Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
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TLDR
The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2020-05-01 and is currently open access. It has received 7787 citations till now. The article focuses on the topics: Pneumonia & ARDS.read more
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Neutrophil-to-lymphocyte ratio as an independent risk factor for mortality in hospitalized patients with COVID-19.
Yuwei Liu,Xuebei Du,Jing Chen,Yalei Jin,Li Peng,Harry H.X. Wang,Harry H.X. Wang,Harry H.X. Wang,Mingqi Luo,Ling Chen,Yan Zhao +10 more
TL;DR: NLR is an independent risk factor of the in-hospital mortality for COVID-19 patients especially for male, and assessment of NLR may help identify high risk individuals with CO VID-19.
Journal ArticleDOI
Risk factors for severe and critically ill COVID-19 patients: A review.
Ya-dong Gao,Mei Ding,Mei Ding,Xiang Dong,Jin-jin Zhang,Ahmet Kursat Azkur,Dilek Azkur,Hui Gan,Yuan-Li Sun,Wei Fu,Wei Li,Hui-ling Liang,Yiyuan Cao,Qi Yan,Can Cao,Hong-yu Gao,Marie-Charlotte Brüggen,Willem van de Veen,Milena Sokolowska,Mübeccel Akdis,Cezmi A. Akdis +20 more
TL;DR: In this review, the scientific evidence on the risk factors of severity of COVID‐19 are highlighted and socioeconomic status, diet, lifestyle, geographical differences, ethnicity, exposed viral load, day of initiation of treatment, and quality of health care have been reported to influence individual outcomes.
Journal ArticleDOI
Detectable Serum Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load (RNAemia) Is Closely Correlated With Drastically Elevated Interleukin 6 Level in Critically Ill Patients With Coronavirus Disease 2019.
Xiaohua Chen,Binghong Zhao,Yueming Qu,Yueming Qu,Yurou Chen,Jie Xiong,Yong Feng,Dong Men,Qianchuan Huang,Ying Liu,Bo Yang,Jinya Ding,Feng Li +12 more
TL;DR: Detectable serum SARS-Cov-2 RNA(RNAaemia) in COVID-19 patients was associated with elevated IL-6 concentration and poor prognosis, andIL-6 could be a potential therapeutic target for critically ill patients with an excessive inflammatory response.
Journal ArticleDOI
Angiotensin?converting enzyme 2 (ACE2), SARS?CoV?2 and the pathophysiology of coronavirus disease 2019 (COVID?19)
Arno R. Bourgonje,Amaal Eman Abdulle,Wim Timens,Jan-Luuk Hillebrands,Gerjan Navis,Sanne J. Gordijn,Marieke C. Bolling,Gerard Dijkstra,Adriaan A. Voors,Albert D. M. E. Osterhaus,Peter H. J. van der Voort,Douwe J. Mulder,Harry van Goor +12 more
TL;DR: The role of ACE2 in CO VID‐19 pathophysiology is described, including factors influencing ACE2 expression and activity in relation to COVID‐19 severity, and the relevant pathological changes resulting from SARS‐CoV‐2 infection are discussed.
Journal ArticleDOI
Review article: Gastrointestinal features in COVID-19 and the possibility of faecal transmission
TL;DR: There is little published evidence on the gastrointestinal features of COVID‐19 and its use in clinical practice.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
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TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
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