Journal ArticleDOI
Chemically defined media for commercial fermentations
J. Zhang,Randolph Greasham +1 more
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TLDR
In this paper, the authors focus on the application, development, and practical considerations of fermentations in chemically defined media in an industrial environment and present a review of the application and process economics of such media.Abstract:
The use of chemically defined media is gaining popularity in some commercial fermentations, particularly for the preparation of biological products. Although these media are still not frequently developed for industrial processes, they do exhibit favorable characteristics at large scale that are not observed with traditional complex media. This review focuses on the application, development, and practical considerations, especially process economics, of fermentations in chemically defined media in an industrial environment.read more
Citations
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Journal ArticleDOI
Hydrolysates from Atlantic cod (Gadus morhua L.) viscera as components of microbial growth media
TL;DR: Three hydrolysates made from cod viscera by different enzymatic hydrolysis procedures were tested as a combined source for nitrogen, amino acids and vitamins in microbial growth media and the generally best enzyme for production of a fish peptone from cod Viscera was found to be Alcalase.
Journal ArticleDOI
Microbial fertilizers: A comprehensive review of current findings and future perspectives
TL;DR: In this article, a review of the importance of microbial fertilizers and their beneficial effects on the plants, as well as a brief survey of the different aspects of production processes with a special emphasis on mass multiplication is presented.
Journal ArticleDOI
Bioprocess engineering issues that would be faced in producing a DNA vaccine at up to 100 m3 fermentation scale for an influenza pandemic.
Mike Hoare,M. Susana Levy,Daniel G. Bracewell,Steven D. Doig,Simyee Kong,Nigel J. Titchener-Hooker,John M. Ward,Peter Dunnill +7 more
TL;DR: This approach addresses the uncertainty of timing of a pandemic that precludes purpose‐built facilities and concludes that such processing would be challenging but feasible.
Book ChapterDOI
Media for industrial fermentations
TL;DR: This chapter commences by examining the general requirements of fermentation media composition and formulation, and the specialized requirements of media for animal cell culture are discussed.
Journal ArticleDOI
Development of chemically defined medium for Mannheimia succiniciproducens based on its genome sequence
Hyohak Song,Tae Yong Kim,Bo-Kyeong Choi,Seong Jun Choi,Lars K. Nielsen,Ho Nam Chang,Sang Yup Lee +6 more
TL;DR: A novel methodology for the development of a chemically defined medium (CDM) using genome-scale metabolic network and flux balance analysis and an optimal CDM for the enhancement of cell growth and succinic acid production was formulated with a single-addition technique.
References
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Journal ArticleDOI
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R. L. Plackett,J. P. Burman +1 more
Journal ArticleDOI
Sequential Application of Simplex Designs in Optimisation and Evolutionary Operation
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Journal ArticleDOI
Growth characteristics of group A streptococci in a new chemically defined medium.
I van de Rijn,R E Kessler +1 more
TL;DR: A new chemically defined medium for the growth of group A streptococci has been formulated and the production of virulence factors and extracellular enzymes during growth in this new medium was comparable to that in complex media.
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