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Journal ArticleDOI

Chemically defined media for commercial fermentations

J. Zhang, +1 more
- 23 Apr 1999 - 
- Vol. 51, Iss: 4, pp 407-421
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TLDR
In this paper, the authors focus on the application, development, and practical considerations of fermentations in chemically defined media in an industrial environment and present a review of the application and process economics of such media.
Abstract
The use of chemically defined media is gaining popularity in some commercial fermentations, particularly for the preparation of biological products. Although these media are still not frequently developed for industrial processes, they do exhibit favorable characteristics at large scale that are not observed with traditional complex media. This review focuses on the application, development, and practical considerations, especially process economics, of fermentations in chemically defined media in an industrial environment.

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Citations
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Journal ArticleDOI

Re-engineering Escherichia coli for ethanol production.

TL;DR: A lactate producing derivative of Escherichia coli KO11, strain SZ110, was re-engineered for ethanol production by deleting genes encoding all fermentative routes for NADH and randomly inserting a promoterless mini-Tn5 cassette (transpososome) containing the complete Zymomonas mobilis ethanol pathway into the chromosome.
Journal ArticleDOI

Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli.

TL;DR: The use of lignocellulose as a source of sugars for bioproducts requires the development of biocatalysts that maximize product yields by fermenting mixtures of hexose and pentose sugars to completion.
Journal ArticleDOI

Development of chemically defined media supporting high-cell-density growth of lactococci, enterococci, and streptococci.

TL;DR: The new chemically defined media developed in this study support high-cell-density growth of numerous strains of L. lactis, Enterococcus faecalis, and Streptococcus thermophilus.
Journal ArticleDOI

Biosynthesis of silver nanoparticle by endophytic fungi Pencillium sp. isolated from Curcuma longa (turmeric) and its antibacterial activity against pathogenic gram negative bacteria

TL;DR: The AgNPs produced by endophytic fungi displayed considerable antibacterial activity and hence this study would prove to provide novel antimicrobial agents synthesized in a facile way.
References
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Journal ArticleDOI

The design of optimum multifactorial experiments

R. L. Plackett, +1 more
- 01 Jun 1946 - 
Journal ArticleDOI

Sequential Application of Simplex Designs in Optimisation and Evolutionary Operation

TL;DR: A technique for empirical optimisation is presented in which a sequence of experimental designs each in the form of a regular or irregular simplex is used, each simplex having all vertices but one in common with the preceding simplex, and being completed by one new point.
Book

Manual of industrial microbiology and biotechnology

TL;DR: The culture The process Strain Improvement Immobilization and Cell Culture Biochemical Engineering Special Topics as discussed by the authors The culture the process strain improvement Immobilisation and cell culture Biochemical engineering
Journal ArticleDOI

Growth characteristics of group A streptococci in a new chemically defined medium.

TL;DR: A new chemically defined medium for the growth of group A streptococci has been formulated and the production of virulence factors and extracellular enzymes during growth in this new medium was comparable to that in complex media.
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