Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
Van-Mai Cao-Lormeau,Alexandre Blake,Sandrine Mons,Stéphane Lastère,Claudine Roche,Jessica Vanhomwegen,Timothée Dub,Laure Baudouin,Anita Teissier,P. Larre,Anne-Laure Vial,Christophe Decam,Valérie Choumet,Susan K. Halstead,Hugh J. Willison,Lucile Musset,Jean-Claude Manuguerra,Philippe Desprès,Emmanuel Fournier,Henri-Pierre Mallet,Didier Musso,Arnaud Fontanet,Arnaud Fontanet,Jean Neil,Frédéric Ghawché +24 more
TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.About:
This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.read more
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The Envelope Residues E152/156/158 of Zika Virus Influence the Early Stages of Virus Infection in Human Cells.
Sandra Bos,Wildriss Viranaicken,Etienne Frumence,Ge Li,Philippe Desprès,Richard Y. Zhao,Gilles Gadea +6 more
TL;DR: The data highlight an important contribution of E-152/156/158 residues to the early steps of ZIKV infection in human cells, which are associated with an increased efficiency of viral membrane fusion inside infected cells due to conformational changes of E protein that enhance exposure of the fusion loop.
Journal ArticleDOI
Protective Zika vaccines engineered to eliminate enhancement of dengue infection via immunodominance switch.
Lianpan Dai,Lianpan Dai,Kun Xu,Jinhe Li,Qingrui Huang,Jian Song,Yuxuan Han,Tianyi Zheng,Ping Gao,Xuancheng Lu,Huabing Yang,Kefang Liu,Qianfeng Xia,Qihui Wang,Yan Chai,Jianxun Qi,Jinghua Yan,George F. Gao +17 more
TL;DR: In this paper, the authors design ZIKV immunogens engineered to change the FLE conformation but preserve neutralizing epitopes, which is an important safety concern for vaccine development against dengue virus.
Spreading News: The Coverage Of Epidemics By American Newspapers And Its Effects On Audiences - A Crisis Communication Approach
TL;DR: Analysis of coverage of epidemics in leading newspapers demonstrated substantial discrepancies between what CDC aims to communicate during epidemics and what the media actually disseminated to the public, including ways to improve cooperation with journalists and the use of alternative direct-channels for filling gaps in news media coverage.
Journal ArticleDOI
Binding recognition of substrates in NS2B/NS3 serine protease of Zika virus revealed by molecular dynamics simulations.
TL;DR: In this article, classical molecular dynamics simulations were performed on the ZIKV NS2B/NS3 serine protease in complex with four peptide substrates to investigate the binding recognition and protein-substrate interactions.
Journal ArticleDOI
Review: A neglected Flavivirus: an update on Zika virus in 2016 and the future direction of research.
TL;DR: A focussed review of the literature on ZIKV to date is provided, with perspectives on the direction of future research.
References
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Journal ArticleDOI
Zika virus outbreak on Yap Island, Federated States of Micronesia.
Mark R. Duffy,Tai-Ho Chen,W. Thane Hancock,Ann M. Powers,Jacob L. Kool,Robert S. Lanciotti,Moses Pretrick,Maria Marfel,Stacey Holzbauer,Christine Dubray,Laurent Guillaumot,Anne Griggs,Martin Bel,Amy J. Lambert,Janeen Laven,Olga I. Kosoy,Amanda J. Panella,Brad J. Biggerstaff,Marc Fischer,Edward B. Hayes +19 more
TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
Journal ArticleDOI
Zika Virus (I). Isolations and serological specificity
TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
Journal ArticleDOI
Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007
Robert S. Lanciotti,Olga Kosoy,Janeen Laven,Jason O. Velez,Amy J. Lambert,Alison J. Johnson,Stephanie M. Stanfield,Mark R. Duffy +7 more
TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article
[Guillain-Barré syndrome].
TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
Journal ArticleDOI
First report of autochthonous transmission of Zika virus in Brazil
Camila Zanluca,Vanessa Campos Andrade de Melo,Ana Luiza Pamplona Mosimann,Glauco Igor Viana dos Santos,Claudia Nunes Duarte dos Santos,Kleber Giovanni Luz +5 more
TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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