Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.
Xiaobo Yang,Yuan Yu,Jiqian Xu,Huaqing Shu,Jia'an Xia,Hong Liu,Hong Liu,Yongran Wu,Lu Zhang,Zhui Yu,Minghao Fang,Ting Yu,Yaxin Wang,Shangwen Pan,Xiaojing Zou,Shiying Yuan,You Shang,You Shang +17 more
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TLDR
The clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia who were admitted to the intensive care unit (ICU) of Wuhan Jin Yin-tan hospital between late December, 2019 and Jan 26, 2020 are described.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2020-05-01 and is currently open access. It has received 7787 citations till now. The article focuses on the topics: Pneumonia & ARDS.read more
Citations
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Extracorporeal Membrane Oxygenation Support in Severe COVID-19.
Zachary N. Kon,Deane E. Smith,Stephanie H. Chang,Ronald Goldenberg,Luis F. Angel,Julius A. Carillo,Travis C. Geraci,Robert J. Cerfolio,Robert A. Montgomery,Nader Moazami,Aubrey C. Galloway +10 more
TL;DR: The early outcomes presented here suggest that the judicious use of ECMO support in severe Covid-19 may be clinically beneficial.
Journal ArticleDOI
Immunological co-ordination between gut and lungs in SARS-CoV-2 infection.
TL;DR: The immunological co-ordination between gut and lungs that facilitates SARS-CoV-2 to infect and multiply in the inflammatory bowel disease (IBD) and non-IBD patients is discussed.
Journal ArticleDOI
Abnormal liver function tests predict transfer to intensive care unit and death in COVID-19.
Salvatore Piano,Andrea Dalbeni,E. Vettore,Devis Benfaremo,Massimo Mattioli,Carmine Gambino,Viviana Framba,Lorenzo Cerruti,A. Mantovani,Andrea Martini,Michele Maria Luchetti,Roberto M. Serra,Anna Maria Cattelan,Roberto Vettor,Paolo Angeli +14 more
TL;DR: The aim of this study was to assess the prevalence, the characteristics and the clinical impact of abnormal LFTs in hospitalized, non‐critically ill patients with COVID‐19.
Journal ArticleDOI
Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19.
Francisco J. Salguero,Andrew White,Gillian S. Slack,Susan A. Fotheringham,Kevin R. Bewley,Karen E. Gooch,Stephanie Longet,Holly E. Humphries,Robert J. Watson,Laura Hunter,Kathryn A. Ryan,Yper Hall,Laura Sibley,Charlotte Sarfas,Lauren Allen,Marilyn Aram,Emily Brunt,Phillip Brown,Karen R. Buttigieg,Breeze E. Cavell,Rebecca Cobb,Naomi Coombes,Alistair C. Darby,Owen Daykin-Pont,Michael J. Elmore,Isabel García-Dorival,Konstantinos Gkolfinos,Kerry J Godwin,Jade Gouriet,Rachel Halkerston,Debbie J Harris,Thomas Hender,Catherine M K Ho,Chelsea L Kennard,Daniel Knott,Stephanie Leung,Vanessa Lucas,Adam Mabbutt,Alexandra L. Morrison,Charlotte Nelson,Didier Ngabo,Jemma Paterson,Elizabeth J Penn,Steve Pullan,Irene Taylor,Tom Tipton,Stephen Thomas,Julia A. Tree,Carrie Turner,Edith Vamos,Nadina Wand,Nathan R Wiblin,Sue Charlton,Xiaofeng Dong,Bassam Hallis,Geoffrey Pearson,Emma Rayner,Andrew G. Nicholson,Simon G. P. Funnell,Julian A. Hiscox,Julian A. Hiscox,Mike Dennis,Fergus V. Gleeson,Sally Sharpe,Miles W. Carroll +64 more
TL;DR: It is shown that SARS-CoV-2 replicates in the upper and lower respiratory tract and causes pulmonary lesions in both rhesus and cynomolgus macaques, resembling the mild clinical cases of COVID-19 in humans.
Journal ArticleDOI
COVID-19-associated fungal infections
Martin Hoenigl,Danila Seidel,Rosanne Sprute,Cristina Cunha,Matteo Oliverio,Gustavo H. Goldman,Ashraf S. Ibrahim,Agostinho Carvalho +7 more
TL;DR: In this article , the authors reviewed the incidence of COVID-19-associated invasive fungal infections caused by these fungi in low-, middle- and high-income countries, evaluating the epidemiology, clinical risk factors, predisposing features of the host environment and immunological mechanisms that underlie the pathogenesis of these co-infections, set the scene for future research and development of clinical guidance.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
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TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
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