Cryptic genetic variation: evolution's hidden substrate
TLDR
The empirical support for widespread CGV in natural populations is reviewed, including its potential role in emerging human diseases and the growing evidence of its contribution to evolution are reviewed.Citations
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Host genotype and age shape the leaf and root microbiomes of a wild perennial plant
Maggie R. Wagner,Derek S. Lundberg,Tijana Glavina del Rio,Susannah G. Tringe,Jeffery L. Dangl,Thomas Mitchell-Olds +5 more
TL;DR: This large-scale field experiment disentangle the effects of genotype, environment, age and year of harvest on bacterial communities associated with leaves and roots of Boechera stricta (Brassicaceae), a perennial wild mustard to demonstrate how genotype-by-environment interactions contribute to the complexity of microbiome assembly in natural environments.
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Major Impacts of Widespread Structural Variation on Gene Expression and Crop Improvement in Tomato.
Michael Alonge,Xingang Wang,Matthias Benoit,Matthias Benoit,Sebastian Soyk,Lara Pereira,Lei Zhang,Hamsini Suresh,Srividya Ramakrishnan,Florian Maumus,Danielle Ciren,Yuval Levy,Tom Hai Harel,Gili Shalev-Schlosser,Ziva Amsellem,Hamid Razifard,Ana L. Caicedo,Denise M. Tieman,Harry J. Klee,Melanie Kirsche,Sergey Aganezov,T. Rhyker Ranallo-Benavidez,Zachary H. Lemmon,Jennifer Kim,Jennifer Kim,Gina Robitaille,Gina Robitaille,Melissa Kramer,Sara Goodwin,W. Richard McCombie,Samuel F. Hutton,Joyce Van Eck,Joyce Van Eck,Jesse Gillis,Yuval Eshed,Fritz J. Sedlazeck,Esther van der Knaap,Michael C. Schatz,Michael C. Schatz,Zachary B. Lippman,Zachary B. Lippman +40 more
TL;DR: This panSV genome, along with 14 new reference assemblies, revealed large-scale intermixing of diverse genotypes, as well as thousands of SVs intersecting genes and cis-regulatory regions, and showed how multiple SVs that changed gene dosage and expression levels modified fruit flavor, size, and production.
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Evaluating 'Plasticity-First' Evolution in Nature: Key Criteria and Empirical Approaches
TL;DR: The goal is to provide a means by which the role of plasticity in adaptive evolution can be assessed and present much-needed key criteria to allow tests in diverse, natural systems.
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Beyond buying time: The role of plasticity in phenotypic adaptation to rapid environmental change
TL;DR: The need for cross-disciplinary collaborations is advocated to settle the question of whether plasticity will promote or retard species' rates of adaptation to ever-more stressful environmental conditions.
References
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National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
Mariel M. Finucane,Gretchen A Stevens,Melanie J. Cowan,Goodarz Danaei,John K Lin,Christopher J. Paciorek,Gitanjali M Singh,Hialy R. Gutierrez,Yuan Lu,Adil N. Bahalim,Farshad Farzadfar,Leanne M Riley,Majid Ezzati +12 more
TL;DR: In this paper, the authors estimated trends and their uncertainties of mean BMI for adults 20 years and older in 199 countries and territories, and used a Bayesian hierarchical model to estimate mean BMI by age, country, and year.
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Selected major risk factors and global and regional burden of disease
TL;DR: Substantial proportions of global disease burden are attributable to these major risks, to an extent greater than previously estimated.