Guillain-Barré Syndrome outbreak associated with Zika virus infection in French Polynesia: a case-control study
Van-Mai Cao-Lormeau,Alexandre Blake,Sandrine Mons,Stéphane Lastère,Claudine Roche,Jessica Vanhomwegen,Timothée Dub,Laure Baudouin,Anita Teissier,P. Larre,Anne-Laure Vial,Christophe Decam,Valérie Choumet,Susan K. Halstead,Hugh J. Willison,Lucile Musset,Jean-Claude Manuguerra,Philippe Desprès,Emmanuel Fournier,Henri-Pierre Mallet,Didier Musso,Arnaud Fontanet,Arnaud Fontanet,Jean Neil,Frédéric Ghawché +24 more
TLDR
This is the first study providing evidence for Zika virus infection causing Guillain-Barré syndrome, and because Zika virus is spreading rapidly across the Americas, at risk countries need to prepare for adequate intensive care beds capacity to manage patients with Guillay-B Barré syndrome.About:
This article is published in The Lancet.The article was published on 2016-04-09 and is currently open access. It has received 1925 citations till now. The article focuses on the topics: Zika virus & Zika virus disease.read more
Citations
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Zika virus infection: epidemiology, clinical manifestations and diagnosis.
TL;DR: The findings illustrate the emergence of a viral disease with the identification of new associated disorders, new modes of transmission, including maternal–foetal and sexual transmission.
Epidemiology of Zika Virus Infection
TL;DR: Increased surveillance in several Southeast Asian counties has led to increased case recognition, including an outbreak in Singapore, and the first reports of birth defects linked to ZIKAV in the region.
Journal ArticleDOI
Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome.
Zachary Klase,Svetlana Khakhina,Adriano de Bernardi Schneider,Michael V. Callahan,Jill Glasspool-Malone,Robert W. Malone +5 more
TL;DR: This review analyzes Zika fetal neuropathogenesis from a comparative pathology perspective, using the historic metaphor of “TORCH” viral pathogenesis to provide context and identifies common themes and mechanisms that may illuminate the observed pathology.
Journal ArticleDOI
Maternal immunity and antibodies to dengue virus promote infection and Zika virus-induced microcephaly in fetuses.
Abhay P. S. Rathore,Abhay P. S. Rathore,Wilfried A. A. Saron,Ting Lim,Nusrat Jahan,Ashley L. St. John,Ashley L. St. John +6 more
TL;DR: It is shown that DENV-specific antibodies in ZikV-infected pregnant mice enhance vertical ZIKV transmission and result in a severe microcephaly-like syndrome, which was dependent on the neonatal Fc receptor, FcRN.
Journal ArticleDOI
Epigallocatechin gallate, an active green tea compound inhibits the Zika virus entry into host cells via binding the envelope protein.
TL;DR: The binding site (Site1) of EGCG on envelope protein is investigated and the insights into various interactions of molecule with the binding site using molecular docking studies are provided and the possible associated mechanism of inhibition of ZIKV entry by E GCG molecule is proposed.
References
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Zika virus outbreak on Yap Island, Federated States of Micronesia.
Mark R. Duffy,Tai-Ho Chen,W. Thane Hancock,Ann M. Powers,Jacob L. Kool,Robert S. Lanciotti,Moses Pretrick,Maria Marfel,Stacey Holzbauer,Christine Dubray,Laurent Guillaumot,Anne Griggs,Martin Bel,Amy J. Lambert,Janeen Laven,Olga I. Kosoy,Amanda J. Panella,Brad J. Biggerstaff,Marc Fischer,Edward B. Hayes +19 more
TL;DR: This outbreak of Zika virus illness in Micronesia represents transmission of Zikairus outside Africa and Asia and clinicians and public health officials should be aware of the risk of further expansion of Zika viruses transmission.
Journal ArticleDOI
Zika Virus (I). Isolations and serological specificity
TL;DR: Cross neutralization tests indicate that Zika virus is not related to yellow fever, Hawaii dengue nor to the FA and GD VII strains of Theiler's mouse encephalomyelitis virus.
Journal ArticleDOI
Genetic and Serologic Properties of Zika Virus Associated with an Epidemic, Yap State, Micronesia, 2007
Robert S. Lanciotti,Olga Kosoy,Janeen Laven,Jason O. Velez,Amy J. Lambert,Alison J. Johnson,Stephanie M. Stanfield,Mark R. Duffy +7 more
TL;DR: The full coding region nucleic acid sequence and serologic properties of the virus were identified and the virus was identified as Crimean-Congo-Wales coronavirus.
Journal Article
[Guillain-Barré syndrome].
TL;DR: High-dose of intravenous immunoglobulin (0.4 g/kg daily for 5 days) and PE are equally effective in intermediate and severe forms and the choice between the two treatments depends on their respective contra-indications and local availability.
Journal ArticleDOI
First report of autochthonous transmission of Zika virus in Brazil
Camila Zanluca,Vanessa Campos Andrade de Melo,Ana Luiza Pamplona Mosimann,Glauco Igor Viana dos Santos,Claudia Nunes Duarte dos Santos,Kleber Giovanni Luz +5 more
TL;DR: Phylogenetic analysis suggests that the ZikV identified belongs to the Asian clade, the first report of ZIKV infection in Brazil, and the result was confirmed by DNA sequencing.
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