Journal ArticleDOI
European experts consensus statement on cystic tumours of the pancreas.
Marco Del Chiaro,Caroline S. Verbeke,Roberto Salvia,Günter Klöppel,Jens Werner,Colin J. McKay,Helmut Friess,Riccardo Manfredi,Eric Van Cutsem,Matthias Löhr,Ralf Segersvärd,L. Abakken,Mustapha Adham,N. Albin,Å. Andrén-Sandberg,Urban Arnelo,Marco J. Bruno,Djuna L. Cahen,Carla Cappelli,Guido Costamagna,M Del Chiaro,G. Delle Fave,Irene Esposito,Massimo Falconi,Helmut Friess,Paula Ghaneh,I. P. Gladhaug,Stephan L. Haas,Truls Hauge,Jakob R. Izbicki,Günther Klöppel,Markus M. Lerch,Lars Lundell,Jutta Lüttges,M. Löhr,R. Manfredi,Julia Mayerle,C. McKay,Kofi Oppong,Aldis Pukitis,Elena Rangelova,Thomas Rösch,Roberto Salvia,Richard D. Schulick,R. Segersvärd,T. Sufferlein,E. Van Cutsem,S. van der Merwe,C. Verbeke,J. Werner,Giuseppe Zamboni +50 more
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TLDR
Diagnostic computerized tomography and/or magnetic resonance imaging are indicated in all patients with cystic lesion of the pancreas and in lesions with a suspicion of malignancy, otherwise organ preserving procedures may be considered.About:
This article is published in Digestive and Liver Disease.The article was published on 2013-09-01. It has received 411 citations till now. The article focuses on the topics: Intraductal papillary mucinous neoplasm & Cystic Neoplasm.read more
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Journal ArticleDOI
Revisions of international consensus Fukuoka guidelines for the management of IPMN of the pancreas.
Masao Tanaka,Carlos Fernandez-del Castillo,Terumi Kamisawa,Jin-Young Jang,Philippe Lévy,Takao Ohtsuka,Roberto Salvia,Yasuhiro Shimizu,Minoru Tada,Christopher L. Wolfgang +9 more
TL;DR: The working group has revised the guidelines regarding prediction of invasive carcinoma and high-grade dysplasia, surveillance, and postoperative follow-up of IPMN and includes updated information and recommendations based on the current understanding.
Journal ArticleDOI
European evidence-based guidelines on pancreatic cystic neoplasms
Marco Del Chiaro,Marc G. Besselink,Lianne Scholten,Marco J. Bruno,Djuna L. Cahen,Thomas M. Gress,Jeanin E. van Hooft,Markus M. Lerch,Julia Mayerle,Thilo Hackert,Sohei Satoi,Alessandro Zerbi,David Cunningham,Claudio De Angelis,Marc Giovanni,Enrique de-Madaria,Péter Hegyi,Jonas Rosendahl,Helmut Friess,Riccardo Manfredi,Philippe Lévy,Francisco X. Real,Alain Sauvanet,Mohammed Abu Hilal,Giovanni Marchegiani,Irene Esposito,Paula Ghaneh,Marc R. W. Engelbrecht,Paul Fockens,Nadine C.M. van Huijgevoort,Christopher L. Wolfgang,Claudio Bassi,Natalya Gubergrits,Caroline S. Verbeke,Günter Klöppel,Aldo Scarpa,Giuseppe Zamboni,Anne Marie Lennon,Malin Sund,Nikolaos Kartalis,Lars Grenacher,Massimo Falconi,Urban Arnelo,Kostantin V. Kopchak,Kofi Oppong,Colin J. McKay,Truls Hauge,Kevin C. Conlon,Mustapha Adham,Güralp O. Ceyhan,Roberto Salvia,Christos Dervenis,Peter J. Allen,François Paye,Detlef K. Bartsch,Matthias Löhr,Massimiliano Mutignani,Johanna Laukkarinen,Richard D. Schulick,Roberto Valente,Thomas Seufferlein,Gabriele Capurso,Ajith K. Siriwardena,John P. Neoptolemos,Aldis Pukitis,Ralf Segersvärd,Ali A. Aghdassi,Stefano Andrianello,Peter Bossuyt,Robin Bülow,Karina Cárdenas-Jaén,P. Cortegoso,Martina Fontana,Lena Haeberle,M. Heckler,Andrey Litvin,Kulbir Mann,Christoph W. Michalski,Patrick Michl,Gennaro Nappo,Giampaolo Perri,S. Persson,F. Scheufele,Francesco Sclafani,Manuel Schmidt,L. Venezia,F. Volker,M-P Vullierm,L. Wusten +88 more
TL;DR: A conservative approach is recommended for asymptomatic MCN and IPMN, and Lifelong follow-up of IPMN is recommended in patients who are fit for surgery.
Journal ArticleDOI
Pancreatic adenocarcinoma, Version 2.2021
Margaret A. Tempero,Mokenge P. Malafa,Mahmoud M. Al-Hawary,Stephen W. Behrman,Al B. Benson,Dana Backlund Cardin,E. Gabriela Chiorean,Vincent Chung,Brian G. Czito,Marco Del Chiaro,Mary Dillhoff,Timothy R. Donahue,Efrat Dotan,Cristina R. Ferrone,Christos Fountzilas,Jeffrey M. Hardacre,William G. Hawkins,Kelsey Klute,Andrew H. Ko,John W. Kunstman,Noelle K. LoConte,Andrew M. Lowy,Cassadie Moravek,Eric K. Nakakura,Amol Narang,Jorge Obando,Patricio M. Polanco,Sushanth Reddy,Marsha Reyngold,Courtney L. Scaife,Jeanne Shen,Charles M. Vollmer,Robert A. Wolff,Brian M. Wolpin,Beth Lynn,Giby V. George +35 more
Abstract: Pancreatic cancer is the fourth leading cause of cancer-related death among men and women in the United States. A major challenge in treatment remains patients' advanced disease at diagnosis. The NCCN Guidelines for Pancreatic Adenocarcinoma provides recommendations for the diagnosis, evaluation, treatment, and follow-up for patients with pancreatic cancer. Although survival rates remain relatively unchanged, newer modalities of treatment, including targeted therapies, provide hope for improving patient outcomes. Sections of the manuscript have been updated to be concordant with the most recent update to the guidelines. This manuscript focuses on the available systemic therapy approaches, specifically the treatment options for locally advanced and metastatic disease.
Journal ArticleDOI
ACG Clinical Guideline: Diagnosis and Management of Pancreatic Cysts
TL;DR: This guideline will provide a practical approach to pancreatic cyst management and recommendations for cyst surveillance for the general gastroenterologist.
Journal ArticleDOI
American Gastroenterological Association Technical Review on the Diagnosis and Management of Asymptomatic Neoplastic Pancreatic Cysts
TL;DR: The challenges in evaluating pancreatic cysts are discussed, a rational, evidence-based, cost-effective approach to care of the patient with a pancreas remains poorly defined and the existing data set is critically examined.
References
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Screening behavior of individuals at high risk for colorectal cancer
Eveline M. A. Bleiker,Fred H. Menko,Babs G. Taal,Irma Kluijt,L.D.V. Wever,Miranda A. Gerritsma,Hans F. A. Vasen,Neil K. Aaronson +7 more
TL;DR: Although few high-risk individuals abstain from screening entirely, approximately one in 4 deviates significantly from the recommended frequency of screening.
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Branch-Duct Intraductal Papillary Mucinous Neoplasms: Observations in 145 Patients Who Underwent Resection
Journal ArticleDOI
Frozen sectioning of the pancreatic cut surface during resection of intraductal papillary mucinous neoplasms of the pancreas is useful and reliable: a prospective evaluation.
Anne Couvelard,Alain Sauvanet,Reza Kianmanesh,Pascal Hammel,Nathalie Colnot,Philippe Lévy,Philippe Ruszniewski,Pierre Bedossa,Jacques Belghiti +8 more
TL;DR: Results of FS of the transection margin are confirmed by definitive examination in 94% of cases and allows adequate resection in 97% of patients.
Journal ArticleDOI
Prediction of invasive carcinoma in branch type intraductal papillary mucinous neoplasms of the pancreas
Atsushi Kanno,Kennichi Satoh,Morihisa Hirota,Shin Hamada,Jun Umino,Hiromichi Itoh,Atsushi Masamune,Tohru Asakura,Tooru Shimosegawa +8 more
TL;DR: It is suggested that careful imaging study of the entire pancreas in addition to tumor lesions and measurement of serum CEA and CA19-9 would be required to find out the development of the two types of invasive carcinoma in BD-IPMN.
Journal ArticleDOI
Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms.
TL;DR: Management of pancreatic cysts can be guided using novel Markov-based clinical nomograms, and depends on age, cyst size, comorbidities, and whether patients value overall survival vs quality-adjusted survival.