Pavan,Lucas Ruberto +10 more
TL;DR: In this article , a method for recombinant RBD production using Pichia pastoris as a cell factory in a stirred-tank bioreactor (SRTB) up to 7 L was developed using a basal saline medium with glycerol, methanol, and compressed air.
Journal ArticleDOI
Mass transfer in aerated culture media combining mixed electrolytes and glucose
TL;DR: The combined effects of mixed electrolyte species and glucose on oxygen transfer were studied in a bubble column with aqueous solutions and the changes in physicochemical properties were highly collinear with composition variables.
Book ChapterDOI
Bio-fermentative Production of Xanthan Gum Biopolymer and Its Application in Petroleum Sector
Nanthakumar Kuppanan,Paul Jeyaseelan,Shishram Chahar,Subhasis Das,Veeranna A. Channashettar,Banwari Lal +5 more
TL;DR: The xanthan gum is a natural microbial polysaccharide known as gums or exopolysaccharides (EPS) which has excellent characteristics such as gel formation, thickening, emulsion stabilizing effect, salt tolerance, pH resistance and stability to various enzymes makes this product industrially an important additive.
References
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Journal ArticleDOI
The design of optimum multifactorial experiments
R. L. Plackett,J. P. Burman +1 more
Journal ArticleDOI
Sequential Application of Simplex Designs in Optimisation and Evolutionary Operation
TL;DR: A technique for empirical optimisation is presented in which a sequence of experimental designs each in the form of a regular or irregular simplex is used, each simplex having all vertices but one in common with the preceding simplex, and being completed by one new point.
Journal ArticleDOI
A novel progressive spongiform encephalopathy in cattle.
G. A. H. Wells,A.C. Scott,C.T. Johnson,R.F. Gunning,R. D. Hancock,Martin Jeffrey,M. Dawson,R. Bradley +7 more
Book
Manual of industrial microbiology and biotechnology
Arnold L. Demain,Julian Davies +1 more
TL;DR: The culture The process Strain Improvement Immobilization and Cell Culture Biochemical Engineering Special Topics as discussed by the authors The culture the process strain improvement Immobilisation and cell culture Biochemical engineering
Journal ArticleDOI
Growth characteristics of group A streptococci in a new chemically defined medium.
I van de Rijn,R E Kessler +1 more
TL;DR: A new chemically defined medium for the growth of group A streptococci has been formulated and the production of virulence factors and extracellular enzymes during growth in this new medium was comparable to that in complex media.
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