Journal ArticleDOI
Effect of Surface Properties on Nanoparticle–Cell Interactions
Ayush Verma,Francesco Stellacci +1 more
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TLDR
An understanding of how synthetic and natural chemical moieties on the nanoparticle surface (in addition to nanoparticle shape and size) impact their interaction with lipid bilayers and cells is presented.Abstract:
The interaction of nanomaterials with cells and lipid bilayers is critical in many applications such as phototherapy, imaging, and drug/gene delivery. These applications require a firm control over nanoparticle-cell interactions, which are mainly dictated by surface properties of nanoparticles. This critical Review presents an understanding of how synthetic and natural chemical moieties on the nanoparticle surface (in addition to nanoparticle shape and size) impact their interaction with lipid bilayers and cells. Challenges for undertaking a systematic study to elucidate nanoparticle-cell interactions are also discussed.read more
Citations
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Nanomaterial exposure, toxicity, and impact on human health
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Syntheses and biomedical applications of hollow micro-/nano-spheres with large-through-holes
Yinsong Si,Min Chen,Limin Wu +2 more
TL;DR: This review provides a comprehensive overview of synthesis methods of HMLS obtained from the template-directed approach, shell-breaking method, Ostwald ripening and galvanic replacement primarily based on the formation mechanism of the large-through-holes in the shell.
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Assessing iron oxide nanoparticle toxicity in vitro: current status and future prospects
TL;DR: An overview is presented of different types of nanomaterials, focusing mostly on iron oxide nanoparticles, developed for biomedical research, and several key parameters are highlighted and novel methods suggested, emphasizing the importance of intracellular nanoparticle degradation and linking toxicity data to functional nanoparticle levels, which could help to advance any progress in this highly important research topic.
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Magnetic targeting of surface-modified superparamagnetic iron oxide nanoparticles yields antibacterial efficacy against biofilms of gentamicin-resistant staphylococci
Guruprakash Subbiahdoss,Shahriar Sharifi,Dirk W. Grijpma,Dirk W. Grijpma,Sophie Laurent,Henny C. van der Mei,Morteza Mahmoudi,Morteza Mahmoudi,Henk J. Busscher +8 more
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Monodispersity control in the synthesis of monometallic and bimetallic quasi-spherical gold and silver nanoparticles.
TL;DR: A variety of colloidal synthesis methods in use today for the preparation of monodisperse Au, Ag, and bimetallic Au-Ag nanoparticles are described, with the emphasis on the analysis of the efficacy of each method for tailoring the nanoparticle size and crystal structure.
References
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Biodegradable nanoparticles for drug and gene delivery to cells and tissue
Jayanth Panyam,Vinod Labhasetwar +1 more
TL;DR: Based on the above mechanism, various potential applications of nanoparticles for delivery of therapeutic agents to the cells and tissue are discussed.