Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
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TLDR
The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2020-05-01 and is currently open access. It has received 7787 citations till now. The article focuses on the topics: Pneumonia & ARDS.read more
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Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients.
Anna C. Aschenbrenner,Maria Mouktaroudi,Benjamin Krämer,Marie Oestreich,Nikolaos Antonakos,Melanie Nuesch-Germano,Konstantina Gkizeli,Lorenzo Bonaguro,Nico Reusch,Kevin Baßler,Maria Saridaki,Rainer Knoll,Tal Pecht,Theodore S. Kapellos,Sarandia Doulou,Charlotte Kröger,Miriam Herbert,Lisa Holsten,Arik Horne,Ioanna D. Gemünd,Nikoletta Rovina,Shobhit Agrawal,Kilian Dahm,Martina van Uelft,Anna Drews,Lena Lenkeit,Niklas Bruse,Jelle Gerretsen,Jannik Gierlich,Matthias Becker,Kristian Händler,Michael Kraut,Heidi Theis,Simachew Mengiste,Elena De Domenico,Jonas Schulte-Schrepping,Lea Seep,Jan Raabe,Christoph Hoffmeister,Michael ToVinh,Verena Keitel,Gereon Rieke,Valentina Talevi,Dirk Skowasch,N. Ahmad Aziz,N. Ahmad Aziz,Peter Pickkers,Frank L. van de Veerdonk,Mihai G. Netea,Mihai G. Netea,Joachim L. Schultze,Joachim L. Schultze,Matthijs Kox,Monique M.B. Breteler,Monique M.B. Breteler,Jacob Nattermann,Antonia Koutsoukou,Evangelos J. Giamarellos-Bourboulis,Thomas Ulas +58 more
TL;DR: This article performed RNA-seq of whole blood cell transcriptomes and granulocyte preparations from mild and severe COVID-19 patients and analyzed the data using a combination of conventional and data-driven co-expression analysis.
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Acute kidney injury in SARS-CoV-2 infected patients.
Vito Fanelli,Marco Fiorentino,Vincenzo Cantaluppi,Loreto Gesualdo,Giovanni Stallone,Claudio Ronco,Giuseppe Castellano +6 more
TL;DR: Possible mechanisms of the COVID-19-induced AKI are discussed, indicating potential new approaches for risk stratification of SARS-CoV-2 infected patients that may help clinical decision in this emerging scenario.
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First cases of COVID-19 in heart transplantation from China.
Fei Li,Jie Cai,Nianguo Dong +2 more
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Gastrointestinal and liver manifestations in patients with COVID-19.
TL;DR: In this article, the authors summarized the recent studies reporting of gastrointestinal and liver manifestations during the course of COVID-19, including anorexia, nausea, vomiting, and diarrhea, and in some cases digestive symptoms may occur in the absence of any respiratory symptoms.
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Acute complications and mortality in hospitalized patients with coronavirus disease 2019: a systematic review and meta-analysis.
Nicola Potere,Emanuele Valeriani,Matteo Candeloro,Marco Tana,Ettore Porreca,Antonio Abbate,Silvia Spoto,Anne W S Rutjes,Marcello Di Nisio +8 more
TL;DR: Mortality was very high in critically ill patients based on very low-quality evidence due to striking heterogeneity and risk of bias, although reported by only one third of the studies suggesting considerable underreporting.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
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TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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TL;DR: The guidelines focused on 4 key domains: (1) AKI definition, (2) prevention and treatment of AKI, (3) contrastinduced AKI (CI-AKI) and (4) dialysis interventions for the treatment ofAKI.
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