Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
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TLDR
The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2020-05-01 and is currently open access. It has received 7787 citations till now. The article focuses on the topics: Pneumonia & ARDS.read more
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Systematic review and meta-analysis of predictive symptoms and comorbidities for severe COVID-19 infection
Vageesh Jain,Jin-Min Yuan +1 more
TL;DR: Dyspnoea was the only symptom strongly predictive for both severe disease and ICU admission, and could be useful in guiding clinical management decisions early in the course of illness.
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Emergence and spread of a SARS-CoV-2 lineage A variant (A.23.1) with altered spike protein in Uganda.
Daniel Lule Bugembe,My V. T. Phan,Isaac Ssewanyana,Patrick Semanda,Hellen Nansumba,Beatrice Dhaala,Susan Nabadda,Áine O'Toole,Andrew Rambaut,Pontiano Kaleebu,Pontiano Kaleebu,Matthew Cotten,Matthew Cotten +12 more
TL;DR: The A.23.1 spike-protein-coding region has changes similar to VOCs including a change at position 613, a change in the furin cleavage site that extends the basic amino acid motif and multiple changes in the immunogenic N-terminal domain this paper.
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Robust and optimal predictive control of the COVID-19 outbreak
TL;DR: The theoretical findings support various recent studies by showing that adaptive feedback strategies are required to reliably contain the COVID-19 outbreak, and well-designed policies can significantly reduce the number of fatalities compared to simpler policies while keeping the amount of social distancing measures on the same level.
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Clinical features, diagnostics, and outcomes of patients presenting with acute respiratory illness: A retrospective cohort study of patients with and without COVID-19.
Sachin J. Shah,Peter N Barish,Priya A. Prasad,Amy Kistler,Norma Neff,Jack Kamm,Lucy M Li,Charles Y. Chiu,Jennifer M. Babik,Margaret C. Fang,Yumiko Abe-Jones,Narges Alipanah,Francisco N Alvarez,Olga Borisovna Botvinnik,Gloria Castaneda,Rand Dadasovich,Jennifer Davis,Xianding Deng,Joseph L. DeRisi,Angela M. Detweiler,Scot Federman,John R. Haliburton,Samantha Hao,Andrew D. Kerkhoff,G. Renuka Kumar,Katherine Malcolm,Sabrina A Mann,Sandra P Martinez,Rupa K Mary,Eran Mick,Lusajo L. Mwakibete,Nader Najafi,Michael J. Peluso,Maira Phelps,Angela Oliveira Pisco,Kalani Ratnasiri,Luis Rubio,Anna B Sellas,Kyla D Sherwood,Jonathan Sheu,Natasha Spottiswoode,Michelle Tan,Guixia Yu,Kirsten N. Kangelaris,Charles Langelier +44 more
TL;DR: Patients with COVID-19 were more likely to be admitted to the hospital, have longer hospitalizations and develop ARDS, and were unlikely to have co-existent viral infections.
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Tocilizumab for treatment patients with COVID-19: Recommended medication for novel disease.
TL;DR: Based on evidence of the Tocilizumab’s effect on the SARS COV 2, researchers hope this drug will make effective and promising treatment to improve lung tissue inflammation in patients with the fatal COVID-19 virus.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
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