Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
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TLDR
The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2020-05-01 and is currently open access. It has received 7787 citations till now. The article focuses on the topics: Pneumonia & ARDS.read more
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Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study.
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Wang et al. as discussed by the authors used univariable and multivariable logistic regression methods to explore the risk factors associated with in-hospital death, including older age, high SOFA score and d-dimer greater than 1 μg/mL.
Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
Fei Zhou,Ting Yu,Ronghui Du,Guohui Fan,Ying Liu,Zhibo Liu,Jie Xiang,Yeming Wang,Bin Song,Xiaoying Gu,Xiaoying Gu,Lulu Guan,Yuan Wei,Li Hui,Xudong Wu,Jiuyang Xu,Shengjin Tu,Yi Zhang,Hua Chen,Bin Cao +19 more
TL;DR: Prolonged viral shedding provides the rationale for a strategy of isolation of infected patients and optimal antiviral interventions in the future.
Journal ArticleDOI
Baseline Characteristics and Outcomes of 1591 Patients Infected With SARS-CoV-2 Admitted to ICUs of the Lombardy Region, Italy.
Giacomo Grasselli,Giacomo Grasselli,Alberto Zangrillo,Alberto Zanella,Alberto Zanella,Massimo Antonelli,Massimo Antonelli,Luca Cabrini,Antonio Castelli,Danilo Cereda,Antonio Coluccello,Giuseppe Foti,Roberto Fumagalli,Giorgio Antonio Iotti,Nicola Latronico,Luca Lorini,Stefano Merler,Giuseppe Natalini,Alessandra Piatti,Marco Ranieri,Anna Mara Scandroglio,Enrico Storti,Maurizio Cecconi,Antonio Pesenti,Antonio Pesenti +24 more
TL;DR: Patients with coronavirus disease 2019 (COVID-19) requiring treatment in an intensive care unit (ICU) in the Lombardy region of Italy were characterized, including data on clinical management, respiratory failure, and patient mortality.
Journal ArticleDOI
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review.
W. Joost Wiersinga,Andrew Rhodes,Allen C. Cheng,Sharon J. Peacock,Sharon J. Peacock,Hallie C. Prescott +5 more
TL;DR: This review discusses current evidence regarding the pathophysiology, transmission, diagnosis, and management of COVID-19, the novel severe acute respiratory syndrome coronavirus 2 pandemic that has caused a worldwide sudden and substantial increase in hospitalizations for pneumonia with multiorgan disease.
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The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status.
Yan Rong Guo,Qing Dong Cao,Zhong Si Hong,Yuan Yang Tan,Shoudeng Chen,Hong Jun Jin,Kai Sen Tan,De Yun Wang,Yan Yan +8 more
TL;DR: The latest research progress of the epidemiology, pathogenesis, and clinical characteristics of COVID-19 are summarized, and the current treatment and scientific advancements to combat the epidemic novel coronavirus are discussed.
References
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Short-term outcome of critically ill patients with severe acute respiratory syndrome.
Charles D. Gomersall,Gavin M. Joynt,Philip T H Lam,Thomas S.T. Li,Florence H. Y. Yap,Doris T. C. Lam,T. A. Buckley,Joseph J.Y. Sung,David S.C. Hui,Gregory E. Antonio,Anil T. Ahuja,Patricia Leung +11 more
TL;DR: Increased age, severity of illness, lymphocyte count, decreased steroid dose, positive fluid balance, chronic disease or immunosuppression and nosocomial sepsis were associated with poor outcome on univariate analysis.
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Practice of diagnosis and management of acute respiratory distress syndrome in mainland China: a cross-sectional study.
Ling Liu,Yi Yang,Zhiwei Gao,Zhiwei Gao,Maoqin Li,Xinwei Mu,Xiaochun Ma,Guicheng Li,Wen Sun,Xue Wang,Qin Gu,Ruiqiang Zheng,Hongsheng Zhao,Dan Ao,Wenkui Yu,Yushan Wang,Kang Chen,Jie Yan,Jianguo Li,Guolong Cai,Yurong Wang,Hongliang Wang,Yan Kang,Arthur S. Slutsky,Songqiao Liu,Jianfen Xie,Haibo Qiu +26 more
TL;DR: Despite general acceptance of low Vt and limited Pplat, high driving pressure, low PEEP and low use of adjunctive measures may still be a concern in mainland China, especially in patients with severe ARDS.
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Wuhan: Britons to be evacuated as scientists estimate 44 000 cases of 2019-nCOV in the city.
TL;DR: The UK government has announced plans to fly hundreds of British citizens back from Wuhan, the epicentre of the 2019-nCOV outbreak, and to quarantine them for two weeks, and other countries have also started to repatriate citizens.
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The International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) response to the Zika virus outbreak
Olaa Mohamed-Ahmed,Bethan McDonald,Raul Pardinaz-Solis,Louise Sigfrid,Chelsea McMullen,Sarah Moore,Kajsa-Stina Longuere,Maria del Pilar Ramon-Pardo,Nikki Shindo,Gail Carson +9 more
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