Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
Van-Mai Cao-Lormeau,Alexandre Blake,Sandrine Mons,Stéphane Lastère,Claudine Roche,Jessica Vanhomwegen,Timothée Dub,Laure Baudouin,Anita Teissier,P. Larre,Anne-Laure Vial,Christophe Decam,Valérie Choumet,Susan K. Halstead,Hugh J. Willison,Lucile Musset,Jean-Claude Manuguerra,Philippe Desprès,Emmanuel Fournier,Henri-Pierre Mallet,Didier Musso,Arnaud Fontanet,Arnaud Fontanet,Jean Neil,Frédéric Ghawché +24 more
TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.About:
This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.read more
Citations
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Nuclear localization of Zika virus NS5 contributes to suppression of type I interferon production and response.
TL;DR: It is suggested that subcellular localization of NS5 is important for its function on innate immune suppression, which provides new insight into ZIKV pathogenesis.
Journal ArticleDOI
Epidemiology of Zika.
TL;DR: It is pivotal to conduct epidemiological laboratory-based surveillance and studies on the virus’ inherent characteristics to understand the pathophysiology of this infection and develop adequate strategies to mitigate this new threat.
Journal ArticleDOI
Zika Virus: Immune Evasion Mechanisms, Currently Available Therapeutic Regimens, and Vaccines
Arun Asif,Sobia Manzoor,Fatima Tuz-Zahra,Muhammad Saalim,Maliha Ashraf,Javeria Ishtiyaq,Madiha Khalid +6 more
TL;DR: This review presents the highlights of recent advances in understanding immune evasion strategies adapted by ZIKV and existing therapies against the virus.
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High specificity and sensitivity of Zika EDIII-based ELISA diagnosis highlighted by a large human reference panel
Jessica Denis,Sarah Attoumani,Patrick Gravier,Bernard Tenebray,Annabelle Garnier,Sébastien Briolant,Franck de Laval,Véronique Chastres,Gilda Grard,Isabelle Leparc-Goffart,Bruno Coutard,Cyril Badaut +11 more
TL;DR: A ZEDIII-based ELISA is developed that can discriminate between past or current DENV and ZIKV infections, allowing the detection of a serological scar from other flaviviruses, used to confirm exposure of pregnant women or to follow the spread of an endemic disease.
Journal ArticleDOI
Advances in management of Guillain-Barré syndrome.
TL;DR: New diagnostic tools may help to have early and accurate diagnosis in difficult GBS cases, and evidence from experimental studies and recent phase 2 clinical trials suggests that complement inhibition combined with IVIg might improve outcome in GBS.
References
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Journal ArticleDOI
Zika virus outbreak on Yap Island, Federated States of Micronesia.
Mark R. Duffy,Tai-Ho Chen,W. Thane Hancock,Ann M. Powers,Jacob L. Kool,Robert S. Lanciotti,Moses Pretrick,Maria Marfel,Stacey Holzbauer,Christine Dubray,Laurent Guillaumot,Anne Griggs,Martin Bel,Amy J. Lambert,Janeen Laven,Olga I. Kosoy,Amanda J. Panella,Brad J. Biggerstaff,Marc Fischer,Edward B. Hayes +19 more
TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
Journal ArticleDOI
Zika Virus (I). Isolations and serological specificity
TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
Journal ArticleDOI
Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007
Robert S. Lanciotti,Olga Kosoy,Janeen Laven,Jason O. Velez,Amy J. Lambert,Alison J. Johnson,Stephanie M. Stanfield,Mark R. Duffy +7 more
TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article
[Guillain-Barré syndrome].
TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
Journal ArticleDOI
First report of autochthonous transmission of Zika virus in Brazil
Camila Zanluca,Vanessa Campos Andrade de Melo,Ana Luiza Pamplona Mosimann,Glauco Igor Viana dos Santos,Claudia Nunes Duarte dos Santos,Kleber Giovanni Luz +5 more
TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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